What is ICD-10 code D58.8?

D58.8 is the ICD-10-CM diagnosis code for Other specified hereditary hemolytic anemias. Other inherited blood disorders that cause red blood cells to break down prematurely, not classified in the more specific categories above. D58.8 is a billable code, meaning it can be reported on a claim as a primary or secondary diagnosis when supported by documentation. D58.8 is part of the FY2026 ICD-10-CM code set published by the CMS National Center for Health Statistics and used on Medicare, Medicaid, and commercial claims in the United States.

Yes. D58.8 is a billable ICD-10-CM code that can be reported on professional and institutional claims as a primary or secondary diagnosis when the provider documentation supports the specific condition described. Billable codes in ICD-10-CM are coded to the highest level of specificity available for the documented diagnosis. D58.8 is current for fiscal year 2026 and remains in the active CMS ICD-10-CM code set published by the National Center for Health Statistics.

Which HCC does D58.8 map to under V28?

D58.8 has no payable CMS-HCC V28 mapping in the final FY2026 CMS file.

What RAF reference is published for D58.8?

D58.8 has no V28 reference coefficient because the final FY2026 source verifies no payable V28 mapping.

What is the V28 vs V24 difference for D58.8?

D58.8 has verified no payable V28 mapping in the final FY2026 source. Select a historical effective period before making any V24 comparison.

What documentation supports D58.8?

Use this code only when the specific hereditary hemolytic anemia type is documented but doesn't fit other D58 codes Include documentation of the specific condition in the medical record D58.8 is not a CMS-HCC V28 payment code in the verified current source, so MEAT is not the payment hook. Documentation still has to support the diagnosis if you report it.

2026 ICD-10-CM D58.8: Other specified hereditary hemolytic

D58.8 is not a CMS-HCC payment code. MEAT criteria · RAF Calculator · HCC Buddy coding tools

ICD-10-CM Code View

HCC Buddy Code Card

Digital ICD-10 code-book layout with official code detail, always-visible risk models, Code Trumping, and Buddy coding guidance.

Code lookupD58.8

Effective periodFY2026 Apr Update (Apr 1-Sep 30)

FY 2026 Apr update / Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89) / Hemolytic anemias (D55-D59)

D58.8

Billable / SpecificICD-10-CMOfficial ICD-10-CMCodebook guidance

Other specified hereditary hemolytic anemias

Other inherited blood disorders that cause red blood cells to break down prematurely, not classified in the more specific categories above.

Buddy Insight

Overview Risk Models Code Book Documentation Audit Notes Edition comparison

CMS-HCC V28

N/A

—

Not risk-adjusted for this model/period.

Not mapped

CMS-HCC V24

Historical

Not used for standard CY2026 Medicare Advantage payment. Select a historical period to review V24.

Not used for CY2026 payment

ACA/HHS

N/A

—

Not risk-adjusted for this model/period.

Not mapped

ESRD/PACE

Mapped

HCC 48

Coagulation Defects and Other...

Code-level coefficient reference

RXHCC

N/A

—

Not risk-adjusted for this model/period.

Not mapped

Code Book Path

Official

D58Other hereditary hemolytic anemias D58.8Other specified hereditary hemolytic anemias

Inclusion Terms

Official

Stomatocytosis

Excludes 2

Official

autoimmune disease (systemic) NOS (M35.9)Inherited from D50-D89
certain conditions originating in the perinatal period (P00-P96)Inherited from D50-D89
complications of pregnancy, childbirth and the puerperium (O00-O9A)Inherited from D50-D89
congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)Inherited from D50-D89
endocrine, nutritional and metabolic diseases (E00-E88)Inherited from D50-D89
human immunodeficiency virus [HIV] disease (B20)Inherited from D50-D89
injury, poisoning and certain other consequences of external causes (S00-T88)Inherited from D50-D89
neoplasms (C00-D49)Inherited from D50-D89
symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)Inherited from D50-D89

Related Codes

Official

D58.0Hereditary spherocytosis D58.1Hereditary elliptocytosis D58.2Other hemoglobinopathies D58.9Hereditary hemolytic anemia, unspecified

Includes

Official

No Includes notes are included in this display for D58.8. Check the code and parent instructions in the Code Book.

Excludes 1

Official

hemolytic anemia of the newborn (P55.-)Inherited from D58

Code First

Official

No Code First sequencing instructions are included in this display for D58.8. Check the code and parent instructions in the Code Book.

Use Additional

Official

No Use Additional Code instructions are included in this display for D58.8. Check the code and parent instructions in the Code Book.

Code Also

Official

No Code Also instructions are included in this display for D58.8. Check the code and parent instructions in the Code Book.

Buddy Documentation Tip

HCC Buddy guidance

Document the specific hereditary hemolytic anemia by name when known.

Include peripheral blood smear findings showing the characteristic red blood cell morphology.

Record hemoglobin levels, reticulocyte count, and hemolysis markers (lactate dehydrogenase, indirect bilirubin, haptoglobin).

Document family history supporting hereditary etiology and any genetic testing results.

MEAT Support

HCC Buddy guidance

Document the specific hereditary hemolytic anemia by name when known.

Include peripheral blood smear findings showing the characteristic red blood cell morphology.

Record hemoglobin levels, reticulocyte count, and hemolysis markers (lactate dehydrogenase, indirect bilirubin, haptoglobin).

Document family history supporting hereditary etiology and any genetic testing results.

