D59.19

Billable

Other autoimmune hemolytic anemia

HCC Category Mapping

V28HCC 109 — Hemolytic and Aplastic Anemias

0.291

V24HCC 46 — Severe Hematological Disorders

0.666

ESRDHCC 46 — Severe Hematological Disorders

0.000

RxHCCHCC 96 — Hemolytic and Aplastic Anemias

0.000

What This Code Means

A condition where the immune system attacks and destroys red blood cells, causing anemia. This is a type of autoimmune hemolytic anemia not classified elsewhere.

Coding Tips

•Verify the specific type of autoimmune hemolytic anemia is not better classified under D59.0 (drug-induced) or D59.1 (other specified types)
•Document any associated conditions or triggers that may have caused the immune response

Clinical Significance

Other autoimmune hemolytic anemia encompasses autoimmune-mediated red blood cell destruction that does not fit neatly into the drug-induced, warm, cold, or mixed categories. This may include paroxysmal cold hemoglobinuria (Donath-Landsteiner hemolytic anemia), which involves a biphasic immunoglobulin G antibody that binds red blood cells at cold temperatures and causes complement-mediated lysis upon rewarming. It also captures rare autoimmune hemolytic anemia variants with unusual antibody characteristics or atypical laboratory patterns.

Documentation Requirements

✓Document the specific type of autoimmune hemolytic anemia when known (for example, paroxysmal cold hemoglobinuria).
✓Include direct antiglobulin test results with antibody characterization showing the condition does not fit warm, cold, or mixed categories.
✓Record hemoglobin levels, hemolysis markers, and any specialized testing such as the Donath-Landsteiner test.
✓Document any underlying triggers or associated conditions and the treatment approach.

Commonly Confused Codes

D59.11 (Warm type), D59.12 (Cold type), and D59.13 (Mixed type) are more specific and should be used when those conditions are confirmed.D59.10 (Autoimmune hemolytic anemia, unspecified) is used when the type cannot be determined at all, while D59.19 implies the type is known but does not fit other categories.D59.0 (Drug-induced autoimmune hemolytic anemia) should be used when a causative drug is identified.

Code Hierarchy

└D59Acquired hemolytic anemia └D59.1Other autoimmune hemolytic anemias └D59.19Other autoimmune hemolytic anemia

└D59.19Other autoimmune hemolytic anemia