D72.820 ICD-10-CM Code: Lymphocytosis (symptomatic)
D72.820 is not a CMS-HCC payment code. MEAT criteria · RAF Calculator · HCC coding software
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FY 2026 Apr update / Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89) / Other disorders of blood and blood-forming organs (D70-D77)
D72.820
Billable / SpecificICD-10-CMOfficial ICD-10-CMCodebook guidanceLymphocytosis (symptomatic)
An abnormally high number of lymphocytes (a type of white blood cell) in the blood that is causing symptoms. Lymphocytes are important for immune function, and elevated levels may indicate infection or immune system activation.
CMS-HCC V28
N/A—
Not mapped
CMS-HCC V24
HistoricalHistorical
Not used for CY2026 payment
ACA/HHS
N/A—
Not mapped
ESRD/PACE
N/A—
Not mapped
RXHCC
N/A—
Not mapped
Code Book Path
Inclusion Terms
Official- Elevated lymphocytes
Excludes 2
Official- autoimmune disease (systemic) NOS (M35.9)Inherited from D50-D89, D72
- certain conditions originating in the perinatal period (P00-P96)Inherited from D50-D89, D72
- complications of pregnancy, childbirth and the puerperium (O00-O9A)Inherited from D50-D89, D72
- congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)Inherited from D50-D89, D72
- endocrine, nutritional and metabolic diseases (E00-E88)Inherited from D50-D89, D72
- human immunodeficiency virus [HIV] disease (B20)Inherited from D50-D89, D72
- injury, poisoning and certain other consequences of external causes (S00-T88)Inherited from D50-D89, D72
- neoplasms (C00-D49)Inherited from D50-D89, D72
- symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)Inherited from D50-D89, D72
- neutropenia (D70)Inherited from D50-D89, D72
Related Codes
Includes
OfficialNo Includes notes are included in this display for D72.820. Check the code and parent instructions in the Code Book.
Excludes 1
Official- basophilia (D72.824)Inherited from D72, D72.8, D72.82
- immunity disorders (D80-D89)Inherited from D72, D72.8, D72.82
- preleukemia (syndrome) (D46.9)Inherited from D72, D72.8, D72.82
- leukemia (C91-C95)Inherited from D72, D72.8, D72.82
- eosinophilia (D72.1)Inherited from D72, D72.8, D72.82
Code First
OfficialNo Code First sequencing instructions are included in this display for D72.820. Check the code and parent instructions in the Code Book.
Use Additional
OfficialNo Use Additional Code instructions are included in this display for D72.820. Check the code and parent instructions in the Code Book.
Code Also
OfficialNo Code Also instructions are included in this display for D72.820. Check the code and parent instructions in the Code Book.
Buddy Documentation Tip
Current with CMS: FY2026 ICD-10-CM Apr 1 update (effective Apr 1 – Sep 30, 2026) · CMS-HCC V28, 100% phased in for payment year 2026. FY2027 code set already staged for October 1, 2026. How HCC Buddy stays current →
Is D72.820 an HCC code?
No. D72.820 is a billable ICD-10-CM code with no mapping under the current CMS-HCC V28 community payment model, and none under the ESRD, Part D RxHCC, or HHS-HCC models.
- Code
- D72.820
- Description
- Lymphocytosis (symptomatic)
- HCC (V28)
- No CMS-HCC V28 mapping
- RAF reference coefficient
- —
- Billable
- Yes
- Payment year
- 2026
Coder workflow notes
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What This Code Means
D72.820 is the ICD-10-CM diagnosis code for lymphocytosis (symptomatic). An abnormally high number of lymphocytes (a type of white blood cell) in the blood that is causing symptoms. Lymphocytes are important for immune function, and elevated levels may indicate infection or immune system activation. D72.820 sits in the ICD-10-CM chapter for diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (d50-d89), within the section covering other disorders of blood and blood-forming organs (d70-d77).
D72.820 is a billable ICD-10-CM code, but no current CMS-HCC V28 community payment mapping is shown, and none under the ESRD, Part D RxHCC, or HHS-HCC models. Do not assign risk adjustment value from this page when no source-backed mapping is shown; verify the applicable model and payment year.
The '(symptomatic)' designation means the patient must have symptoms related to the elevated lymphocytes.
HCC Buddy maintains structured V28 and V24 mapping, source-labeled coefficient references, and MEAT documentation criteria for D72.820 sourced directly from the CMS-HCC risk adjustment model files and the CMS ICD-10-CM code set.
Coding Tips
- •The '(symptomatic)' designation means the patient must have symptoms related to the elevated lymphocytes
- •Document the underlying cause if identified, such as viral infection or leukemia, as this may require additional coding

