What is ICD-10 code E83.10?

E83.10 is the ICD-10-CM diagnosis code for Disorder of iron metabolism, unspecified. A metabolic disorder affecting iron levels in the body where the specific type or cause has not been identified. It belongs to the ICD-10-CM chapter for endocrine, nutritional and metabolic diseases (e00-e89). E83.10 is a billable code, meaning it can be reported on a claim as a primary or secondary diagnosis when supported by documentation. E83.10 is part of the FY2026 ICD-10-CM code set published by the CMS National Center for Health Statistics and used on Medicare, Medicaid, and commercial claims in the United States.

Yes. E83.10 is a billable ICD-10-CM code that can be reported on professional and institutional claims as a primary or secondary diagnosis when the provider documentation supports the specific condition described. Billable codes in ICD-10-CM are coded to the highest level of specificity available for the documented diagnosis. E83.10 is current for fiscal year 2026 and remains in the active CMS ICD-10-CM code set published by the National Center for Health Statistics.

What is the V28 vs V24 difference for E83.10?

E83.10 does not map to a payment HCC under either the CMS-HCC V28 risk adjustment model or the older V24 model. V28 reached 100% phase-in for payment year 2026, replacing V24 which was used during the PY2024–PY2025 transition. Because neither model rewards E83.10 with a risk adjustment factor, it contributes zero to a Medicare Advantage beneficiary's RAF score in either version. Coders should check whether provider documentation supports a more specific child code that does map to a payment HCC.

What should coders know when reporting E83.10?

This is a non-specific code; attempt to identify whether the disorder is hemochromatosis, iron deficiency, or another specific iron metabolism condition Review for more specific iron metabolism codes (E83.11 for hemochromatosis) before using this unspecified code

E83.10: Disorder of iron metabolism, unspecified — ICD-10

ICD-10-CM Code View

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Code lookupE83.10Effective periodFY2026 Apr Update (Apr 1-Sep 30)

FY 2026 Apr update / Endocrine, nutritional and metabolic diseases (E00-E89) / Metabolic disorders (E70-E88)

E83.10

Billable / SpecificICD-10-CMOfficial ICD-10-CMCodebook guidance

Disorder of iron metabolism, unspecified

A metabolic disorder affecting iron levels in the body where the specific type or cause has not been identified.

Buddy Insight

Disorder of iron metabolism, unspecified covers confirmed iron metabolism disorders without specification of the type.

CMS-HCC V28

Not risk-adjusted for this model/period.

RAF 0

CMS-HCC V24

Not risk-adjusted for this model/period.

RAF 0

ACA/HHS

Not risk-adjusted for this model/period.

RAF 0

ESRD/PACE

Not risk-adjusted for this model/period.

RAF 0

RXHCC

Mapped

HCC 43

Other Significant Endocrine a...

RAF 0.0

Code Trumping

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Code Book Path

Official

E83Disorders of mineral metabolism

E83.1Disorders of iron metabolism

E83.10Disorder of iron metabolism, unspecified

Inclusion Terms

Official

ICD-10-CM does not list inclusion terms for E83.10 in this effective period.

Excludes 2

Official

ICD-10-CM does not list Excludes 2 notes for E83.10 in this effective period.

Related Child Codes

Official

E83.11Hemochromatosis

E83.19Other disorders of iron metabolism

Includes

Official

ICD-10-CM does not list Includes notes for E83.10 in this effective period.

Excludes 1

Official

iron deficiency anemia (D50.-)
sideroblastic anemia (D64.0-D64.3)

Code First

Official

ICD-10-CM does not list Code First sequencing instructions for E83.10 in this effective period.

Use Additional

Official

ICD-10-CM does not list Use Additional Code instructions for E83.10 in this effective period.

Code Also

Official

ICD-10-CM does not list Code Also instructions for E83.10 in this effective period.

Buddy Documentation Tip

HCC Buddy guidance

Provider documentation confirming an iron metabolism disorder

Iron studies: serum ferritin, transferrin saturation, serum iron

Hepatic assessment if iron overload suspected

Reason for lack of specificity (workup in progress, ambiguous results)

MEAT Support

HCC Buddy guidance

Provider documentation confirming an iron metabolism disorder

Iron studies: serum ferritin, transferrin saturation, serum iron

Hepatic assessment if iron overload suspected

Reason for lack of specificity (workup in progress, ambiguous results)

Audit Caution

HCC Buddy guidance

Using E83.10 when the provider documents hemochromatosis — hemochromatosis has its own specific codes (E83.110-E83.119)

Confusing iron deficiency (too little iron) with iron metabolism disorders (usually too much or abnormal distribution)

Not recognizing that elevated ferritin alone does not confirm an iron metabolism disorder — ferritin is an acute phase reactant

Failing to query the provider when HFE genetic testing results are available but not referenced in the assessment

Common Mistakes

HCC Buddy guidance

E83.110 — Hereditary hemochromatosis: specific genetic iron overload with HFE mutation (most common: C282Y homozygosity)

E83.111 — Hemochromatosis due to repeated red blood cell transfusions: secondary/transfusional iron overload

E83.119 — Hemochromatosis, unspecified: more specific than E83.10 when hemochromatosis is confirmed but type unknown

D50.9 — Iron deficiency anemia, unspecified: LOW iron, opposite of iron overload

Last updated: FY2026 ICD-10-CM Apr update, Apr 1, 2026 through Sep 30, 2026. CMS-HCC V28 is 100% phased in for payment year 2026.

