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D33.2 ICD-10-CM Code: Benign neoplasm of brain, unspecified

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FY 2026 Apr update / Neoplasms (C00-D49) / Benign neoplasms, except benign neuroendocrine tumors (D10-D36)

D33.2

Billable / SpecificICD-10-CMOfficial ICD-10-CMCodebook guidance

Benign neoplasm of brain, unspecified

A non-cancerous brain tumor when the specific location within the brain has not been determined or documented.

Buddy the Bee presenting code insight

Buddy Insight

Benign neoplasm of the brain, unspecified, is used when a benign brain tumor is documented but the specific location (supratentorial vs.

CMS-HCC V28

HCC 23

RAF 0.251

CMS-HCC V24

HCC 12

RAF 0.150

ACA/HHS

0

0

RAF 0

ESRD/PACE

HCC 12

RAF 0.0

RXHCC

HCC 22

RAF 0.0

Code Trumping

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Code Book Path

Official
D33Benign neoplasm of brain and other parts of central nervous system
D33.2Benign neoplasm of brain, unspecified

Inclusion Terms

Official

ICD-10-CM does not list inclusion terms for D33.2 in this effective period.

Excludes 2

Official

ICD-10-CM does not list Excludes 2 notes for D33.2 in this effective period.

Related Child Codes

Official
D33.0Benign neoplasm of brain, supratentorial
D33.1Benign neoplasm of brain, infratentorial
D33.3Benign neoplasm of cranial nerves
D33.4Benign neoplasm of spinal cord
D33.7Benign neoplasm of other specified parts of central nervous system

Includes

Official

ICD-10-CM does not list Includes notes for D33.2 in this effective period.

Excludes 1

Official
  • angioma (D18.0-)
  • benign neoplasm of meninges (D32.-)
  • benign neoplasm of peripheral nerves and autonomic nervous system (D36.1-)
  • hemangioma (D18.0-)
  • neurofibromatosis (Q85.0-)

Code First

Official

ICD-10-CM does not list Code First sequencing instructions for D33.2 in this effective period.

Use Additional

Official

ICD-10-CM does not list Use Additional Code instructions for D33.2 in this effective period.

Code Also

Official

ICD-10-CM does not list Code Also instructions for D33.2 in this effective period.

Buddy Documentation Tip

HCC Buddy guidance
At minimum, documentation of a benign brain tumor from imaging or pathology is required.
Every effort should be made to determine whether the tumor is supratentorial (D33.0) or infratentorial (D33.1) by reviewing MRI reports.
Query the provider or radiologist if the location is not specified.
Document the clinical impact and management plan.

MEAT Support

HCC Buddy guidance
At minimum, documentation of a benign brain tumor from imaging or pathology is required.
Every effort should be made to determine whether the tumor is supratentorial (D33.0) or infratentorial (D33.1) by reviewing MRI reports.
Query the provider or radiologist if the location is not specified.
Document the clinical impact and management plan.

Audit Caution

HCC Buddy guidance
MRI reports almost always specify the tumor location, so this unspecified code should rarely be necessary. Review all available imaging before assigning D33.
Do not use this code for meningeal tumors (D32 series) or cranial nerve tumors (D33.3). Payers may request additional documentation when this unspecified code is submitted.

Common Mistakes

HCC Buddy guidance
D33.0 (supratentorial) and D33.1 (infratentorial) are preferred when location is specified
D33.9 (benign CNS neoplasm, unspecified) is even less specific and covers the entire CNS
D43.2 (brain, uncertain behavior) is for tumors where benign vs. malignant is unclear.

Last updated: FY2026 ICD-10-CM Apr update, Apr 1, 2026 through Sep 30, 2026. CMS-HCC V28 is 100% phased in for payment year 2026.

Is D33.2 an HCC code?

Yes. D33.2 maps to Melanoma and Other Skin Cancers under the CMS-HCC V28 risk adjustment model (and Breast, Prostate, and Other Cancers and Tumors under V24).

