D82.0 ICD-10-CM Code: Wiskott-Aldrich syndrome
HCC Buddy Code Card
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FY 2026 Apr update / Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89) / Certain disorders involving the immune mechanism (D80-D89)
D82.0
Billable / SpecificICD-10-CMOfficial ICD-10-CMCodebook guidanceWiskott-Aldrich syndrome
A rare inherited disorder affecting both the immune system and blood cells, causing recurrent infections, bleeding problems, and eczema.
Buddy Insight
Wiskott-Aldrich syndrome is an X-linked recessive primary immunodeficiency characterized by the classic triad of thrombocytopenia with small platelets, eczema, and recurrent infections due to combined T-cell and B-cell dysfunction.
CMS-HCC V28
MappedHCC 115
RAF 0.565
CMS-HCC V24
MappedHCC 47
RAF 0.665
ACA/HHS
MappedHCC 73
Varies by metal level
ESRD/PACE
MappedHCC 47
RAF 0.078
RXHCC
MappedHCC 99
RAF 0.943
Code Book Path
Inclusion Terms
Official- Immunodeficiency with thrombocytopenia and eczema
Excludes 2
OfficialICD-10-CM does not list Excludes 2 notes for D82.0 in this effective period.
Related Child Codes
Includes
OfficialICD-10-CM does not list Includes notes for D82.0 in this effective period.
Excludes 1
Official- ataxia telangiectasia [Louis-Bar] (G11.3)
Code First
OfficialICD-10-CM does not list Code First sequencing instructions for D82.0 in this effective period.
Use Additional
OfficialICD-10-CM does not list Use Additional Code instructions for D82.0 in this effective period.
Code Also
OfficialICD-10-CM does not list Code Also instructions for D82.0 in this effective period.
Buddy Documentation Tip
MEAT Support
Audit Caution
Common Mistakes
Current with CMS: FY2026 ICD-10-CM Apr 1 update (effective Apr 1 – Sep 30, 2026) · CMS-HCC V28, 100% phased in for payment year 2026. FY2027 code set already staged for October 1, 2026. How HCC Buddy stays current →
Is D82.0 an HCC code?
Yes. D82.0 (Wiskott-Aldrich syndrome) maps to Specified Immunodeficiencies and White Blood Cell Disorders under the CMS-HCC V28 risk adjustment model (and Disorders of Immunity under V24), with a community non-dual aged RAF of 0.565. It is billable for payment year 2026.
Coder answer: D82.0 is billable and maps to V28 HCC 115, Specified Immunodeficiencies and White Blood Cell Disorders. Open it in the Code Book for the tabular path, RAF, and MEAT checklist.
- Code
- D82.0
- Description
- Wiskott-Aldrich syndrome
- HCC (V28)
- HCC 115 — Specified Immunodeficiencies and White Blood Cell Disorders
- RAF
- 0.565
- Billable
- Yes
- Payment year
- 2026
HCC Category Mapping
Each model's RAF is its CMS base weight for that model's standard population, so weights are not directly comparable across models: CMS-HCC V28 and V24 use Community, Non-Dual, Aged; ESRD uses the dialysis continuing-enrollee model; RxHCC is the Part D continuing-enrollee, non-low-income, aged weight (a larger scale than CMS-HCC). ACA/HHS has no single weight — it varies by metal level. Actual per-patient RAF contribution depends on member segment, interactions, and the model year used by the payer. V28 is the CMS-HCC model phased in over payment years 2024–2026; V24 remains in use during the transition and for historical data.
Work D82.0 in the Code Book — tabular path, V28 RAF, and MEAT checklist →
MEAT Criteria for D82.0
For D82.0 to count as a valid HCC diagnosis in a given encounter, the provider's documentation must show MEAT: Monitor, Evaluate, Assess, or Treat. A diagnosis from a prior year does not carry forward automatically, it has to be re-documented and supported each calendar year.
- MMonitor: signs, symptoms, disease progression, or lab trending documented in the note
- EEvaluate: test results, medication response, or physical findings reviewed by the provider
- AAssess: explicit mention in the assessment or plan with acknowledgment of status
- TTreat: medication, referral, procedure, therapy, or counseling tied to the diagnosis
Only one of M/E/A/T is required to support the code, but the documentation must be specific enough to show that the provider actually addressed D82.0 during that encounter, not just copy-forwarded from a problem list.
Coder workflow notes
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What This Code Means
D82.0 is the ICD-10-CM diagnosis code for wiskott-aldrich syndrome. A rare inherited disorder affecting both the immune system and blood cells, causing recurrent infections, bleeding problems, and eczema. D82.0 sits in the ICD-10-CM chapter for diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (d50-d89), within the section covering certain disorders involving the immune mechanism (d80-d89).
Under the CMS-HCC V28 risk adjustment model, D82.0 maps to Specified Immunodeficiencies and White Blood Cell Disorders (HCC 115) with a community, non-dual, aged base RAF weight of 0.565. Under the older CMS-HCC V24 model, D82.0 maps to Disorders of Immunity (HCC 47) with a community, non-dual, aged base RAF weight of 0.665. V28 is the CMS-HCC risk adjustment model that reached 100% phase-in for payment year 2026, replacing V24 which was used during the PY2024–PY2025 transition.
This syndrome has multiple manifestations; document immune deficiency, thrombocytopenia, and eczema separately if present. Because D82.0 maps to a payment HCC, the provider's documentation must satisfy MEAT criteria (Monitor, Evaluate, Assess, or Treat) for the encounter to count toward the patient's Medicare Advantage risk adjustment score. When documentation is ambiguous, coders should issue a provider query rather than assume the highest-specificity variant.
HCC Buddy maintains structured V28 and V24 mapping, RAF weights, and MEAT documentation criteria for D82.0 sourced directly from the CMS-HCC risk adjustment model files and the CMS ICD-10-CM code set.
Coding Tips
- •This syndrome has multiple manifestations; document immune deficiency, thrombocytopenia, and eczema separately if present
- •Often requires documentation of specific infections and bleeding episodes for comprehensive clinical picture
Clinical Significance
Wiskott-Aldrich syndrome is an X-linked recessive primary immunodeficiency characterized by the classic triad of thrombocytopenia with small platelets, eczema, and recurrent infections due to combined T-cell and B-cell dysfunction. The condition results from mutations in the WASP gene and carries increased risk of autoimmune disease and lymphoid malignancies, particularly in adolescence and young adulthood.
Documentation Requirements
- ✓Documentation must include the clinical triad components (thrombocytopenia with characteristically small platelet volume, eczema severity, infection history), WASP gene mutation confirmation, complete blood count showing thrombocytopenia with low mean platelet volume, immunoglobulin levels (typically low Immunoglobulin M with elevated Immunoglobulin A and Immunoglobulin E), and treatment plan including consideration of hematopoietic stem cell transplantation.
Commonly Confused Codes
- •D82.1 (DiGeorge syndrome, another immunodeficiency with associated features but different manifestations), D69.3 (immune thrombocytopenic purpura for thrombocytopenia without the immunodeficiency component), D81.89 (other combined immunodeficiencies without the characteristic triad), D80.0 (hereditary hypogammaglobulinemia without the thrombocytopenia and eczema features).