E16.0 ICD-10-CM Code: Drug-induced hypoglycemia without coma
E16.0 is not a CMS-HCC payment code. MEAT criteria · RAF Calculator · free HCC coding tools
HCC Buddy Code Card
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FY 2026 Apr update / Endocrine, nutritional and metabolic diseases (E00-E89) / Other disorders of glucose regulation and pancreatic internal secretion (E15-E16)
E16.0
Billable / SpecificICD-10-CMOfficial ICD-10-CMCodebook guidanceDrug-induced hypoglycemia without coma
Low blood sugar caused by medication or drugs, but the patient is conscious and alert.
CMS-HCC V28
N/A—
Not mapped
CMS-HCC V24
HistoricalHistorical
Not used for CY2026 payment
ACA/HHS
N/A—
Not mapped
ESRD/PACE
N/A—
Not mapped
RXHCC
N/A—
Not mapped
Code Book Path
Inclusion Terms
OfficialNo inclusion terms are included in this display for E16.0. Check the code and parent instructions in the Code Book.
Excludes 2
OfficialNo Excludes 2 notes are included in this display for E16.0. Check the code and parent instructions in the Code Book.
Related Codes
Includes
OfficialNo Includes notes are included in this display for E16.0. Check the code and parent instructions in the Code Book.
Excludes 1
Official- diabetes with hypoglycemia without coma (E09.649)
- transitory endocrine and metabolic disorders specific to newborn (P70-P74)Inherited from E00-E89
Code First
OfficialNo Code First sequencing instructions are included in this display for E16.0. Check the code and parent instructions in the Code Book.
Use Additional
Official- code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)
- code for hypoglycemia level, if applicable (E16.A-)
Code Also
OfficialNo Code Also instructions are included in this display for E16.0. Check the code and parent instructions in the Code Book.
Buddy Documentation Tip
Current with CMS: FY2026 ICD-10-CM Apr 1 update (effective Apr 1 – Sep 30, 2026) · CMS-HCC V28, 100% phased in for payment year 2026. FY2027 code set already staged for October 1, 2026. How HCC Buddy stays current →
Is E16.0 an HCC code?
No. E16.0 is a billable ICD-10-CM code with no mapping under the current CMS-HCC V28 community payment model, and none under the ESRD, Part D RxHCC, or HHS-HCC models.
- Code
- E16.0
- Description
- Drug-induced hypoglycemia without coma
- HCC (V28)
- No CMS-HCC V28 mapping
- RAF reference coefficient
- —
- Billable
- Yes
- Payment year
- 2026
Coder workflow notes
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What This Code Means
E16.0 is the ICD-10-CM diagnosis code for drug-induced hypoglycemia without coma. Low blood sugar caused by medication or drugs, but the patient is conscious and alert. E16.0 sits in the ICD-10-CM chapter for endocrine, nutritional and metabolic diseases (e00-e89), within the section covering other disorders of glucose regulation and pancreatic internal secretion (e15-e16).
E16.0 is a billable ICD-10-CM code, but no current CMS-HCC V28 community payment mapping is shown, and none under the ESRD, Part D RxHCC, or HHS-HCC models. Do not assign risk adjustment value from this page when no source-backed mapping is shown; verify the applicable model and payment year.
Always identify and document the specific drug causing the hypoglycemia in the medical record for complete coding.
HCC Buddy maintains structured V28 and V24 mapping, source-labeled coefficient references, and MEAT documentation criteria for E16.0 sourced directly from the CMS-HCC risk adjustment model files and the CMS ICD-10-CM code set.
Coding Tips
Excludes 1, Do NOT code together
- diabetes with hypoglycemia without coma (E09.649)