D82.8

HCC Category Mapping

What This Code Means

An immunodeficiency condition linked to other significant genetic or developmental abnormalities not covered by more specific codes.

Coding Tips

• •Use this code only when the major defect is specified but doesn't fit other D82 categories
• •Document the associated major defect clearly in the medical record for specificity

Clinical Significance

Immunodeficiency associated with other specified major defects encompasses rare syndromic immunodeficiency disorders with defined genetic or developmental abnormalities that do not fit the specific categories of Wiskott-Aldrich, DiGeorge, short-limbed immunodeficiency, or Epstein-Barr virus susceptibility syndromes. Examples include ataxia-telangiectasia, Bloom syndrome, and other DNA repair defect-associated immunodeficiencies.

Documentation Requirements

• ✓Documentation must specify the particular major defect associated with the immunodeficiency, include genetic testing confirming the underlying condition, immunological assessment showing the specific immune deficits, and description of the associated non-immune features.
• ✓Document the relationship between the major defect and the immunodeficiency to support code assignment.

Commonly Confused Codes