E50.4 ICD-10-CM Code: Vitamin A deficiency with keratomalacia
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FY 2026 Apr update / Endocrine, nutritional and metabolic diseases (E00-E89) / Other nutritional deficiencies (E50-E64)
E50.4
Billable / SpecificICD-10-CMOfficial ICD-10-CMCodebook guidanceVitamin A deficiency with keratomalacia
Vitamin A deficiency causing softening and melting of the cornea, a serious eye condition that can rapidly lead to blindness if not treated immediately.
CMS-HCC V28
N/A—
Not mapped
CMS-HCC V24
N/A—
Not mapped
ACA/HHS
N/A—
Not mapped
ESRD/PACE
N/A—
Not mapped
RXHCC
N/A—
Not mapped
Code Book Path
Inclusion Terms
OfficialICD-10-CM does not list inclusion terms for E50.4 in this effective period.
Excludes 2
OfficialICD-10-CM does not list Excludes 2 notes for E50.4 in this effective period.
Related Child Codes
Includes
OfficialICD-10-CM does not list Includes notes for E50.4 in this effective period.
Excludes 1
Official- sequelae of vitamin A deficiency (E64.1)
Code First
OfficialICD-10-CM does not list Code First sequencing instructions for E50.4 in this effective period.
Use Additional
OfficialICD-10-CM does not list Use Additional Code instructions for E50.4 in this effective period.
Code Also
OfficialICD-10-CM does not list Code Also instructions for E50.4 in this effective period.
Buddy Documentation Tip
Current with CMS: FY2026 ICD-10-CM Apr 1 update (effective Apr 1 – Sep 30, 2026) · CMS-HCC V28, 100% phased in for payment year 2026. FY2027 code set already staged for October 1, 2026. How HCC Buddy stays current →
Is E50.4 an HCC code?
No. E50.4 is a billable ICD-10-CM code but does not map to any HCC category in V28, V24, ESRD, or RxHCC.
- Code
- E50.4
- Description
- Vitamin A deficiency with keratomalacia
- HCC (V28)
- No CMS-HCC V28 mapping
- RAF
- —
- Billable
- Yes
- Payment year
- 2026
Coder workflow notes
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This code does not map to an HCC category in any model (V28, V24, ESRD, RxHCC).
What This Code Means
E50.4 is the ICD-10-CM diagnosis code for vitamin a deficiency with keratomalacia. Vitamin A deficiency causing softening and melting of the cornea, a serious eye condition that can rapidly lead to blindness if not treated immediately. E50.4 sits in the ICD-10-CM chapter for endocrine, nutritional and metabolic diseases (e00-e89), within the section covering other nutritional deficiencies (e50-e64).
E50.4 is a billable ICD-10-CM code but does not map to a payment HCC under the CMS-HCC V28, V24, ESRD, or RxHCC risk adjustment models. It can be reported on Medicare Advantage encounter data submissions but it does not contribute to a beneficiary's RAF score and therefore does not affect risk-adjusted payments to the plan.
Keratomalacia is the most severe form of xerophthalmia and represents an ophthalmologic emergency.
HCC Buddy maintains structured V28 and V24 mapping, RAF weights, and MEAT documentation criteria for E50.4 sourced directly from the CMS-HCC risk adjustment model files and the CMS ICD-10-CM code set.
Coding Tips
- •Keratomalacia is the most severe form of xerophthalmia and represents an ophthalmologic emergency
- •This condition requires urgent vitamin A supplementation to prevent permanent blindness