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E71.2 ICD-10-CM Code: Disorder of branched-chain amino-acid metabolism, unspecified

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FY 2026 Apr update / Endocrine, nutritional and metabolic diseases (E00-E89) / Metabolic disorders (E70-E88)

E71.2

Billable / SpecificICD-10-CMOfficial ICD-10-CMCodebook guidance

Disorder of branched-chain amino-acid metabolism, unspecified

A metabolic disorder affecting the breakdown of branched-chain amino acids, but the specific type has not been identified or documented.

Buddy the Bee presenting code insight

Buddy Insight

This unspecified code indicates a branched-chain amino acid metabolism disorder where the specific type has not been determined or documented, encompassing potential defects in leucine, isoleucine, or valine metabolic pathways.

CMS-HCC V28

N/A

Not mapped

CMS-HCC V24

HCC 23

RAF 0.194

ACA/HHS

HCC 28

Varies by metal level

ESRD/PACE

HCC 23

RAF 0.036

RXHCC

HCC 43

RAF 0.063

Code Book Path

Official
E71Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
E71.2Disorder of branched-chain amino-acid metabolism, unspecified

Inclusion Terms

Official

ICD-10-CM does not list inclusion terms for E71.2 in this effective period.

Excludes 2

Official

ICD-10-CM does not list Excludes 2 notes for E71.2 in this effective period.

Related Child Codes

Official
E71.0Maple-syrup-urine disease
E71.1Other disorders of branched-chain amino-acid metabolism
E71.3Disorders of fatty-acid metabolism
E71.4Disorders of carnitine metabolism
E71.5Peroxisomal disorders

Includes

Official

ICD-10-CM does not list Includes notes for E71.2 in this effective period.

Excludes 1

Official

ICD-10-CM does not list Excludes 1 notes for E71.2 in this effective period.

Code First

Official

ICD-10-CM does not list Code First sequencing instructions for E71.2 in this effective period.

Use Additional

Official

ICD-10-CM does not list Use Additional Code instructions for E71.2 in this effective period.

Code Also

Official

ICD-10-CM does not list Code Also instructions for E71.2 in this effective period.

Buddy Documentation Tip

HCC Buddy guidance
Document the clinical findings suggesting a branched-chain amino acid disorder, any available laboratory results (plasma amino acids, urine organic acids), reason why specific diagnosis has not been established, and referral to metabolic specialist if pending workup.
Query provider for additional specificity when possible.

MEAT Support

HCC Buddy guidance
Document the clinical findings suggesting a branched-chain amino acid disorder, any available laboratory results (plasma amino acids, urine organic acids), reason why specific diagnosis has not been established, and referral to metabolic specialist if pending workup.
Query provider for additional specificity when possible.

Audit Caution

HCC Buddy guidance
This unspecified code should be a last resort.
Always query the provider for more specific documentation before assigning this code.
Medical necessity may be questioned with unspecified metabolic disorder codes.

Common Mistakes

HCC Buddy guidance
E71.19 (Other disorders of branched-chain amino-acid metabolism) which is the 'other specified' code when a disorder is identified but not specifically coded
E71.0 (Maple-syrup-urine disease) which is a specific branched-chain disorder
E71.111-E71.128 for specific organic acidurias.

Last updated: FY2026 ICD-10-CM Apr update, Apr 1, 2026 through Sep 30, 2026. CMS-HCC V28 is 100% phased in for payment year 2026.

Is E71.2 an HCC code?

Yes. E71.2 maps to Other Significant Endocrine and Metabolic Disorders under the V24 model but is not retained in V28.

Code
E71.2
Description
Disorder of branched-chain amino-acid metabolism, unspecified
HCC (V28)
No CMS-HCC V28 mapping
RAF
Billable
Yes
Payment year
2026

HCC Category Mapping

V24HCC 23, Other Significant Endocrine and Metabolic Disorders
0.194
ESRDHCC 23, Other Significant Endocrine and Metabolic Disorders
0.036
RxHCCHCC 43, Other Significant Endocrine and Metabolic Disorders
0.063

Each model's RAF is its CMS base weight for that model's standard population, so weights are not directly comparable across models: CMS-HCC V28 and V24 use Community, Non-Dual, Aged; ESRD uses the dialysis continuing-enrollee model; RxHCC is the Part D continuing-enrollee, non-low-income, aged weight (a larger scale than CMS-HCC). ACA/HHS has no single weight — it varies by metal level. Actual per-patient RAF contribution depends on member segment, interactions, and the model year used by the payer. V28 is the CMS-HCC model phased in over payment years 2024–2026; V24 remains in use during the transition and for historical data.

