D73.81 ICD-10-CM Code: Neutropenic splenomegaly
HCC Buddy Code Card
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FY 2026 Apr update / Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89) / Other disorders of blood and blood-forming organs (D70-D77)
D73.81
Billable / SpecificICD-10-CMOfficial ICD-10-CMCodebook guidanceNeutropenic splenomegaly
Enlargement of the spleen that occurs in patients with abnormally low white blood cell counts, often related to chemotherapy or bone marrow disorders.
CMS-HCC V28
00
RAF 0
CMS-HCC V24
00
RAF 0
ACA/HHS
00
RAF 0
ESRD/PACE
00
RAF 0
RXHCC
00
RAF 0
Code Trumping
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Code Book Path
Inclusion Terms
Official- Werner-Schultz disease
Excludes 2
OfficialICD-10-CM does not list Excludes 2 notes for D73.81 in this effective period.
Related Child Codes
Includes
OfficialICD-10-CM does not list Includes notes for D73.81 in this effective period.
Excludes 1
OfficialICD-10-CM does not list Excludes 1 notes for D73.81 in this effective period.
Code First
OfficialICD-10-CM does not list Code First sequencing instructions for D73.81 in this effective period.
Use Additional
OfficialICD-10-CM does not list Use Additional Code instructions for D73.81 in this effective period.
Code Also
OfficialICD-10-CM does not list Code Also instructions for D73.81 in this effective period.
Buddy Documentation Tip
Last updated: FY2026 ICD-10-CM Apr update, Apr 1, 2026 through Sep 30, 2026. CMS-HCC V28 is 100% phased in for payment year 2026.
Is D73.81 an HCC code?
No. D73.81 is a billable ICD-10-CM code but does not map to any HCC category in V28, V24, ESRD, or RxHCC.
Coder workflow notes
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This code does not map to an HCC category in any model (V28, V24, ESRD, RxHCC).
What This Code Means
D73.81 is the ICD-10-CM diagnosis code for neutropenic splenomegaly. Enlargement of the spleen that occurs in patients with abnormally low white blood cell counts, often related to chemotherapy or bone marrow disorders. D73.81 sits in the ICD-10-CM chapter for diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (d50-d89), within the section covering other disorders of blood and blood-forming organs (d70-d77).
D73.81 is a billable ICD-10-CM code but does not map to a payment HCC under the CMS-HCC V28, V24, ESRD, or RxHCC risk adjustment models. It can be reported on Medicare Advantage encounter data submissions but it does not contribute to a beneficiary's RAF score and therefore does not affect risk-adjusted payments to the plan.
Document the underlying cause of neutropenia (e.g., chemotherapy, aplastic anemia, or autoimmune condition).
HCC Buddy maintains structured V28 and V24 mapping, RAF weights, and MEAT documentation criteria for D73.81 sourced directly from the CMS-HCC risk adjustment model files and the CMS ICD-10-CM code set.
Coding Tips
- •Document the underlying cause of neutropenia (e.g., chemotherapy, aplastic anemia, or autoimmune condition)
- •Verify the neutropenia diagnosis is also coded separately if it is a distinct condition