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E77.9 ICD-10-CM Code: Disorder of glycoprotein metabolism, unspecified

ICD-10-CM Code View

HCC Buddy Code Card

Digital ICD-10 code-book layout with official code detail, always-visible risk models, Code Trumping, and Buddy coding guidance.

FY 2026 Apr update / Endocrine, nutritional and metabolic diseases (E00-E89) / Metabolic disorders (E70-E88)

E77.9

Billable / SpecificICD-10-CMOfficial ICD-10-CMCodebook guidance

Disorder of glycoprotein metabolism, unspecified

A metabolic disorder affecting glycoprotein processing in the body, but the specific type has not been determined or specified.

Buddy the Bee presenting code insight

Buddy Insight

Disorder of glycoprotein metabolism, unspecified indicates a confirmed glycoprotein metabolism problem without sufficient documentation to assign a specific code.

CMS-HCC V28

0

0

RAF 0

CMS-HCC V24

HCC 23

RAF 0.230

ACA/HHS

0

0

RAF 0

ESRD/PACE

HCC 23

RAF 0.0

RXHCC

HCC 43

RAF 0.0

Code Trumping

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Code Book Path

Official
E77Disorders of glycoprotein metabolism
E77.9Disorder of glycoprotein metabolism, unspecified

Inclusion Terms

Official

ICD-10-CM does not list inclusion terms for E77.9 in this effective period.

Excludes 2

Official

ICD-10-CM does not list Excludes 2 notes for E77.9 in this effective period.

Related Child Codes

Official
E77.0Defects in post-translational modification of lysosomal enzymes
E77.1Defects in glycoprotein degradation
E77.8Other disorders of glycoprotein metabolism

Includes

Official

ICD-10-CM does not list Includes notes for E77.9 in this effective period.

Excludes 1

Official

ICD-10-CM does not list Excludes 1 notes for E77.9 in this effective period.

Code First

Official

ICD-10-CM does not list Code First sequencing instructions for E77.9 in this effective period.

Use Additional

Official

ICD-10-CM does not list Use Additional Code instructions for E77.9 in this effective period.

Code Also

Official

ICD-10-CM does not list Code Also instructions for E77.9 in this effective period.

Buddy Documentation Tip

HCC Buddy guidance
Provider documentation confirming a glycoprotein metabolism disorder
Clinical evidence supporting the diagnosis (abnormal glycoprotein levels, clinical features)
Reason specificity is lacking (workup in progress, indeterminate results)
Plan for further diagnostic evaluation

MEAT Support

HCC Buddy guidance
Provider documentation confirming a glycoprotein metabolism disorder
Clinical evidence supporting the diagnosis (abnormal glycoprotein levels, clinical features)
Reason specificity is lacking (workup in progress, indeterminate results)
Plan for further diagnostic evaluation

Audit Caution

HCC Buddy guidance
Accepting unspecified code when diagnostic results in the chart would support a specific glycoprotein disorder code
Not querying the provider when enzyme studies or genetic test results are available
Confusing glycoprotein disorders with glycolipid (sphingolipid) or glycogen storage disorders
Using this code as a final diagnosis without plan for further specification

Common Mistakes

HCC Buddy guidance
E77.0 — Defects in post-translational modification: for mucolipidoses (I-cell disease, pseudo-Hurler polydystrophy)
E77.1 — Defects in glycoprotein degradation: for mannosidosis, fucosidosis, sialidosis
E77.8 — Other disorders of glycoprotein metabolism: for CDG and other specified conditions
E88.9 — Metabolic disorder, unspecified: too broad when glycoprotein involvement is confirmed

Last updated: FY2026 ICD-10-CM Apr update, Apr 1, 2026 through Sep 30, 2026. CMS-HCC V28 is 100% phased in for payment year 2026.

Is E77.9 an HCC code?

Yes. E77.9 maps to Other Significant Endocrine and Metabolic Disorders under the V24 model but is not retained in V28.

