What is ICD-10 code E83.110?

E83.110 is the ICD-10-CM diagnosis code for Hereditary hemochromatosis. A genetic condition where the body absorbs and stores too much iron from food, leading to organ damage over time. It belongs to the ICD-10-CM chapter for endocrine, nutritional and metabolic diseases (e00-e89). E83.110 is a billable code, meaning it can be reported on a claim as a primary or secondary diagnosis when supported by documentation. E83.110 is part of the FY2026 ICD-10-CM code set published by the CMS National Center for Health Statistics and used on Medicare, Medicaid, and commercial claims in the United States.

Yes. E83.110 is a billable ICD-10-CM code that can be reported on professional and institutional claims as a primary or secondary diagnosis when the provider documentation supports the specific condition described. Billable codes in ICD-10-CM are coded to the highest level of specificity available for the documented diagnosis. E83.110 is current for fiscal year 2026 and remains in the active CMS ICD-10-CM code set published by the National Center for Health Statistics.

Which HCC does E83.110 map to under V28?

E83.110 has no payable CMS-HCC V28 mapping in the final FY2026 CMS file.

What RAF reference is published for E83.110?

E83.110 has no V28 reference coefficient because the final FY2026 source verifies no payable V28 mapping.

What is the V28 vs V24 difference for E83.110?

E83.110 has verified no payable V28 mapping in the final FY2026 source. Select a historical effective period before making any V24 comparison.

What documentation supports E83.110?

This is the most specific code for hereditary hemochromatosis; use this when the hereditary form is confirmed Verify documentation specifies 'hereditary' or 'genetic' hemochromatosis before assigning this code E83.110 is not a CMS-HCC V28 payment code in the verified current source, so MEAT is not the payment hook. Documentation still has to support the diagnosis if you report it.

2026 ICD-10-CM E83.110: Hereditary hemochromatosis

E83.110 is not a CMS-HCC payment code. MEAT criteria · RAF Calculator · free HCC coding tools

ICD-10-CM Code View

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Code lookupE83.110Effective periodFY2026 Apr Update (Apr 1-Sep 30)

FY 2026 Apr update / Endocrine, nutritional and metabolic diseases (E00-E89) / Metabolic disorders (E70-E88)

E83.110

Billable / SpecificICD-10-CMOfficial ICD-10-CMCodebook guidance

Hereditary hemochromatosis

A genetic condition where the body absorbs and stores too much iron from food, leading to organ damage over time.

Buddy Insight

Hereditary hemochromatosis is a genetic iron overload disorder that, left untreated, leads to progressive organ damage including cirrhosis, cardiomyopathy, diabetes, and arthropathy.

CMS-HCC V28

N/A

—

Not risk-adjusted for this model/period.

Not mapped

CMS-HCC V24

Historical

Not used for standard CY2026 Medicare Advantage payment. Select a historical period to review V24.

Not used for CY2026 payment

ACA/HHS

N/A

—

Not risk-adjusted for this model/period.

Not mapped

ESRD/PACE

Mapped

HCC 23

Other Significant Endocrine a...

Code-level coefficient reference

RXHCC

Mapped

HCC 43

Pituitary, Adrenal Gland, and...

Code-level coefficient reference

Code Book Path

Official

E83.1Disorders of iron metabolism

E83.11Hemochromatosis

E83.110Hereditary hemochromatosis

Inclusion Terms

Official

Bronzed diabetes
Pigmentary cirrhosis (of liver)
Primary (hereditary) hemochromatosis

Excludes 2

Official

ICD-10-CM does not list Excludes 2 notes for E83.110 in this effective period.

Related Child Codes

Official

E83.111Hemochromatosis due to repeated red blood cell transfusions

E83.118Other hemochromatosis

E83.119Hemochromatosis, unspecified

Includes

Official

ICD-10-CM does not list Includes notes for E83.110 in this effective period.

Excludes 1

Official

GALD (P78.84)
Gestational alloimmune liver disease (P78.84)
Neonatal hemochromatosis (P78.84)

Code First

Official

ICD-10-CM does not list Code First sequencing instructions for E83.110 in this effective period.

Use Additional

Official

ICD-10-CM does not list Use Additional Code instructions for E83.110 in this effective period.

Code Also

Official

ICD-10-CM does not list Code Also instructions for E83.110 in this effective period.

Buddy Documentation Tip

HCC Buddy guidance

Confirmed hereditary/genetic etiology (e.g., HFE gene mutation C282Y or H63D documented)

Serum ferritin and transferrin saturation levels

Current treatment plan (therapeutic phlebotomy schedule or iron chelation)

Documentation of end-organ assessment (liver, heart, pancreas, joints)

MEAT Support

HCC Buddy guidance

Confirmed hereditary/genetic etiology (e.g., HFE gene mutation C282Y or H63D documented)

Serum ferritin and transferrin saturation levels

Current treatment plan (therapeutic phlebotomy schedule or iron chelation)

Documentation of end-organ assessment (liver, heart, pancreas, joints)

Audit Caution

HCC Buddy guidance

Assigning the hereditary code when documentation only states 'hemochromatosis' without specifying hereditary etiology — query the provider

Missing the HCC capture by defaulting to unspecified E83.119 when hereditary type is documented

Failing to link secondary conditions (diabetes, cirrhosis, cardiomyopathy) caused by iron overload as separate reportable diagnoses

Not differentiating between hereditary hemochromatosis and secondary/acquired iron overload from chronic transfusions

Common Mistakes

HCC Buddy guidance

E83.118 — Other hemochromatosis: use when the hemochromatosis is NOT hereditary (e.g., transfusional iron overload)

E83.119 — Hemochromatosis, unspecified: use only when type cannot be determined; less specific and does NOT map to HCC

E83.10 — Disorder of iron metabolism, unspecified: non-specific code that should be avoided when hemochromatosis is documented

E61.1 — Iron deficiency: opposite condition (iron deficiency rather than overload)

Current with CMS: FY2026 ICD-10-CM Apr 1 update (effective Apr 1 – Sep 30, 2026) · CMS-HCC V28, 100% phased in for payment year 2026. FY2027 code set already staged for October 1, 2026. How HCC Buddy stays current →

Is E83.110 an HCC code?

