E70.328

HCC Category Mapping

What This Code Means

This code describes a rare form of albinism that affects both the skin and eyes, causing reduced pigmentation in these areas. It is a genetic condition where the body cannot properly produce or distribute melanin, the pigment responsible for skin and eye color.

Coding Tips

• •Verify the specific type of oculocutaneous albinism documented by the provider, as codes E70.320-E70.329 distinguish between different subtypes; E70.328 is used when the type doesn't fit other specified categories
• •Ensure documentation clearly indicates involvement of both eyes and skin; if only one system is affected, a different albinism code may be more appropriate

Clinical Significance

Other oculocutaneous albinism captures rare subtypes beyond the classic tyrosinase-negative and tyrosinase-positive forms, including Types 3 (TYRP1 mutations, more common in individuals of African descent) and Type 4 (SLC45A2 mutations). These forms vary in severity of pigment reduction and associated visual impairment, and proper subtype identification is important for genetic counseling and management optimization.

Documentation Requirements

• ✓Documentation should specify the genetic mutation or clinical subtype identified, detailed pigmentation assessment of skin, hair, and eyes, ophthalmologic examination findings, and genetic counseling records.
• ✓The provider should document why this case does not fit the tyrosinase-negative or tyrosinase-positive categories.
• ✓Family history and inheritance pattern analysis should be included.

Commonly Confused Codes