D69.49

Billable

Other primary thrombocytopenia

HCC Category Mapping

V28HCC 112 — Von Willebrand Disease and Other Coagulation Defects

0.247

V24HCC 48 — Coagulation Defects and Other Specified Hematological Disorders

0.209

ESRDHCC 48 — Coagulation Defects and Other Specified Hematological Disorders

0.000

What This Code Means

Low platelet counts caused by bone marrow problems or other primary disorders not classified elsewhere.

Coding Tips

•Rule out secondary causes (medications, infections, splenomegaly) before assigning this code
•Document the underlying mechanism if known (decreased production vs. increased destruction)

Clinical Significance

Other primary thrombocytopenia captures primary platelet production or survival disorders not classified as ITP, Evans syndrome, or hereditary thrombocytopenia. This includes conditions such as cyclic thrombocytopenia, amegakaryocytic thrombocytopenia, and other rare primary platelet disorders. It represents a diagnostically challenging category requiring hematology evaluation.

Documentation Requirements

✓Document the specific clinical features and laboratory findings differentiating this from ITP and inherited thrombocytopenias.
✓Record bone marrow biopsy results if performed (showing megakaryocyte number and morphology), serial platelet counts demonstrating the pattern, and exclusion of secondary causes.
✓Note the treatment approach and response.

Commonly Confused Codes

D69.3 (Immune thrombocytopenic purpura) — most common primary thrombocytopenia D69.42 (Congenital/hereditary thrombocytopenia) — when inherited cause is identified D69.6 (Thrombocytopenia, unspecified) — less specific code that should be avoided when a primary etiology is established.

Code Hierarchy

└D69Purpura and other hemorrhagic conditions └D69.4Other primary thrombocytopenia └D69.49Other primary thrombocytopenia

└D69.49Other primary thrombocytopenia