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E31.8 ICD-10-CM Code: Other polyglandular dysfunction

E31.8 maps to CMS-HCC V28 51. A source-labeled RAF reference is available. Confirm the documented diagnosis and applicable coding requirements. MEAT criteria · RAF Calculator · HCC coding software

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Code lookupE31.8

FY 2026 Apr update / Endocrine, nutritional and metabolic diseases (E00-E89) / Disorders of other endocrine glands (E20-E35)

E31.8

Billable / SpecificICD-10-CMOfficial ICD-10-CMCodebook guidance

Other polyglandular dysfunction

A condition affecting multiple glands in the endocrine system that does not fit into other specific polyglandular dysfunction categories.

Buddy the Bee presenting code insight

Buddy Insight

Other polyglandular dysfunction captures multiple endocrine gland disorders that do not fit into autoimmune polyglandular failure, polyglandular hyperfunction, or multiple endocrine neoplasia categories.

CMS-HCC V28

HCC 51

Coefficient HCC 51: 0.510 (Community Non-Dual Aged (CNA))

CMS-HCC V24

Historical

Historical

Not used for CY2026 payment

ACA/HHS

HCC 030

Code-level coefficient reference

ESRD/PACE

HCC 23

Code-level coefficient reference

RXHCC

HCC 43

Code-level coefficient reference

Inclusion Terms

Official

No inclusion terms are included in this display for E31.8. Check the code and parent instructions in the Code Book.

Excludes 2

Official

No Excludes 2 notes are included in this display for E31.8. Check the code and parent instructions in the Code Book.

Includes

Official

No Includes notes are included in this display for E31.8. Check the code and parent instructions in the Code Book.

Excludes 1

Official
  • transitory endocrine and metabolic disorders specific to newborn (P70-P74)Inherited from E00-E89, E20-E35, E31
  • galactorrhea (N64.3)Inherited from E00-E89, E20-E35, E31
  • gynecomastia (N62)Inherited from E00-E89, E20-E35, E31
  • ataxia telangiectasia [Louis-Bar] (G11.3)Inherited from E00-E89, E20-E35, E31
  • dystrophia myotonica [Steinert] (G71.11)Inherited from E00-E89, E20-E35, E31
  • pseudohypoparathyroidism (E20.1)Inherited from E00-E89, E20-E35, E31

Code First

Official

No Code First sequencing instructions are included in this display for E31.8. Check the code and parent instructions in the Code Book.

Use Additional

Official

No Use Additional Code instructions are included in this display for E31.8. Check the code and parent instructions in the Code Book.

Code Also

Official

No Code Also instructions are included in this display for E31.8. Check the code and parent instructions in the Code Book.

Buddy Documentation Tip

HCC Buddy guidance
Document which specific glands are dysfunctional, the underlying etiology linking the polyglandular involvement, individual hormone levels for each affected gland, treatment for each component, and the reasoning for classifying under this residual category.

MEAT Support

HCC Buddy guidance
Document which specific glands are dysfunctional, the underlying etiology linking the polyglandular involvement, individual hormone levels for each affected gland, treatment for each component, and the reasoning for classifying under this residual category.

Audit Caution

HCC Buddy guidance
Ensure the documentation supports true polyglandular dysfunction rather than coincidental multiple single-gland disorders. If the dysfunction is autoimmune-mediated, use E31.
If due to tumors in multiple glands, consider multiple endocrine neoplasia codes. Code each individual gland disorder separately.

Common Mistakes

HCC Buddy guidance
E31.0 (autoimmune polyglandular failure with documented autoimmune etiology), E31.1 (polyglandular hyperfunction), E31.2x (multiple endocrine neoplasia syndromes), E89.x (postprocedural endocrine disorders if due to surgery/radiation).

Current with CMS: FY2026 ICD-10-CM Apr 1 update (effective Apr 1 – Sep 30, 2026) · CMS-HCC V28, 100% phased in for payment year 2026. FY2027 code set already staged for October 1, 2026. How HCC Buddy stays current →

Is E31.8 an HCC code?

Yes. E31.8 (Other polyglandular dysfunction) maps to HCC 51, Addison's and Cushing's Diseases, Acromegaly, and Other Specified Endocrine Disorders under the CMS-HCC V28 risk adjustment model, with a source-labeled community non-dual aged reference coefficient of 0.510. Source-labeled code-level coefficients are references, not member totals. Actual contribution depends on complete member context, hierarchy and cleanup rules, interactions, and model year. HCC Buddy's RAF Calculator supports CMS-HCC V28 PY2026 and shows no score unless every required source and calculation check passes. It is billable for payment year 2026.

Coder answer: E31.8 is billable and maps to V28 HCC 51, Addison's and Cushing's Diseases, Acromegaly, and Other Specified Endocrine Disorders. Open it in the Code Book for the tabular path, RAF, and MEAT checklist.

