E77.8
BillableOther disorders of glycoprotein metabolism
HCC Category Mapping
V24HCC 23 — Other Significant Endocrine and Metabolic Disorders
0.230ESRDHCC 23 — Other Significant Endocrine and Metabolic Disorders
0.000RxHCCHCC 43 — Other Significant Endocrine and Metabolic Disorders
0.000What This Code Means
Other rare metabolic disorders affecting how the body processes glycoproteins that don't fit into more specific categories.
Coding Tips
- •Use this code only when the specific glycoprotein metabolism disorder is not classifiable elsewhere
- •Document the clinical presentation and any identified metabolic abnormalities
Clinical Significance
Other disorders of glycoprotein metabolism captures glycoprotein metabolism conditions not classified in E77.0 or E77.1, including congenital disorders of glycosylation (CDG) and other rare glycosylation pathway defects. These multi-system disorders can cause neurological impairment, coagulopathy, hepatic dysfunction, and growth failure.
Documentation Requirements
- ✓Specific glycoprotein metabolism disorder documented (e.g., congenital disorder of glycosylation, specific CDG type)
- ✓Confirmatory testing: isoelectric focusing of transferrin, enzyme assays, or genetic testing
- ✓Multi-system involvement assessment: neurological, hepatic, coagulation, endocrine
- ✓Current treatment plan and nutritional support needs
- ✓Provider assessment distinguishing this from conditions in E77.0 and E77.1
Commonly Confused Codes
E77.0 — Defects in post-translational modification of lysosomal enzymes: specifically for mucolipidosesE77.1 — Defects in glycoprotein degradation: for conditions like mannosidosis and fucosidosisE77.9 — Disorder of glycoprotein metabolism, unspecified: avoid when a specific disorder is documentedE74.8 — Other specified disorders of carbohydrate metabolism: CDG may overlap with carbohydrate metabolism issues
Code Hierarchy
└E77Disorders of glycoprotein metabolism└E77.8Other disorders of glycoprotein metabolism
└E77.8Other disorders of glycoprotein metabolism