F13.221
BillableSedative, hypnotic or anxiolytic dependence with intoxication delirium
HCC Category Mapping
V28HCC 137 — Drug Use Disorder/Substance Use Disorder, Moderate/Severe
0.358V24HCC 55 — Drug/Alcohol Dependence
0.334ESRDHCC 55 — Drug/Alcohol Dependence
0.000What This Code Means
A person dependent on sedative, hypnotic, or anti-anxiety medications is experiencing intoxication with delirium, a serious condition involving confusion, disorientation, and altered mental status.
Coding Tips
- •Document specific delirious symptoms such as hallucinations, agitation, or disorientation
- •This is a more severe presentation than uncomplicated intoxication and may require emergency intervention
Clinical Significance
Sedative dependence with intoxication delirium is a medical emergency characterized by acute confusion, disorientation, and potential agitation in a dependent patient who is intoxicated. This condition can be life-threatening and often requires hospitalization. The delirium component significantly increases clinical severity and resource utilization compared to uncomplicated intoxication.
Documentation Requirements
- ✓Documentation of sedative, hypnotic, or anxiolytic dependence
- ✓Clinical findings consistent with delirium: acute onset confusion, fluctuating consciousness, disorientation
- ✓Temporal relationship between substance intoxication and delirium onset
- ✓Glasgow Coma Scale or other mental status assessment documenting delirium severity
- ✓Vital signs and monitoring parameters
- ✓Emergency interventions and treatment provided
Commonly Confused Codes
F13.220 — Dependence with intoxication uncomplicated; no delirium presentF13.231 — Dependence with WITHDRAWAL delirium; delirium occurs during withdrawal, not intoxicationF13.229 — Dependence with intoxication unspecified; use when delirium status is unclearF05 — Delirium due to known physiological condition; not substance-inducedF13.121 — Sedative ABUSE with intoxication delirium; less severe use pattern
Code Hierarchy
└F13Sedative, hypnotic, or anxiolytic related disorders└F13.2Sedative, hypnotic or anxiolytic-related dependence└F13.22Sedative, hypnotic or anxiolytic dependence with intoxication└F13.221Sedative, hypnotic or anxiolytic dependence with intoxication delirium
└F13.221Sedative, hypnotic or anxiolytic dependence with intoxication delirium