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D59.8

Billable

Other acquired hemolytic anemias

Last updated: FY2026 ICD-10-CM (Oct 1, 2025 – Sep 30, 2026) | CMS-HCC V28 (100% phase-in, PY2026)

Is D59.8 an HCC code?

Yes. D59.8 maps to Hemolytic and Aplastic Anemias under the CMS-HCC V28 risk adjustment model (and Severe Hematological Disorders under V24).

HCC Category Mapping

V28HCC 109Hemolytic and Aplastic Anemias
0.291
V24HCC 46Severe Hematological Disorders
0.666
ESRDHCC 46Severe Hematological Disorders
0.000
RxHCCHCC 96Hemolytic and Aplastic Anemias
0.000

RAF weights shown are the community, non-dual, aged base weights from the CMS risk adjustment model file. Actual per-patient RAF contribution depends on member segment, interactions, and the model year used by the payer. V28 is the CMS-HCC model phased in over payment years 2024–2026; V24 remains in use during the transition and for historical data.

MEAT Criteria for D59.8

For D59.8 to count as a valid HCC diagnosis in a given encounter, the provider's documentation must show MEAT: Monitor, Evaluate, Assess, or Treat. A diagnosis from a prior year does not carry forward automatically — it has to be re-documented and supported each calendar year.

  • MMonitor: signs, symptoms, disease progression, or lab trending documented in the note
  • EEvaluate: test results, medication response, or physical findings reviewed by the provider
  • AAssess: explicit mention in the assessment or plan with acknowledgment of status
  • TTreat: medication, referral, procedure, therapy, or counseling tied to the diagnosis

Only one of M/E/A/T is required to support the code, but the documentation must be specific enough to show that the provider actually addressed D59.8 during that encounter — not just copy-forwarded from a problem list.

What This Code Means

D59.8 is the ICD-10-CM diagnosis code for other acquired hemolytic anemias. Anemia caused by the destruction of red blood cells due to acquired conditions not classified in other hemolytic anemia categories. D59.8 sits in the ICD-10-CM chapter for diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (d50-d89), within the section covering hemolytic anemias (d55-d59).

Under the CMS-HCC V28 risk adjustment model, D59.8 maps to Hemolytic and Aplastic Anemias (HCC 109) with a community, non-dual, aged base RAF weight of 0.291. Under the older CMS-HCC V24 model, D59.8 maps to Severe Hematological Disorders (HCC 46) with a community, non-dual, aged base RAF weight of 0.666. V28 is the CMS-HCC risk adjustment model that reached 100% phase-in for payment year 2026, replacing V24 which was used during the PY2024–PY2025 transition.

This is a catch-all code; document the specific cause of hemolysis to support medical necessity. Because D59.8 maps to a payment HCC, the provider's documentation must satisfy MEAT criteria (Monitor, Evaluate, Assess, or Treat) for the encounter to count toward the patient's Medicare Advantage risk adjustment score. When documentation is ambiguous, coders should issue a provider query rather than assume the highest-specificity variant.

HCC Buddy maintains structured V28 and V24 mapping, RAF weights, and MEAT documentation criteria for D59.8 sourced directly from the CMS-HCC risk adjustment model files and the CMS ICD-10-CM code set.

Coding Tips

  • This is a catch-all code; document the specific cause of hemolysis to support medical necessity
  • Ensure the condition is truly acquired and not congenital or hereditary

Clinical Significance

Other acquired hemolytic anemias is a residual category for acquired conditions causing premature red blood cell destruction that do not fit into the autoimmune, drug-induced, hemolytic-uremic syndrome, or external cause categories. This may include hemolysis associated with infections (malaria-related hemolysis coded elsewhere, but other parasitic or bacterial infections causing hemolysis), mechanical hemolysis from malfunctioning prosthetic devices, or hemolysis associated with liver disease or hypersplenism. The acquired nature distinguishes these from hereditary hemolytic anemias.

Documentation Requirements

  • Document the specific cause or mechanism of acquired hemolysis when identifiable.
  • Record laboratory evidence of hemolysis (low haptoglobin, elevated lactate dehydrogenase, elevated indirect bilirubin, reticulocytosis) and hemoglobin values.
  • Include negative direct antiglobulin test if autoimmune causes have been excluded.
  • Document any underlying conditions contributing to hemolysis and the treatment approach.
  • Clarify that the condition is acquired rather than hereditary.

Commonly Confused Codes

Code Hierarchy

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