Question 1

What is ICD-10 code E16.0?

Accepted Answer

E16.0 is the ICD-10-CM diagnosis code for drug-induced hypoglycemia without coma. Low blood sugar caused by medication or drugs, but the patient is conscious and alert. E16.0 sits in the ICD-10-CM chapter for endocrine, nutritional and metabolic diseases (e00-e89), within the section covering other disorders of glucose regulation and pancreatic internal secretion (e15-e16).

E16.0 is a billable ICD-10-CM code but does not map to a payment HCC under the CMS-HCC V28, V24, ESRD, or RxHCC risk adjustment models. It can be reported on Medicare Advantage encounter data submissions but it does not contribute to a beneficiary's RAF score and therefore does not affect risk-adjusted payments to the plan.

Always identify and document the specific drug causing the hypoglycemia in the medical record for complete coding.

Question 2

Is E16.0 an HCC code?

Accepted Answer

No. E16.0 is a billable ICD-10-CM code but does not map to any payment HCC category under the CMS-HCC V28, V24, ESRD, or RxHCC risk adjustment models. It can still be reported on Medicare Advantage encounter data submissions, but it does not contribute to the beneficiary's Risk Adjustment Factor (RAF) score and therefore does not affect the risk-adjusted capitation payment to the plan. V28 reached 100% phase-in for payment year 2026.

Question 3

Is E16.0 billable?

Accepted Answer

Yes. E16.0 is a billable ICD-10-CM code that can be reported on professional and institutional claims as a primary or secondary diagnosis when the provider documentation supports the specific condition described. Billable codes in ICD-10-CM are coded to the highest level of specificity available for the documented diagnosis. E16.0 is current for fiscal year 2026 and remains in the active CMS ICD-10-CM code set published by the National Center for Health Statistics.

Question 4

What is the V28 vs V24 difference for E16.0?

Accepted Answer

E16.0 does not map to a payment HCC under either the CMS-HCC V28 risk adjustment model or the older V24 model. V28 reached 100% phase-in for payment year 2026, replacing V24 which was used during the PY2024–PY2025 transition. Because neither model rewards E16.0 with a risk adjustment factor, it contributes zero to a Medicare Advantage beneficiary's RAF score in either version. Coders should check whether provider documentation supports a more specific child code that does map to a payment HCC.

Question 5

What should coders know when reporting E16.0?

Accepted Answer

Always identify and document the specific drug causing the hypoglycemia in the medical record for complete coding Link this code with the appropriate drug adverse effect code (T36-T50 series) to show the medication relationship

HCC Buddy Code Card

E16.0

Is E16.0 an HCC code?

What This Code Means

Coding Tips

Excludes 1, Do NOT code together

Use Additional Code

Child Codes

Code Hierarchy

Open E16.0 in the Interactive Encoder

E16.0 ICD-10-CM Code: Drug-induced hypoglycemia without coma

HCC Buddy Code Card

E16.0

Is E16.0 an HCC code?

What This Code Means

Coding Tips

Excludes 1, Do NOT code together

Use Additional Code

Child Codes

Code Hierarchy

Open E16.0 in the Interactive Encoder