D68.59
BillableOther primary thrombophilia
HCC Category Mapping
V24HCC 48 — Coagulation Defects and Other Specified Hematological Disorders
0.209ESRDHCC 48 — Coagulation Defects and Other Specified Hematological Disorders
0.000What This Code Means
Other inherited blood clotting disorders that increase the risk of abnormal blood clot formation not classified elsewhere.
Coding Tips
- •Use this code for thrombophilias not specifically listed (e.g., protein S deficiency, protein C deficiency, dysfibrinogenemia)
- •Document the specific type of thrombophilia identified through testing for complete clinical documentation
Clinical Significance
Other primary thrombophilia captures inherited thrombophilic conditions beyond Factor V Leiden and prothrombin gene mutation, including protein C deficiency, protein S deficiency, antithrombin deficiency, and rare conditions like dysfibrinogenemia with thrombotic tendency. Antithrombin deficiency carries the highest thrombotic risk among inherited thrombophilias with a 25-50 fold increase.
Documentation Requirements
- ✓Document the specific thrombophilia identified (protein C, protein S, or antithrombin deficiency), laboratory levels and functional assay results, genetic testing if performed, and personal/family history of thrombotic events.
- ✓Record current anticoagulation therapy and any pregnancy-related considerations, as these conditions significantly impact obstetric management.
Commonly Confused Codes
Code Hierarchy
└D68Other coagulation defects└D68.5Primary thrombophilia└D68.59Other primary thrombophilia
└D68.59Other primary thrombophilia