G73.1
BillableLambert-Eaton syndrome in neoplastic disease
HCC Category Mapping
V28HCC 196 — Myasthenia Gravis/Myoneural Conditions and Guillain-Barre
0.402V24HCC 75 — Myasthenia Gravis/Myoneural Conditions and Guillain-Barre Syndrome
0.425ESRDHCC 75 — Myasthenia Gravis/Myoneural Conditions and Guillain-Barre Syndrome
0.000RxHCCHCC 153 — Myasthenia Gravis/Myoneural Conditions
0.000What This Code Means
Lambert-Eaton syndrome occurring as a complication of cancer. This is an autoimmune disorder affecting the connection between nerves and muscles, triggered by malignancy.
Coding Tips
- •Always code the underlying neoplasm first, followed by this code to show the relationship between cancer and the syndrome
- •Document the type of cancer and whether it is small cell lung cancer, which is the most common association
Clinical Significance
Lambert-Eaton syndrome in neoplastic disease is a paraneoplastic condition most commonly associated with small cell lung cancer, where cancer triggers an autoimmune attack on presynaptic calcium channels. This diagnosis indicates both malignancy and a significant neurological complication, reflecting extremely complex patient care. Capturing this code alongside the underlying malignancy is critical for accurate risk adjustment.
Documentation Requirements
- ✓Documentation of the underlying neoplasm (most commonly small cell lung cancer)
- ✓Clinical features of Lambert-Eaton syndrome: proximal weakness, autonomic dysfunction, hyporeflexia
- ✓Electrodiagnostic confirmation: incremental response on repetitive nerve stimulation
- ✓Voltage-gated calcium channel antibody testing results
- ✓The underlying neoplasm code must be sequenced first
- ✓Provider's explicit documentation linking the Lambert-Eaton syndrome to the malignancy
Excludes 1 — Do NOT code together
Commonly Confused Codes
G70.80 — Lambert-Eaton syndrome, unspecified is for cases without an identified underlying diseaseG70.81 — Lambert-Eaton syndrome in disease classified elsewhere is for non-neoplastic underlying diseasesG70.00 — Myasthenia gravis without exacerbation is a different autoimmune neuromuscular disorderG73.3 — Myasthenic syndromes in other diseases is for secondary myasthenic symptoms, not Lambert-Eaton syndrome
Code Hierarchy
└G73Disorders of myoneural junction and muscle in diseases classified elsewhere└G73.1Lambert-Eaton syndrome in neoplastic disease
└G73.1Lambert-Eaton syndrome in neoplastic disease