E84.8
BillableCystic fibrosis with other manifestations
Last updated: FY2026 ICD-10-CM (Oct 1, 2025 – Sep 30, 2026) | CMS-HCC V28 (100% phase-in, PY2026)
Is E84.8 an HCC code?
Yes. E84.8 maps to Cystic Fibrosis under the CMS-HCC V28 risk adjustment model (and Cystic Fibrosis under V24).
HCC Category Mapping
RAF weights shown are the community, non-dual, aged base weights from the CMS risk adjustment model file. Actual per-patient RAF contribution depends on member segment, interactions, and the model year used by the payer. V28 is the CMS-HCC model phased in over payment years 2024–2026; V24 remains in use during the transition and for historical data.
MEAT Criteria for E84.8
For E84.8 to count as a valid HCC diagnosis in a given encounter, the provider's documentation must show MEAT: Monitor, Evaluate, Assess, or Treat. A diagnosis from a prior year does not carry forward automatically — it has to be re-documented and supported each calendar year.
- MMonitor: signs, symptoms, disease progression, or lab trending documented in the note
- EEvaluate: test results, medication response, or physical findings reviewed by the provider
- AAssess: explicit mention in the assessment or plan with acknowledgment of status
- TTreat: medication, referral, procedure, therapy, or counseling tied to the diagnosis
Only one of M/E/A/T is required to support the code, but the documentation must be specific enough to show that the provider actually addressed E84.8 during that encounter — not just copy-forwarded from a problem list.
What This Code Means
E84.8 is the ICD-10-CM diagnosis code for cystic fibrosis with other manifestations. This code is used for cystic fibrosis when it affects other body systems beyond the lungs and intestines, such as the liver, sweat glands, or reproductive system. E84.8 sits in the ICD-10-CM chapter for endocrine, nutritional and metabolic diseases (e00-e89), within the section covering metabolic disorders (e70-e88).
Under the CMS-HCC V28 risk adjustment model, E84.8 maps to Cystic Fibrosis (HCC 277) with a community, non-dual, aged base RAF weight of 0.405. Under the older V24 model, E84.8 mapped to the same category but with a base RAF weight of 0.473 — V28 recalibrated weights across the entire model. V28 is the CMS-HCC risk adjustment model that reached 100% phase-in for payment year 2026, replacing V24 which was used during the PY2024–PY2025 transition.
Specify which organ system is affected in documentation to support medical necessity and justify treatment decisions. Because E84.8 maps to a payment HCC, the provider's documentation must satisfy MEAT criteria (Monitor, Evaluate, Assess, or Treat) for the encounter to count toward the patient's Medicare Advantage risk adjustment score. When documentation is ambiguous, coders should issue a provider query rather than assume the highest-specificity variant.
HCC Buddy maintains structured V28 and V24 mapping, RAF weights, and MEAT documentation criteria for E84.8 sourced directly from the CMS-HCC risk adjustment model files and the CMS ICD-10-CM code set.
Coding Tips
- •Specify which organ system is affected in documentation to support medical necessity and justify treatment decisions
- •Do not use this code if pulmonary or intestinal manifestations are the primary focus; use more specific codes instead
Clinical Significance
Cystic fibrosis with other manifestations captures CF involvement beyond the pulmonary and intestinal systems, including CF-related diabetes, hepatobiliary disease, male infertility, nasal polyps, and musculoskeletal complications. These multi-system effects reflect the complex nature of CF management.
Documentation Requirements
- ✓Confirmed cystic fibrosis diagnosis
- ✓Specific non-pulmonary, non-intestinal manifestation documented (CF-related diabetes, liver disease, infertility, sinusitis, arthropathy)
- ✓Current management of the specific manifestation
- ✓Explanation of why the manifestation is attributed to CF rather than a separate condition
- ✓Overall CF disease status and complexity documentation
Commonly Confused Codes
- •E84.0 — Cystic fibrosis with pulmonary manifestations: for lung involvement specifically
- •E84.19 — Cystic fibrosis with other intestinal manifestations: for GI involvement specifically
- •E84.9 — Cystic fibrosis, unspecified: less specific; use E84.8 when a specific non-pulmonary/non-GI manifestation is documented
- •E13.9 — Other specified diabetes mellitus: CF-related diabetes may use both E84.8 and an E13 code