D61.818
BillableOther pancytopenia
HCC Category Mapping
What This Code Means
A reduction in all types of blood cells (red cells, white cells, and platelets) due to causes other than chemotherapy or specified conditions.
Coding Tips
- •Use this code only after excluding chemotherapy-induced and other specified causes
- •Investigate and document the underlying etiology when possible for better clinical clarity
Clinical Significance
Other pancytopenia captures the dangerous reduction of all three blood cell lines from causes other than chemotherapy or other identified drugs, including pancytopenia from viral infections (human immunodeficiency virus, hepatitis, Epstein-Barr virus), nutritional deficiencies (severe folate or vitamin B12 deficiency), hypersplenism, bone marrow infiltration by non-malignant processes, and autoimmune conditions such as systemic lupus erythematosus. Identifying the underlying cause is essential because treatment is directed at the root etiology rather than simply supporting blood counts.
Documentation Requirements
- ✓Document the underlying cause of pancytopenia when identified.
- ✓Record all three cytopenia values: hemoglobin, absolute neutrophil count, and platelet count.
- ✓Include bone marrow biopsy results if performed.
- ✓Document the diagnostic workup performed to identify the cause, including viral serologies, nutritional studies, autoimmune markers, and imaging for splenomegaly or infiltrative processes.
- ✓Record treatment directed at the underlying cause and any supportive measures.