Work E71.2 in the Code Book — tabular path, V28 RAF, and MEAT checklist →

MEAT Criteria for E71.2

For E71.2to count as a valid HCC diagnosis in a given encounter, the provider's documentation must show MEAT: Monitor, Evaluate, Assess, or Treat. A diagnosis from a prior year does not carry forward automatically, it has to be re-documented and supported each calendar year.

  • MMonitor: signs, symptoms, disease progression, or lab trending documented in the note
  • EEvaluate: test results, medication response, or physical findings reviewed by the provider
  • AAssess: explicit mention in the assessment or plan with acknowledgment of status
  • TTreat: medication, referral, procedure, therapy, or counseling tied to the diagnosis

Only one of M/E/A/T is required to support the code, but the documentation must be specific enough to show that the provider actually addressed E71.2 during that encounter, not just copy-forwarded from a problem list.

Coder workflow notes

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What This Code Means

E71.2 is the ICD-10-CM diagnosis code for disorder of branched-chain amino-acid metabolism, unspecified. A metabolic disorder affecting the breakdown of branched-chain amino acids, but the specific type has not been identified or documented. E71.2 sits in the ICD-10-CM chapter for endocrine, nutritional and metabolic diseases (e00-e89), within the section covering metabolic disorders (e70-e88).

Under the older CMS-HCC V24 model, E71.2 maps to Other Significant Endocrine and Metabolic Disorders (HCC 23) with a community, non-dual, aged base RAF weight of 0.194. V28 is the CMS-HCC risk adjustment model that reached 100% phase-in for payment year 2026, replacing V24 which was used during the PY2024–PY2025 transition.

This is an unspecified code; use only when the specific type of branched-chain disorder cannot be determined. Because E71.2 maps to a payment HCC, the provider's documentation must satisfy MEAT criteria (Monitor, Evaluate, Assess, or Treat) for the encounter to count toward the patient's Medicare Advantage risk adjustment score. When documentation is ambiguous, coders should issue a provider query rather than assume the highest-specificity variant.

HCC Buddy maintains structured V28 and V24 mapping, RAF weights, and MEAT documentation criteria for E71.2 sourced directly from the CMS-HCC risk adjustment model files and the CMS ICD-10-CM code set.

Coding Tips

  • This is an unspecified code; use only when the specific type of branched-chain disorder cannot be determined
  • Query the provider if more specific documentation is available to assign a more precise code

Clinical Significance

This unspecified code indicates a branched-chain amino acid metabolism disorder where the specific type has not been determined or documented, encompassing potential defects in leucine, isoleucine, or valine metabolic pathways. While it captures the condition for risk adjustment purposes, it represents an opportunity for improved diagnostic specificity. These disorders generally require metabolic specialist involvement and dietary management.

Documentation Requirements

  • Document the clinical findings suggesting a branched-chain amino acid disorder, any available laboratory results (plasma amino acids, urine organic acids), reason why specific diagnosis has not been established, and referral to metabolic specialist if pending workup.
  • Query provider for additional specificity when possible.

Commonly Confused Codes

  • E71.19 (Other disorders of branched-chain amino-acid metabolism) which is the 'other specified' code when a disorder is identified but not specifically coded
  • E71.0 (Maple-syrup-urine disease) which is a specific branched-chain disorder
  • E71.111-E71.128 for specific organic acidurias.

Child Codes

Code Hierarchy

Because E71.2 maps to a payment HCC, the documentation must also satisfy MEAT criteria (Monitor, Evaluate, Assess, or Treat) for the encounter to count toward the patient's risk adjustment score.

Work E71.2 in HCC Buddy

Open E71.2 in the Code Book for the full Index-to-Tabular path, MEAT checklist, and V28 HCC mapping, or in the Encoder to code from a keyword search. Pro includes 7 days to try everything, no card required.