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E88.A

Billable

Wasting disease (syndrome) due to underlying condition

HCC Category Mapping

V24HCC 21Protein-Calorie Malnutrition
0.545
ESRDHCC 21Protein-Calorie Malnutrition
0.000

What This Code Means

Severe weight loss and muscle wasting caused by an underlying medical condition, often seen in chronic illnesses or malignancy.

Coding Tips

  • This code requires documentation of an underlying condition causing the wasting; code the primary condition as well
  • Do not use this code for simple malnutrition or cachexia without an identified underlying cause

Clinical Significance

Wasting disease (cachexia) due to an underlying condition represents severe, progressive loss of muscle mass and weight that cannot be fully reversed by nutritional supplementation. It is commonly seen in advanced cancer, heart failure, COPD, HIV, and chronic kidney disease. This code carries a high RAF weight reflecting the severity and poor prognosis associated with cachexia.

Documentation Requirements

  • Diagnosis of wasting disease, wasting syndrome, or cachexia by the provider
  • Identification of the underlying condition causing the wasting
  • Objective evidence: significant weight loss (typically >5% in 6 months), BMI, muscle mass assessment
  • Distinction from simple malnutrition or voluntary weight loss
  • Nutritional assessment and support plan
  • Documentation that wasting is NOT adequately explained by decreased caloric intake alone

Excludes 1 — Do NOT code together

  • cachexia NOS (R64)
  • nutritional marasmus (E41)

Excludes 2 — Not included here, may code separately

Code First

  • underlying condition

Commonly Confused Codes

Code Hierarchy

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