E31.9

HCC Category Mapping

What This Code Means

A condition affecting multiple hormone-producing glands, but the specific type or nature of the dysfunction is not documented.

Coding Tips

• •This is a non-specific code; query the provider for more detailed documentation to assign a more specific E31 code
• •Review lab results and clinical presentation to determine if a more specific diagnosis code applies

Clinical Significance

Polyglandular dysfunction involves failure or dysfunction of multiple endocrine glands simultaneously, leading to complex hormonal imbalances that can affect metabolism, growth, reproduction, and stress response. This unspecified code signals that the provider has identified multi-gland involvement but has not specified the exact syndrome or pattern, which is critical for accurate risk adjustment and treatment planning.

Documentation Requirements

• ✓Documentation must identify which endocrine glands are affected (adrenal, thyroid, parathyroid, gonadal, pancreatic) and the specific dysfunctions present.
• ✓Lab values including hormone levels (cortisol, thyroid-stimulating hormone, parathyroid hormone, insulin, sex hormones) should be recorded.
• ✓The provider should specify if this represents an autoimmune polyglandular syndrome (Type I, II, or III) to enable assignment of a more specific code.

Commonly Confused Codes