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D68.59

Billable

Other primary thrombophilia

HCC Category Mapping

V24HCC 48Coagulation Defects and Other Specified Hematological Disorders
0.209
ESRDHCC 48Coagulation Defects and Other Specified Hematological Disorders
0.000

What This Code Means

Other inherited blood clotting disorders that increase the risk of abnormal blood clot formation not classified elsewhere.

Coding Tips

  • Use this code for thrombophilias not specifically listed (e.g., protein S deficiency, protein C deficiency, dysfibrinogenemia)
  • Document the specific type of thrombophilia identified through testing for complete clinical documentation

Clinical Significance

Other primary thrombophilia captures inherited thrombophilic conditions beyond Factor V Leiden and prothrombin gene mutation, including protein C deficiency, protein S deficiency, antithrombin deficiency, and rare conditions like dysfibrinogenemia with thrombotic tendency. Antithrombin deficiency carries the highest thrombotic risk among inherited thrombophilias with a 25-50 fold increase.

Documentation Requirements

  • Document the specific thrombophilia identified (protein C, protein S, or antithrombin deficiency), laboratory levels and functional assay results, genetic testing if performed, and personal/family history of thrombotic events.
  • Record current anticoagulation therapy and any pregnancy-related considerations, as these conditions significantly impact obstetric management.

Commonly Confused Codes

Code Hierarchy

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