D69.3
BillableImmune thrombocytopenic purpura
HCC Category Mapping
V28HCC 112 — Von Willebrand Disease and Other Coagulation Defects
0.247V24HCC 48 — Coagulation Defects and Other Specified Hematological Disorders
0.209ESRDHCC 48 — Coagulation Defects and Other Specified Hematological Disorders
0.000RxHCCHCC 100 — Immune Thrombocytopenic Purpura
0.000What This Code Means
An autoimmune condition where the body destroys its own platelets, causing low platelet counts and increased bleeding risk.
Coding Tips
- •Document whether this is newly diagnosed or chronic/recurrent
- •Specify if secondary to other conditions (HIV, SLE, medications) or primary ITP
Clinical Significance
Immune thrombocytopenic purpura is an autoimmune condition in which antibodies target platelet surface glycoproteins, causing accelerated platelet destruction and thrombocytopenia. It may be primary (idiopathic) or secondary to infections, autoimmune diseases, or medications. Chronic ITP in adults often requires long-term management with thrombopoietin receptor agonists, rituximab, or splenectomy.
Documentation Requirements
- ✓Document platelet count trends, exclusion of secondary causes (HIV, hepatitis C, SLE, drug-induced), bone marrow biopsy results if performed, and current treatment regimen (corticosteroids, IVIG, TPO receptor agonists, rituximab, splenectomy status).
- ✓Record whether the condition is acute (<12 months) or chronic, and any bleeding complications.
Commonly Confused Codes
D69.41 (Evans syndrome) — ITP combined with autoimmune hemolytic anemiaD69.6 (Thrombocytopenia, unspecified) — less specific and should not be used when ITP is confirmedD69.42 (Congenital/hereditary thrombocytopenia) — inherited rather than autoimmune etiologyD75.822 (Immune-mediated heparin-induced thrombocytopenia) — drug-specific mechanism.
Code Hierarchy
└D69Purpura and other hemorrhagic conditions└D69.3Immune thrombocytopenic purpura
└D69.3Immune thrombocytopenic purpura