E83.110

Billable

Hereditary hemochromatosis

HCC Category Mapping

V24HCC 23 — Other Significant Endocrine and Metabolic Disorders

0.230

ESRDHCC 23 — Other Significant Endocrine and Metabolic Disorders

0.000

RxHCCHCC 43 — Other Significant Endocrine and Metabolic Disorders

0.000

What This Code Means

A genetic condition where the body absorbs and stores too much iron from food, leading to organ damage over time.

Coding Tips

•This is the most specific code for hereditary hemochromatosis; use this when the hereditary form is confirmed
•Verify documentation specifies 'hereditary' or 'genetic' hemochromatosis before assigning this code

Clinical Significance

Hereditary hemochromatosis is a genetic iron overload disorder that, left untreated, leads to progressive organ damage including cirrhosis, cardiomyopathy, diabetes, and arthropathy. It is a risk-adjustment-relevant condition under CMS-HCC V24 because it reflects ongoing metabolic burden requiring lifelong monitoring and therapeutic phlebotomy.

Documentation Requirements

✓Confirmed hereditary/genetic etiology (e.g., HFE gene mutation C282Y or H63D documented)
✓Serum ferritin and transferrin saturation levels
✓Current treatment plan (therapeutic phlebotomy schedule or iron chelation)
✓Documentation of end-organ assessment (liver, heart, pancreas, joints)
✓Family history supporting hereditary nature

Commonly Confused Codes

E83.118 — Other hemochromatosis: use when the hemochromatosis is NOT hereditary (e.g., transfusional iron overload)E83.119 — Hemochromatosis, unspecified: use only when type cannot be determined; less specific and does NOT map to HCC E83.10 — Disorder of iron metabolism, unspecified: non-specific code that should be avoided when hemochromatosis is documented E61.1 — Iron deficiency: opposite condition (iron deficiency rather than overload)

Code Hierarchy

└E83Disorders of mineral metabolism └E83.1Disorders of iron metabolism └E83.11Hemochromatosis └E83.110Hereditary hemochromatosis

└E83.110Hereditary hemochromatosis