Is E83.10 an HCC code?

No. E83.10 is a billable ICD-10-CM code but does not map to any HCC category in V28, V24, ESRD, or RxHCC.

HCC Category Mapping

RxHCCHCC 43, Other Significant Endocrine and Metabolic Disorders

0.000

RAF weights shown are the community, non-dual, aged base weights from the CMS risk adjustment model file. Actual per-patient RAF contribution depends on member segment, interactions, and the model year used by the payer. V28 is the CMS-HCC model phased in over payment years 2024–2026; V24 remains in use during the transition and for historical data.

MEAT Criteria for E83.10

For E83.10to count as a valid HCC diagnosis in a given encounter, the provider's documentation must show MEAT: Monitor, Evaluate, Assess, or Treat. A diagnosis from a prior year does not carry forward automatically, it has to be re-documented and supported each calendar year.

MMonitor: signs, symptoms, disease progression, or lab trending documented in the note
EEvaluate: test results, medication response, or physical findings reviewed by the provider
AAssess: explicit mention in the assessment or plan with acknowledgment of status
TTreat: medication, referral, procedure, therapy, or counseling tied to the diagnosis

Only one of M/E/A/T is required to support the code, but the documentation must be specific enough to show that the provider actually addressed E83.10 during that encounter, not just copy-forwarded from a problem list.

Coder workflow notes

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What This Code Means

E83.10 is the ICD-10-CM diagnosis code for disorder of iron metabolism, unspecified. A metabolic disorder affecting iron levels in the body where the specific type or cause has not been identified. E83.10 sits in the ICD-10-CM chapter for endocrine, nutritional and metabolic diseases (e00-e89), within the section covering metabolic disorders (e70-e88).

E83.10 is a billable ICD-10-CM code but does not map to a payment HCC under the CMS-HCC V28, V24, ESRD, or RxHCC risk adjustment models. It can be reported on Medicare Advantage encounter data submissions but it does not contribute to a beneficiary's RAF score and therefore does not affect risk-adjusted payments to the plan.

E83.10 maps only to RxHCC 43 (Inflammatory Bowel Disease) with no RAF weight. It does NOT map to any V24 or V28 CMS-HCC, meaning it has zero impact on Medicare Advantage RAF scores. This is noteworthy because iron overload conditions can be clinically significant but are not captured as risk adjustors.

HCC Buddy maintains structured V28 and V24 mapping, RAF weights, and MEAT documentation criteria for E83.10 sourced directly from the CMS-HCC risk adjustment model files and the CMS ICD-10-CM code set.

Coding Tips

•This is a non-specific code; attempt to identify whether the disorder is hemochromatosis, iron deficiency, or another specific iron metabolism condition
•Review for more specific iron metabolism codes (E83.11 for hemochromatosis) before using this unspecified code

Clinical Significance

Disorder of iron metabolism, unspecified covers confirmed iron metabolism disorders without specification of the type. This may represent hemochromatosis, iron loading disorders, or other iron metabolism abnormalities pending further diagnostic characterization. Iron overload can cause liver disease, cardiomyopathy, diabetes, and endocrine dysfunction if untreated.

Documentation Requirements

✓Provider documentation confirming an iron metabolism disorder
✓Iron studies: serum ferritin, transferrin saturation, serum iron
✓Hepatic assessment if iron overload suspected
✓Reason for lack of specificity (workup in progress, ambiguous results)
✓Genetic testing status for hereditary hemochromatosis (HFE gene)
✓Plan for further diagnostic evaluation or therapeutic phlebotomy

Commonly Confused Codes

•E83.110: Hereditary hemochromatosis: specific genetic iron overload with HFE mutation (most common: C282Y homozygosity)
•E83.111: Hemochromatosis due to repeated red blood cell transfusions: secondary/transfusional iron overload
•E83.119: Hemochromatosis, unspecified: more specific than E83.10 when hemochromatosis is confirmed but type unknown
•D50.9: Iron deficiency anemia, unspecified: LOW iron, opposite of iron overload
•E61.1: Iron deficiency: nutritional iron deficiency, not a metabolism disorder