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H21.261 ICD-10-CM Code: Iris atrophy (essential) (progressive), right eye

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FY 2026 Apr update / Diseases of the eye and adnexa (H00-H59) / Disorders of sclera, cornea, iris and ciliary body (H15-H22)

H21.261

Billable / SpecificICD-10-CMOfficial ICD-10-CMCodebook guidance

Iris atrophy (essential) (progressive), right eye

Progressive thinning and wasting of the iris tissue in the right eye, occurring without an identifiable underlying cause.

CMS-HCC V28

0

0

RAF 0

CMS-HCC V24

0

0

RAF 0

ACA/HHS

0

0

RAF 0

ESRD/PACE

0

0

RAF 0

RXHCC

0

0

RAF 0

Code Trumping

Basket needed

Code Book Path

Official
H21.2Degeneration of iris and ciliary body
H21.26Iris atrophy (essential) (progressive)
H21.261Iris atrophy (essential) (progressive), right eye

Inclusion Terms

Official

ICD-10-CM does not list inclusion terms for H21.261 in this effective period.

Excludes 2

Official

ICD-10-CM does not list Excludes 2 notes for H21.261 in this effective period.

Related Child Codes

Official
H21.262Iris atrophy (essential) (progressive), left eye
H21.263Iris atrophy (essential) (progressive), bilateral
H21.269Iris atrophy (essential) (progressive), unspecified eye

Includes

Official

ICD-10-CM does not list Includes notes for H21.261 in this effective period.

Excludes 1

Official

ICD-10-CM does not list Excludes 1 notes for H21.261 in this effective period.

Code First

Official

ICD-10-CM does not list Code First sequencing instructions for H21.261 in this effective period.

Use Additional

Official

ICD-10-CM does not list Use Additional Code instructions for H21.261 in this effective period.

Code Also

Official

ICD-10-CM does not list Code Also instructions for H21.261 in this effective period.

Buddy Documentation Tip

HCC Buddy guidance
Verify laterality is documented as right eye to ensure accurate code selection
Distinguish from secondary iris atrophy caused by other conditions like glaucoma or inflammation

Last updated: FY2026 ICD-10-CM Apr update, Apr 1, 2026 through Sep 30, 2026. CMS-HCC V28 is 100% phased in for payment year 2026.

Is H21.261 an HCC code?

No. H21.261 is a billable ICD-10-CM code but does not map to any HCC category in V28, V24, ESRD, or RxHCC.

This code does not map to an HCC category in any model (V28, V24, ESRD, RxHCC).

What This Code Means

H21.261 is the ICD-10-CM diagnosis code for iris atrophy (essential) (progressive), right eye. Progressive thinning and wasting of the iris tissue in the right eye, occurring without an identifiable underlying cause. H21.261 sits in the ICD-10-CM chapter for diseases of the eye and adnexa (h00-h59), within the section covering disorders of sclera, cornea, iris and ciliary body (h15-h22).

H21.261 is a billable ICD-10-CM code but does not map to a payment HCC under the CMS-HCC V28, V24, ESRD, or RxHCC risk adjustment models. It can be reported on Medicare Advantage encounter data submissions but it does not contribute to a beneficiary's RAF score and therefore does not affect risk-adjusted payments to the plan.

Verify laterality is documented as right eye to ensure accurate code selection.

HCC Buddy maintains structured V28 and V24 mapping, RAF weights, and MEAT documentation criteria for H21.261 sourced directly from the CMS-HCC risk adjustment model files and the CMS ICD-10-CM code set.

Coding Tips

  • Verify laterality is documented as right eye to ensure accurate code selection
  • Distinguish from secondary iris atrophy caused by other conditions like glaucoma or inflammation

Child Codes

Code Hierarchy

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