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G31.82

Billable

Leigh's disease

Last updated: FY2026 ICD-10-CM (Oct 1, 2025 – Sep 30, 2026) | CMS-HCC V28 (100% phase-in, PY2026)

Is G31.82 an HCC code?

Yes. G31.82 maps to Dementia, Mild or Unspecified under the CMS-HCC V28 risk adjustment model.

HCC Category Mapping

V28HCC 127Dementia, Mild or Unspecified
0.464
RxHCCHCC 112Dementia and Other Specified Brain Disorders
0.000

RAF weights shown are the community, non-dual, aged base weights from the CMS risk adjustment model file. Actual per-patient RAF contribution depends on member segment, interactions, and the model year used by the payer. V28 is the CMS-HCC model phased in over payment years 2024–2026; V24 remains in use during the transition and for historical data.

MEAT Criteria for G31.82

For G31.82 to count as a valid HCC diagnosis in a given encounter, the provider's documentation must show MEAT: Monitor, Evaluate, Assess, or Treat. A diagnosis from a prior year does not carry forward automatically — it has to be re-documented and supported each calendar year.

  • MMonitor: signs, symptoms, disease progression, or lab trending documented in the note
  • EEvaluate: test results, medication response, or physical findings reviewed by the provider
  • AAssess: explicit mention in the assessment or plan with acknowledgment of status
  • TTreat: medication, referral, procedure, therapy, or counseling tied to the diagnosis

Only one of M/E/A/T is required to support the code, but the documentation must be specific enough to show that the provider actually addressed G31.82 during that encounter — not just copy-forwarded from a problem list.

What This Code Means

G31.82 is the ICD-10-CM diagnosis code for leigh's disease. Leigh's disease is a rare inherited neurological disorder affecting energy production in cells, causing progressive brain and muscle deterioration, typically starting in infancy. G31.82 sits in the ICD-10-CM chapter for diseases of the nervous system (g00-g99), within the section covering other degenerative diseases of the nervous system (g30-g32).

Under the CMS-HCC V28 risk adjustment model, G31.82 maps to Dementia, Mild or Unspecified (HCC 127) with a community, non-dual, aged base RAF weight of 0.464. G31.82 was not retained as a payment HCC under the older V24 model, so V28 introduced or recategorized it during the 2024–2026 phase-in. V28 is the CMS-HCC risk adjustment model that reached 100% phase-in for payment year 2026, replacing V24 which was used during the PY2024–PY2025 transition.

This is a mitochondrial disorder; document genetic confirmation when available. Because G31.82 maps to a payment HCC, the provider's documentation must satisfy MEAT criteria (Monitor, Evaluate, Assess, or Treat) for the encounter to count toward the patient's Medicare Advantage risk adjustment score. When documentation is ambiguous, coders should issue a provider query rather than assume the highest-specificity variant.

HCC Buddy maintains structured V28 and V24 mapping, RAF weights, and MEAT documentation criteria for G31.82 sourced directly from the CMS-HCC risk adjustment model files and the CMS ICD-10-CM code set.

Coding Tips

  • This is a mitochondrial disorder; document genetic confirmation when available
  • Code associated symptoms such as seizures, respiratory issues, and cardiac involvement separately

Clinical Significance

Leigh's disease (subacute necrotizing encephalomyelopathy) is a severe inherited mitochondrial disorder affecting cellular energy production. It causes progressive neurological deterioration including loss of motor skills, breathing difficulties, and organ dysfunction. The diagnosis reflects one of the most serious pediatric neurological conditions, requiring intensive multidisciplinary management.

Documentation Requirements

  • Documentation specifically identifying Leigh's disease or subacute necrotizing encephalomyelopathy
  • Neuroimaging (MRI) showing characteristic bilateral symmetric lesions in basal ganglia and brainstem
  • Genetic or metabolic testing confirming mitochondrial dysfunction
  • Documentation of progressive neurological symptoms (developmental regression, hypotonia, respiratory compromise)
  • Metabolic workup results including lactate levels
  • Current treatment plan addressing nutritional, respiratory, and neurological management

Commonly Confused Codes

Code Hierarchy

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