HCC Category Mapping

V28HCC 23, Melanoma and Other Skin Cancers
0.251
V24HCC 12, Breast, Prostate, and Other Cancers and Tumors
0.150
ESRDHCC 12, Breast, Prostate, and Other Cancers and Tumors
0.000
RxHCCHCC 22, Cancer, Other Specified Sites
0.000

RAF weights shown are the community, non-dual, aged base weights from the CMS risk adjustment model file. Actual per-patient RAF contribution depends on member segment, interactions, and the model year used by the payer. V28 is the CMS-HCC model phased in over payment years 2024–2026; V24 remains in use during the transition and for historical data.

MEAT Criteria for D33.2

For D33.2to count as a valid HCC diagnosis in a given encounter, the provider's documentation must show MEAT: Monitor, Evaluate, Assess, or Treat. A diagnosis from a prior year does not carry forward automatically, it has to be re-documented and supported each calendar year.

  • MMonitor: signs, symptoms, disease progression, or lab trending documented in the note
  • EEvaluate: test results, medication response, or physical findings reviewed by the provider
  • AAssess: explicit mention in the assessment or plan with acknowledgment of status
  • TTreat: medication, referral, procedure, therapy, or counseling tied to the diagnosis

Only one of M/E/A/T is required to support the code, but the documentation must be specific enough to show that the provider actually addressed D33.2 during that encounter, not just copy-forwarded from a problem list.

What This Code Means

D33.2 is the ICD-10-CM diagnosis code for benign neoplasm of brain, unspecified. A non-cancerous brain tumor when the specific location within the brain has not been determined or documented. D33.2 sits in the ICD-10-CM chapter for neoplasms (c00-d49), within the section covering benign neoplasms, except benign neuroendocrine tumors (d10-d36).

Under the CMS-HCC V28 risk adjustment model, D33.2 maps to Melanoma and Other Skin Cancers (HCC 23) with a community, non-dual, aged base RAF weight of 0.251. Under the older CMS-HCC V24 model, D33.2 maps to Breast, Prostate, and Other Cancers and Tumors (HCC 12) with a community, non-dual, aged base RAF weight of 0.150. V28 is the CMS-HCC risk adjustment model that reached 100% phase-in for payment year 2026, replacing V24 which was used during the PY2024–PY2025 transition.

This is an unspecified code; attempt to obtain clarification on whether the tumor is supratentorial or infratentorial. Because D33.2 maps to a payment HCC, the provider's documentation must satisfy MEAT criteria (Monitor, Evaluate, Assess, or Treat) for the encounter to count toward the patient's Medicare Advantage risk adjustment score. When documentation is ambiguous, coders should issue a provider query rather than assume the highest-specificity variant.

HCC Buddy maintains structured V28 and V24 mapping, RAF weights, and MEAT documentation criteria for D33.2 sourced directly from the CMS-HCC risk adjustment model files and the CMS ICD-10-CM code set.

Coding Tips

  • This is an unspecified code; attempt to obtain clarification on whether the tumor is supratentorial or infratentorial
  • Use only when the provider documentation does not specify the anatomical location within the brain

Clinical Significance

Benign neoplasm of the brain, unspecified, is used when a benign brain tumor is documented but the specific location (supratentorial vs. infratentorial) is not specified in the medical record. This code represents an incomplete documentation scenario, as modern neuroimaging typically localizes brain tumors precisely. It may be appropriate during initial evaluation before definitive imaging is obtained.

Documentation Requirements

  • At minimum, documentation of a benign brain tumor from imaging or pathology is required.
  • Every effort should be made to determine whether the tumor is supratentorial (D33.0) or infratentorial (D33.1) by reviewing MRI reports.
  • Query the provider or radiologist if the location is not specified.
  • Document the clinical impact and management plan.

Commonly Confused Codes

  • D33.0 (supratentorial) and D33.1 (infratentorial) are preferred when location is specified
  • D33.9 (benign CNS neoplasm, unspecified) is even less specific and covers the entire CNS
  • D43.2 (brain, uncertain behavior) is for tumors where benign vs. malignant is unclear.

Child Codes

Code Hierarchy

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