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D37.3 ICD-10-CM Code: Neoplasm of uncertain behavior of appendix

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FY 2026 Apr update / Neoplasms (C00-D49) / Neoplasms of uncertain behavior, polycythemia vera and myelodysplastic syndromes (D37-D48)

D37.3

Billable / SpecificICD-10-CMOfficial ICD-10-CMCodebook guidance

Neoplasm of uncertain behavior of appendix

This code describes an abnormal growth in the appendix that cannot yet be determined to be either cancer or a benign (non-cancerous) tumor. It represents a condition requiring further investigation or monitoring to establish its true nature.

CMS-HCC V28

0

0

RAF 0

CMS-HCC V24

0

0

RAF 0

ACA/HHS

0

0

RAF 0

ESRD/PACE

0

0

RAF 0

RXHCC

0

0

RAF 0

Code Trumping

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Code Book Path

Official
D37Neoplasm of uncertain behavior of oral cavity and digestive organs
D37.3Neoplasm of uncertain behavior of appendix

Inclusion Terms

Official

ICD-10-CM does not list inclusion terms for D37.3 in this effective period.

Excludes 2

Official

ICD-10-CM does not list Excludes 2 notes for D37.3 in this effective period.

Related Child Codes

Official
D37.0Neoplasm of uncertain behavior of lip, oral cavity and pharynx
D37.1Neoplasm of uncertain behavior of stomach
D37.2Neoplasm of uncertain behavior of small intestine
D37.4Neoplasm of uncertain behavior of colon
D37.5Neoplasm of uncertain behavior of rectum

Includes

Official

ICD-10-CM does not list Includes notes for D37.3 in this effective period.

Excludes 1

Official
  • stromal tumors of uncertain behavior of digestive system (D48.1-)

Code First

Official

ICD-10-CM does not list Code First sequencing instructions for D37.3 in this effective period.

Use Additional

Official

ICD-10-CM does not list Use Additional Code instructions for D37.3 in this effective period.

Code Also

Official

ICD-10-CM does not list Code Also instructions for D37.3 in this effective period.

Buddy Documentation Tip

HCC Buddy guidance
Use this code when pathology reports indicate uncertain or indeterminate behavior of appendiceal lesions, not when the tumor is definitively benign (D12.3) or malignant (C18.1)
Ensure documentation supports the uncertain nature of the neoplasm; if subsequent testing clarifies the diagnosis, update coding to the appropriate benign or malignant code

Last updated: FY2026 ICD-10-CM Apr update, Apr 1, 2026 through Sep 30, 2026. CMS-HCC V28 is 100% phased in for payment year 2026.

Is D37.3 an HCC code?

No. D37.3 is a billable ICD-10-CM code but does not map to any HCC category in V28, V24, ESRD, or RxHCC.

This code does not map to an HCC category in any model (V28, V24, ESRD, RxHCC).

What This Code Means

D37.3 is the ICD-10-CM diagnosis code for neoplasm of uncertain behavior of appendix. This code describes an abnormal growth in the appendix that cannot yet be determined to be either cancer or a benign (non-cancerous) tumor. It represents a condition requiring further investigation or monitoring to establish its true nature. D37.3 sits in the ICD-10-CM chapter for neoplasms (c00-d49), within the section covering neoplasms of uncertain behavior, polycythemia vera and myelodysplastic syndromes (d37-d48).

D37.3 is a billable ICD-10-CM code but does not map to a payment HCC under the CMS-HCC V28, V24, ESRD, or RxHCC risk adjustment models. It can be reported on Medicare Advantage encounter data submissions but it does not contribute to a beneficiary's RAF score and therefore does not affect risk-adjusted payments to the plan.

Use this code when pathology reports indicate uncertain or indeterminate behavior of appendiceal lesions, not when the tumor is definitively benign (D12.3) or malignant (C18.1).

HCC Buddy maintains structured V28 and V24 mapping, RAF weights, and MEAT documentation criteria for D37.3 sourced directly from the CMS-HCC risk adjustment model files and the CMS ICD-10-CM code set.

Coding Tips

  • Use this code when pathology reports indicate uncertain or indeterminate behavior of appendiceal lesions, not when the tumor is definitively benign (D12.3) or malignant (C18.1)
  • Ensure documentation supports the uncertain nature of the neoplasm; if subsequent testing clarifies the diagnosis, update coding to the appropriate benign or malignant code

Child Codes

Code Hierarchy

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