HCC Category Mapping

V24HCC 23, Other Significant Endocrine and Metabolic Disorders
0.230
ESRDHCC 23, Other Significant Endocrine and Metabolic Disorders
0.000
RxHCCHCC 43, Other Significant Endocrine and Metabolic Disorders
0.000

RAF weights shown are the community, non-dual, aged base weights from the CMS risk adjustment model file. Actual per-patient RAF contribution depends on member segment, interactions, and the model year used by the payer. V28 is the CMS-HCC model phased in over payment years 2024–2026; V24 remains in use during the transition and for historical data.

MEAT Criteria for E77.9

For E77.9to count as a valid HCC diagnosis in a given encounter, the provider's documentation must show MEAT: Monitor, Evaluate, Assess, or Treat. A diagnosis from a prior year does not carry forward automatically, it has to be re-documented and supported each calendar year.

  • MMonitor: signs, symptoms, disease progression, or lab trending documented in the note
  • EEvaluate: test results, medication response, or physical findings reviewed by the provider
  • AAssess: explicit mention in the assessment or plan with acknowledgment of status
  • TTreat: medication, referral, procedure, therapy, or counseling tied to the diagnosis

Only one of M/E/A/T is required to support the code, but the documentation must be specific enough to show that the provider actually addressed E77.9 during that encounter, not just copy-forwarded from a problem list.

What This Code Means

E77.9 is the ICD-10-CM diagnosis code for disorder of glycoprotein metabolism, unspecified. A metabolic disorder affecting glycoprotein processing in the body, but the specific type has not been determined or specified. E77.9 sits in the ICD-10-CM chapter for endocrine, nutritional and metabolic diseases (e00-e89), within the section covering metabolic disorders (e70-e88).

Under the older CMS-HCC V24 model, E77.9 maps to Other Significant Endocrine and Metabolic Disorders (HCC 23) with a community, non-dual, aged base RAF weight of 0.230. V28 is the CMS-HCC risk adjustment model that reached 100% phase-in for payment year 2026, replacing V24 which was used during the PY2024–PY2025 transition.

This is a catch-all code; attempt to obtain more specific diagnosis before coding. Because E77.9 maps to a payment HCC, the provider's documentation must satisfy MEAT criteria (Monitor, Evaluate, Assess, or Treat) for the encounter to count toward the patient's Medicare Advantage risk adjustment score. When documentation is ambiguous, coders should issue a provider query rather than assume the highest-specificity variant.

HCC Buddy maintains structured V28 and V24 mapping, RAF weights, and MEAT documentation criteria for E77.9 sourced directly from the CMS-HCC risk adjustment model files and the CMS ICD-10-CM code set.

Coding Tips

  • This is a catch-all code; attempt to obtain more specific diagnosis before coding
  • Query provider if additional testing or clinical findings could clarify the specific glycoprotein disorder

Clinical Significance

Disorder of glycoprotein metabolism, unspecified indicates a confirmed glycoprotein metabolism problem without sufficient documentation to assign a specific code. This code should prompt queries for additional diagnostic detail since glycoprotein disorders vary widely in severity and treatment needs.

Documentation Requirements

  • Provider documentation confirming a glycoprotein metabolism disorder
  • Clinical evidence supporting the diagnosis (abnormal glycoprotein levels, clinical features)
  • Reason specificity is lacking (workup in progress, indeterminate results)
  • Plan for further diagnostic evaluation
  • Current symptom management and follow-up

Commonly Confused Codes

  • E77.0: Defects in post-translational modification: for mucolipidoses (I-cell disease, pseudo-Hurler polydystrophy)
  • E77.1: Defects in glycoprotein degradation: for mannosidosis, fucosidosis, sialidosis
  • E77.8: Other disorders of glycoprotein metabolism: for CDG and other specified conditions
  • E88.9: Metabolic disorder, unspecified: too broad when glycoprotein involvement is confirmed

Child Codes

Code Hierarchy

Because E77.9 maps to a payment HCC, the documentation must also satisfy MEAT criteria (Monitor, Evaluate, Assess, or Treat) for the encounter to count toward the patient's risk adjustment score.

Work E77.9 in HCC Buddy

Open E77.9 in the Code Book for the full Index-to-Tabular path, MEAT checklist, and V28 HCC mapping, or in the Encoder to code from a keyword search. Pro includes 14 days to try everything.