Code
E31.8
Description
Other polyglandular dysfunction
HCC (V28)
HCC 51 — Addison's and Cushing's Diseases, Acromegaly, and Other Specified Endocrine Disorders
RAF reference coefficient
0.510
Billable
Yes
Payment year
2026

HCC Category Mapping

V28HCC 51, Addison's and Cushing's Diseases, Acromegaly, and Other Specified Endocrine Disorders
0.510
ESRDHCC 23, Other Significant Endocrine and Metabolic Disorders
Not separately weighted
RxHCCHCC 43, Pituitary, Adrenal Gland, and Other Endocrine and Metabolic Disorders
Not separately weighted

These are source-labeled model coefficients, not member totals. A category may still be removed by hierarchy or model cleanup rules. Weights are not directly comparable across models: CMS-HCC V28 and V24 use Community, Non-Dual, Aged; ESRD uses the dialysis continuing-enrollee model; RxHCC is the Part D continuing-enrollee, non-low-income, aged weight (a larger scale than CMS-HCC). ACA/HHS has no single weight — it varies by metal level. Actual per-patient RAF contribution depends on member context, hierarchy and cleanup rules, interactions, and the model year used by the payer. V28 is the CMS-HCC model phased in over payment years 2024–2026; V24 remains available for historical review.

Work E31.8 in the Code Book — tabular path, V28 RAF reference, and MEAT checklist →

MEAT review for E31.8

For E31.8, confirm that the documentation supports the diagnosis and meets the applicable coding, encounter, program and payer requirements. MEAT (Monitor, Evaluate, Assess, or Treat) is a review mnemonic, not a universal CMS coding rule.

  • MMonitor: signs, symptoms, disease progression, or lab trending documented in the note
  • EEvaluate: test results, medication response, or physical findings reviewed by the provider
  • AAssess: explicit mention in the assessment or plan with acknowledgment of status
  • TTreat: medication, referral, procedure, therapy, or counseling tied to the diagnosis

Coder workflow notes

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What This Code Means

E31.8 is the ICD-10-CM diagnosis code for other polyglandular dysfunction. A condition affecting multiple glands in the endocrine system that does not fit into other specific polyglandular dysfunction categories. E31.8 sits in the ICD-10-CM chapter for endocrine, nutritional and metabolic diseases (e00-e89), within the section covering disorders of other endocrine glands (e20-e35).

Under the CMS-HCC V28 risk adjustment model, E31.8 maps to Addison's and Cushing's Diseases, Acromegaly, and Other Specified Endocrine Disorders (HCC 51) with a source-labeled community, non-dual, aged reference coefficient of 0.510. No V24 mapping is shown for E31.8; use the applicable model and payment year when reviewing the V28 mapping. For CY2026 non-PACE Medicare Advantage, CMS uses 100% of the 2024 CMS-HCC model (V28). PACE uses a separate model blend. Source-labeled code-level coefficients are references, not member totals. Actual contribution depends on complete member context, hierarchy and cleanup rules, interactions, and model year. HCC Buddy's RAF Calculator supports CMS-HCC V28 PY2026 and shows no score unless every required source and calculation check passes.

Use this code for rare or atypical presentations of multiple gland dysfunction. For E31.8, confirm that the documentation supports the diagnosis and meets the applicable coding, encounter, program and payer requirements. MEAT (Monitor, Evaluate, Assess, or Treat) is a review mnemonic, not a universal CMS coding rule. When documentation is ambiguous, coders should issue a provider query rather than assume the highest-specificity variant.

HCC Buddy maintains structured V28 and V24 mapping, source-labeled coefficient references, and MEAT documentation criteria for E31.8 sourced directly from the CMS-HCC risk adjustment model files and the CMS ICD-10-CM code set.

Coding Tips

  • Use this code for rare or atypical presentations of multiple gland dysfunction
  • Document the specific glands involved and their dysfunction to support medical necessity

Clinical Significance

Other polyglandular dysfunction captures multiple endocrine gland disorders that do not fit into autoimmune polyglandular failure, polyglandular hyperfunction, or multiple endocrine neoplasia categories. This includes rare combined endocrinopathies from non-autoimmune causes such as infiltrative diseases, radiation effects on multiple glands, or other uncommon etiologies.

Documentation Requirements

  • Document which specific glands are dysfunctional, the underlying etiology linking the polyglandular involvement, individual hormone levels for each affected gland, treatment for each component, and the reasoning for classifying under this residual category.

Commonly Confused Codes

  • E31.0 (autoimmune polyglandular failure with documented autoimmune etiology), E31.1 (polyglandular hyperfunction), E31.2x (multiple endocrine neoplasia syndromes), E89.x (postprocedural endocrine disorders if due to surgery/radiation).

Child Codes

Code Hierarchy

Also searched as

  • E31 8
  • E318

For E31.8, confirm that the documentation supports the diagnosis and meets the applicable coding, encounter, program and payer requirements. MEAT (Monitor, Evaluate, Assess, or Treat) is a review mnemonic, not a universal CMS coding rule.

E31.8 maps to CMS-HCC V28 category 51, Addison's and Cushing's Diseases, Acromegaly, and Other Specified Endocrine Disorders. See the ICD-10 to HCC mapping hub for how the V28 crosswalk works. The mapping identifies a payment HCC category for E31.8. Review its source-labeled HCC coefficient above, check the RAF Calculator with complete member context for CMS-HCC V28 PY2026, and confirm the documentation the chart needs before the code is submitted. HCC Buddy shows no RAF score unless every required source and calculation check passes.

Work E31.8 in HCC Buddy

Open E31.8 in the Code Book for the full Index-to-Tabular path, MEAT checklist, and V28 HCC mapping, or in the Encoder to code from a keyword search. Pro includes 7 days to try everything, no card required.