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D49.59 ICD-10-CM Code: Neoplasm of unspecified behavior of other genitourinary organ

D49.59 is not a CMS-HCC payment code. MEAT criteria · RAF calculator · HCC Buddy coding tools

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FY 2026 Apr update / Neoplasms (C00-D49) / Neoplasms of unspecified behavior (D49)

D49.59

Billable / SpecificICD-10-CMOfficial ICD-10-CMCodebook guidance

Neoplasm of unspecified behavior of other genitourinary organ

A tumor or growth of unknown behavior found in other parts of the genitourinary system (such as the ureters, urethra, prostate, or other urinary/reproductive organs).

CMS-HCC V28

N/A

Not mapped

CMS-HCC V24

N/A

Not mapped

ACA/HHS

N/A

Not mapped

ESRD/PACE

N/A

Not mapped

RXHCC

N/A

Not mapped

Code Book Path

Official
D49Neoplasms of unspecified behavior
D49.5Neoplasm of unspecified behavior of other genitourinary organs
D49.59Neoplasm of unspecified behavior of other genitourinary organ

Inclusion Terms

Official

ICD-10-CM does not list inclusion terms for D49.59 in this effective period.

Excludes 2

Official

ICD-10-CM does not list Excludes 2 notes for D49.59 in this effective period.

Related Child Codes

Official
D49.51Neoplasm of unspecified behavior of kidney

Includes

Official

ICD-10-CM does not list Includes notes for D49.59 in this effective period.

Excludes 1

Official

ICD-10-CM does not list Excludes 1 notes for D49.59 in this effective period.

Code First

Official

ICD-10-CM does not list Code First sequencing instructions for D49.59 in this effective period.

Use Additional

Official

ICD-10-CM does not list Use Additional Code instructions for D49.59 in this effective period.

Code Also

Official

ICD-10-CM does not list Code Also instructions for D49.59 in this effective period.

Buddy Documentation Tip

HCC Buddy guidance
Specify the exact organ involved (ureter, urethra, prostate, ovary, testis, etc.) when documented for more precise coding
Review pathology and imaging reports to determine if the lesion can be reclassified as benign or malignant

Current with CMS: FY2026 ICD-10-CM Apr 1 update (effective Apr 1 – Sep 30, 2026) · CMS-HCC V28, 100% phased in for payment year 2026. FY2027 code set already staged for October 1, 2026. How HCC Buddy stays current →

Is D49.59 an HCC code?

No. D49.59 is a billable ICD-10-CM code but does not map to any HCC category in V28, V24, ESRD, or RxHCC.

Code
D49.59
Description
Neoplasm of unspecified behavior of other genitourinary organ
HCC (V28)
No CMS-HCC V28 mapping
RAF
Billable
Yes
Payment year
2026

Coder workflow notes

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This code does not map to an HCC category in any model (V28, V24, ESRD, RxHCC).

What This Code Means

D49.59 is the ICD-10-CM diagnosis code for neoplasm of unspecified behavior of other genitourinary organ. A tumor or growth of unknown behavior found in other parts of the genitourinary system (such as the ureters, urethra, prostate, or other urinary/reproductive organs). D49.59 sits in the ICD-10-CM chapter for neoplasms (c00-d49), within the section covering neoplasms of unspecified behavior (d49).

D49.59 is a billable ICD-10-CM code but does not map to a payment HCC under the CMS-HCC V28, V24, ESRD, or RxHCC risk adjustment models. It can be reported on Medicare Advantage encounter data submissions but it does not contribute to a beneficiary's RAF score and therefore does not affect risk-adjusted payments to the plan.

Specify the exact organ involved (ureter, urethra, prostate, ovary, testis, etc.) when documented for more precise coding.

HCC Buddy maintains structured V28 and V24 mapping, RAF weights, and MEAT documentation criteria for D49.59 sourced directly from the CMS-HCC risk adjustment model files and the CMS ICD-10-CM code set.

Coding Tips

  • Specify the exact organ involved (ureter, urethra, prostate, ovary, testis, etc.) when documented for more precise coding
  • Review pathology and imaging reports to determine if the lesion can be reclassified as benign or malignant

Child Codes

Code Hierarchy

D49.59 code history

Code setChange
FY2017 (effective Oct 1, 2016)Added to the code set

Source: official CMS ICD-10-CM order and addenda files, FY2016 through FY2027.

Work D49.59 in HCC Buddy

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