E83.110 is not in the CMS-HCC V28 or V24 community payment model. E83.110 has a separate mapping under the CMS-HCC ESRD model (HCC 23 (Other Significant Endocrine and Metabolic Disorders)) and the Part D RxHCC model (HCC 43 (Pituitary, Adrenal Gland, and Other Endocrine and Metabolic Disorders)); the applicable result needs member context.

Code: E83.110
Description: Hereditary hemochromatosis
HCC (V28): No CMS-HCC V28 mapping
RAF reference coefficient: —
Billable: Yes
Payment year: 2026

HCC Category Mapping

ESRDHCC 23, Other Significant Endocrine and Metabolic Disorders

Not separately weighted

RxHCCHCC 43, Pituitary, Adrenal Gland, and Other Endocrine and Metabolic Disorders

Not separately weighted

These are source-labeled model coefficients, not member totals. A category may still be removed by hierarchy or model cleanup rules. Weights are not directly comparable across models: CMS-HCC V28 and V24 use Community, Non-Dual, Aged; ESRD uses the dialysis continuing-enrollee model; RxHCC is the Part D continuing-enrollee, non-low-income, aged weight (a larger scale than CMS-HCC). ACA/HHS has no single weight — it varies by metal level. Actual per-patient RAF contribution depends on member context, hierarchy and cleanup rules, interactions, and the model year used by the payer. V28 is the CMS-HCC model phased in over payment years 2024–2026; V24 remains available for historical review.

Work E83.110 in the Code Book — tabular path, V28 RAF reference, and MEAT checklist →

MEAT Criteria for E83.110

For E83.110 to count as a valid HCC diagnosis in a given encounter, the provider's documentation must show MEAT: Monitor, Evaluate, Assess, or Treat. A diagnosis from a prior year does not carry forward automatically, it has to be re-documented and supported each calendar year.

MMonitor: signs, symptoms, disease progression, or lab trending documented in the note
EEvaluate: test results, medication response, or physical findings reviewed by the provider
AAssess: explicit mention in the assessment or plan with acknowledgment of status
TTreat: medication, referral, procedure, therapy, or counseling tied to the diagnosis

Only one of M/E/A/T is required to support the code, but the documentation must be specific enough to show that the provider actually addressed E83.110 during that encounter, not just copy-forwarded from a problem list.

Coder workflow notes

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What This Code Means

E83.110 is the ICD-10-CM diagnosis code for hereditary hemochromatosis. A genetic condition where the body absorbs and stores too much iron from food, leading to organ damage over time. E83.110 sits in the ICD-10-CM chapter for endocrine, nutritional and metabolic diseases (e00-e89), within the section covering metabolic disorders (e70-e88).

E83.110 has no mapping under the CMS-HCC V28 or V24 community payment models. E83.110 has a separate mapping under the CMS-HCC ESRD model (HCC 23 (Other Significant Endocrine and Metabolic Disorders)) and the Part D RxHCC model (HCC 43 (Pituitary, Adrenal Gland, and Other Endocrine and Metabolic Disorders)); the applicable result needs member context. Do not assign V28 risk adjustment value from this page; verify the applicable model and payment year before using this code for risk adjustment.

This is the most specific code for hereditary hemochromatosis; use this when the hereditary form is confirmed.

HCC Buddy maintains structured V28 and V24 mapping, source-labeled coefficient references, and MEAT documentation criteria for E83.110 sourced directly from the CMS-HCC risk adjustment model files and the CMS ICD-10-CM code set.

Coding Tips

•This is the most specific code for hereditary hemochromatosis; use this when the hereditary form is confirmed
•Verify documentation specifies 'hereditary' or 'genetic' hemochromatosis before assigning this code

Clinical Significance

Hereditary hemochromatosis is a genetic iron overload disorder that, left untreated, leads to progressive organ damage including cirrhosis, cardiomyopathy, diabetes, and arthropathy. It is a risk-adjustment-relevant condition under CMS-HCC V24 because it reflects ongoing metabolic burden requiring lifelong monitoring and therapeutic phlebotomy.

Documentation Requirements

✓Confirmed hereditary/genetic etiology (e.g., HFE gene mutation C282Y or H63D documented)
✓Serum ferritin and transferrin saturation levels
✓Current treatment plan (therapeutic phlebotomy schedule or iron chelation)
✓Documentation of end-organ assessment (liver, heart, pancreas, joints)
✓Family history supporting hereditary nature

Commonly Confused Codes

•E83.118: Other hemochromatosis: use when the hemochromatosis is NOT hereditary (e.g., transfusional iron overload)
•E83.119: Hemochromatosis, unspecified: use only when type cannot be determined; less specific and does NOT map to HCC
•E83.10: Disorder of iron metabolism, unspecified: non-specific code that should be avoided when hemochromatosis is documented
•E61.1: Iron deficiency: opposite condition (iron deficiency rather than overload)