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C95.92

Billable

Leukemia, unspecified, in relapse

HCC Category Mapping

V28HCC 22Colorectal, Bladder, and Other Cancers
0.000
V24HCC 10Lymphoma and Other Cancers
0.675
ESRDHCC 10Lymphoma and Other Cancers
0.000
RxHCCHCC 19Lymphoma and Other Cancers
0.000

What This Code Means

A type of blood cancer (leukemia) of unknown cell type that has returned or worsened after a period of remission.

Coding Tips

  • Relapse indicates the cancer has recurred after achieving remission; ensure documentation supports this status
  • Do not confuse relapse with initial presentation or failure to achieve remission

Clinical Significance

Leukemia, unspecified, in relapse indicates recurrence of a leukemia whose type was never determined, following a period of remission. This scenario presents an urgent need for comprehensive diagnostic evaluation at the time of relapse to guide appropriate salvage therapy.

Documentation Requirements

  • Documentation must confirm prior remission followed by disease recurrence.
  • At relapse, comprehensive diagnostic workup (flow cytometry, cytogenetics, molecular studies) should be performed and documented to finally characterize the leukemia type.
  • Current disease status and treatment approach should be recorded.

Commonly Confused Codes

Code Hierarchy

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