Audit Caution

HCC Buddy guidance

Do not use this code when a more specific hereditary hemolytic anemia code exists -

review D55.x through D58.2 first. Ensure the condition is truly hereditary and not acquired (autoimmune, drug-induced, or mechanical). The 'other specified' designation means the specific condition should be identifiable in the documentation even though ICD-10 does not have a unique code for it.

Common Mistakes

HCC Buddy guidance

D58.0 (Hereditary spherocytosis) and D58.1 (Hereditary elliptocytosis) are more specific and should be used when those conditions are documented.

D55.x (Anemia due to enzyme disorders) covers specific enzyme deficiencies like glucose-6-phosphate dehydrogenase deficiency or pyruvate kinase deficiency.

D58.9 (Hereditary hemolytic anemia, unspecified) should only be used when the type cannot be determined at all.

D59.x codes are for acquired, not hereditary, hemolytic anemias.

Current with CMS: FY2026 ICD-10-CM Apr 1 update (effective Apr 1 – Sep 30, 2026) · CMS-HCC V28, 100% phased in for payment year 2026. FY2027 code set already staged for October 1, 2026. How HCC Buddy stays current →

Is D58.8 an HCC code?

D58.8 is not in the CMS-HCC V28 or V24 community payment model. D58.8 has a separate mapping under the CMS-HCC ESRD model (HCC 48 (Coagulation Defects and Other Specified Hematological Disorders)); the applicable result needs member context.

Code: D58.8
Description: Other specified hereditary hemolytic anemias
HCC (V28): No CMS-HCC V28 mapping
RAF reference coefficient: —
Billable: Yes
Payment year: 2026

HCC Category Mapping

ESRDHCC 48, Coagulation Defects and Other Specified Hematological Disorders

Not separately weighted

These are source-labeled model coefficients, not member totals. A category may still be removed by hierarchy or model cleanup rules. Weights are not directly comparable across models: CMS-HCC V28 and V24 use Community, Non-Dual, Aged; ESRD uses the dialysis continuing-enrollee model; RxHCC is the Part D continuing-enrollee, non-low-income, aged weight (a larger scale than CMS-HCC). ACA/HHS has no single weight — it varies by metal level. Actual per-patient RAF contribution depends on member context, hierarchy and cleanup rules, interactions, and the model year used by the payer. V28 is the CMS-HCC model phased in over payment years 2024–2026; V24 remains available for historical review.

Work D58.8 in the Code Book — tabular path, V28 RAF reference, and MEAT checklist →

MEAT review for D58.8

For D58.8, confirm that the documentation supports the diagnosis and meets the applicable coding, encounter, program and payer requirements. MEAT (Monitor, Evaluate, Assess, or Treat) is a review mnemonic, not a universal CMS coding rule.

MMonitor: signs, symptoms, disease progression, or lab trending documented in the note
EEvaluate: test results, medication response, or physical findings reviewed by the provider
AAssess: explicit mention in the assessment or plan with acknowledgment of status
TTreat: medication, referral, procedure, therapy, or counseling tied to the diagnosis

Coder workflow notes

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What This Code Means

D58.8 is the ICD-10-CM diagnosis code for other specified hereditary hemolytic anemias. Other inherited blood disorders that cause red blood cells to break down prematurely, not classified in the more specific categories above. D58.8 sits in the ICD-10-CM chapter for diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (d50-d89), within the section covering hemolytic anemias (d55-d59).

D58.8 has no mapping under the CMS-HCC V28 or V24 community payment models. D58.8 has a separate mapping under the CMS-HCC ESRD model (HCC 48 (Coagulation Defects and Other Specified Hematological Disorders)); the applicable result needs member context. Do not assign V28 risk adjustment value from this page; verify the applicable model and payment year before using this code for risk adjustment.

Use this code only when the specific hereditary hemolytic anemia type is documented but doesn't fit other D58 codes.

HCC Buddy maintains structured V28 and V24 mapping, source-labeled coefficient references, and MEAT documentation criteria for D58.8 sourced directly from the CMS-HCC risk adjustment model files and the CMS ICD-10-CM code set.

Coding Tips

•Use this code only when the specific hereditary hemolytic anemia type is documented but doesn't fit other D58 codes
•Include documentation of the specific condition in the medical record

Clinical Significance

Other specified hereditary hemolytic anemias captures inherited conditions causing premature red blood cell destruction that do not fit into the more specific categories of spherocytosis, elliptocytosis, or hemoglobinopathies. This includes conditions such as stomatocytosis (hereditary hydrocytosis or xerocytosis), acanthocytosis from inherited membrane disorders, and other rare red blood cell enzyme or membrane defects. These conditions share the common feature of shortened red blood cell lifespan with compensatory increased marrow production.

Documentation Requirements

✓Document the specific hereditary hemolytic anemia by name when known.
✓Include peripheral blood smear findings showing the characteristic red blood cell morphology.
✓Record hemoglobin levels, reticulocyte count, and hemolysis markers (lactate dehydrogenase, indirect bilirubin, haptoglobin).
✓Document family history supporting hereditary etiology and any genetic testing results.
✓Note disease severity and current management approach.

Commonly Confused Codes

•D58.0 (Hereditary spherocytosis) and D58.1 (Hereditary elliptocytosis) are more specific and should be used when those conditions are documented.
•D55.x (Anemia due to enzyme disorders) covers specific enzyme deficiencies like glucose-6-phosphate dehydrogenase deficiency or pyruvate kinase deficiency.
•D58.9 (Hereditary hemolytic anemia, unspecified) should only be used when the type cannot be determined at all.
•D59.x codes are for acquired, not hereditary, hemolytic anemias.