E73.1 ICD-10-CM Code: Secondary lactase deficiency
E73.1 is not a CMS-HCC payment code. MEAT criteria · RAF Calculator · HCC Buddy coding tools
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FY 2026 Apr update / Endocrine, nutritional and metabolic diseases (E00-E89) / Metabolic disorders (E70-E88)
E73.1
Billable / SpecificICD-10-CMOfficial ICD-10-CMCodebook guidanceSecondary lactase deficiency
This condition occurs when the body loses its ability to produce lactase (an enzyme needed to digest milk sugar) due to another disease or condition, such as gastroenteritis or celiac disease. It's different from primary lactase deficiency, which is a natural decrease in lactase production that happens with age.
CMS-HCC V28
N/A—
Not mapped
CMS-HCC V24
HistoricalHistorical
Not used for CY2026 payment
ACA/HHS
N/A—
Not mapped
ESRD/PACE
N/A—
Not mapped
RXHCC
N/A—
Not mapped
Code Book Path
Inclusion Terms
OfficialNo inclusion terms are included in this display for E73.1. Check the code and parent instructions in the Code Book.
Excludes 2
Official- Ehlers-Danlos syndromes (Q79.6-)Inherited from E70-E88
Related Codes
Includes
OfficialNo Includes notes are included in this display for E73.1. Check the code and parent instructions in the Code Book.
Excludes 1
Official- transitory endocrine and metabolic disorders specific to newborn (P70-P74)Inherited from E00-E89, E70-E88
- androgen insensitivity syndrome (E34.5-)Inherited from E00-E89, E70-E88
- congenital adrenal hyperplasia (E25.0)Inherited from E00-E89, E70-E88
- hemolytic anemias attributable to enzyme disorders (D55.-)Inherited from E00-E89, E70-E88
- Marfan syndrome (Q87.4-)Inherited from E00-E89, E70-E88
- 5-alpha-reductase deficiency (E29.1)Inherited from E00-E89, E70-E88
Code First
OfficialNo Code First sequencing instructions are included in this display for E73.1. Check the code and parent instructions in the Code Book.
Use Additional
OfficialNo Use Additional Code instructions are included in this display for E73.1. Check the code and parent instructions in the Code Book.
Code Also
OfficialNo Code Also instructions are included in this display for E73.1. Check the code and parent instructions in the Code Book.
Buddy Documentation Tip
Current with CMS: FY2026 ICD-10-CM Apr 1 update (effective Apr 1 – Sep 30, 2026) · CMS-HCC V28, 100% phased in for payment year 2026. FY2027 code set already staged for October 1, 2026. How HCC Buddy stays current →
Is E73.1 an HCC code?
No. E73.1 is a billable ICD-10-CM code with no mapping under the current CMS-HCC V28 community payment model, and none under the ESRD, Part D RxHCC, or HHS-HCC models.
- Code
- E73.1
- Description
- Secondary lactase deficiency
- HCC (V28)
- No CMS-HCC V28 mapping
- RAF reference coefficient
- —
- Billable
- Yes
- Payment year
- 2026
Coder workflow notes
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What This Code Means
E73.1 is the ICD-10-CM diagnosis code for secondary lactase deficiency. This condition occurs when the body loses its ability to produce lactase (an enzyme needed to digest milk sugar) due to another disease or condition, such as gastroenteritis or celiac disease. It's different from primary lactase deficiency, which is a natural decrease in lactase production that happens with age. E73.1 sits in the ICD-10-CM chapter for endocrine, nutritional and metabolic diseases (e00-e89), within the section covering metabolic disorders (e70-e88).
E73.1 is a billable ICD-10-CM code, but no current CMS-HCC V28 community payment mapping is shown, and none under the ESRD, Part D RxHCC, or HHS-HCC models. Do not assign risk adjustment value from this page when no source-backed mapping is shown; verify the applicable model and payment year.
Always investigate and code the underlying cause of the lactase deficiency (such as gastroenteritis, celiac disease, or Crohn's disease) as the primary condition, with E73.1 as a secondary diagnosis.
HCC Buddy maintains structured V28 and V24 mapping, source-labeled coefficient references, and MEAT documentation criteria for E73.1 sourced directly from the CMS-HCC risk adjustment model files and the CMS ICD-10-CM code set.
Coding Tips
- •Always investigate and code the underlying cause of the lactase deficiency (such as gastroenteritis, celiac disease, or Crohn's disease) as the primary condition, with E73.1 as a secondary diagnosis
- •Distinguish between E73.0 (congenital lactase deficiency), E73.1 (secondary lactase deficiency), and E73.9 (unspecified lactase deficiency) based on the documented etiology and onset

