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E28.310 ICD-10-CM Code: Symptomatic premature menopause

E28.310 is not a CMS-HCC payment code. MEAT criteria · RAF calculator · HCC Buddy coding tools

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FY 2026 Apr update / Endocrine, nutritional and metabolic diseases (E00-E89) / Disorders of other endocrine glands (E20-E35)

E28.310

Billable / SpecificICD-10-CMOfficial ICD-10-CMCodebook guidance

Symptomatic premature menopause

Early menopause occurring before age 40 with noticeable symptoms such as hot flashes, night sweats, or mood changes.

CMS-HCC V28

N/A

Not mapped

CMS-HCC V24

N/A

Not mapped

ACA/HHS

N/A

Not mapped

ESRD/PACE

N/A

Not mapped

RXHCC

N/A

Not mapped

Code Book Path

Official
E28.3Primary ovarian failure
E28.31Premature menopause
E28.310Symptomatic premature menopause

Inclusion Terms

Official
  • Symptoms such as flushing, sleeplessness, headache, lack of concentration, associated with premature menopause

Excludes 2

Official

ICD-10-CM does not list Excludes 2 notes for E28.310 in this effective period.

Related Child Codes

Official
E28.319Asymptomatic premature menopause

Includes

Official

ICD-10-CM does not list Includes notes for E28.310 in this effective period.

Excludes 1

Official

ICD-10-CM does not list Excludes 1 notes for E28.310 in this effective period.

Code First

Official

ICD-10-CM does not list Code First sequencing instructions for E28.310 in this effective period.

Use Additional

Official

ICD-10-CM does not list Use Additional Code instructions for E28.310 in this effective period.

Code Also

Official

ICD-10-CM does not list Code Also instructions for E28.310 in this effective period.

Buddy Documentation Tip

HCC Buddy guidance
Document the specific symptoms the patient is experiencing to support medical necessity for treatment
Distinguish from asymptomatic premature menopause (E28.319) which requires different coding

Current with CMS: FY2026 ICD-10-CM Apr 1 update (effective Apr 1 – Sep 30, 2026) · CMS-HCC V28, 100% phased in for payment year 2026. FY2027 code set already staged for October 1, 2026. How HCC Buddy stays current →

Is E28.310 an HCC code?

No. E28.310 is a billable ICD-10-CM code but does not map to any HCC category in V28, V24, ESRD, or RxHCC.

Code
E28.310
Description
Symptomatic premature menopause
HCC (V28)
No CMS-HCC V28 mapping
RAF
Billable
Yes
Payment year
2026

Coder workflow notes

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This code does not map to an HCC category in any model (V28, V24, ESRD, RxHCC).

What This Code Means

E28.310 is the ICD-10-CM diagnosis code for symptomatic premature menopause. Early menopause occurring before age 40 with noticeable symptoms such as hot flashes, night sweats, or mood changes. E28.310 sits in the ICD-10-CM chapter for endocrine, nutritional and metabolic diseases (e00-e89), within the section covering disorders of other endocrine glands (e20-e35).

E28.310 is a billable ICD-10-CM code but does not map to a payment HCC under the CMS-HCC V28, V24, ESRD, or RxHCC risk adjustment models. It can be reported on Medicare Advantage encounter data submissions but it does not contribute to a beneficiary's RAF score and therefore does not affect risk-adjusted payments to the plan.

Document the specific symptoms the patient is experiencing to support medical necessity for treatment.

HCC Buddy maintains structured V28 and V24 mapping, RAF weights, and MEAT documentation criteria for E28.310 sourced directly from the CMS-HCC risk adjustment model files and the CMS ICD-10-CM code set.

Coding Tips

  • Document the specific symptoms the patient is experiencing to support medical necessity for treatment
  • Distinguish from asymptomatic premature menopause (E28.319) which requires different coding

Child Codes

Code Hierarchy

Work E28.310 in HCC Buddy

Open E28.310 in the Code Book for the full Index-to-Tabular path, MEAT checklist, and V28 HCC mapping, or in the Encoder to code from a keyword search. Pro includes 7 days to try everything, no card required.