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C95.11 ICD-10-CM Code: Chronic leukemia of unspecified cell type, in remission

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FY 2026 Apr update / Neoplasms (C00-D49) / Malignant neoplasms of lymphoid, hematopoietic and related tissue (C81-C96)

C95.11

Billable / SpecificICD-10-CMOfficial ICD-10-CMCodebook guidance

Chronic leukemia of unspecified cell type, in remission

A chronic leukemia of unknown cell type where the cancer has responded to treatment and is in remission.

Buddy the Bee presenting code insight

Buddy Insight

Chronic leukemia of unspecified cell type in remission indicates a chronic leukemia of undetermined lineage that has responded to treatment.

CMS-HCC V28

HCC 22

RAF 0.0

CMS-HCC V24

HCC 10

RAF 0.675

ACA/HHS

0

0

RAF 0

ESRD/PACE

HCC 10

RAF 0.0

RXHCC

HCC 19

RAF 0.0

Code Trumping

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Code Book Path

Official
C95Leukemia of unspecified cell type
C95.1Chronic leukemia of unspecified cell type
C95.11Chronic leukemia of unspecified cell type, in remission

Inclusion Terms

Official

ICD-10-CM does not list inclusion terms for C95.11 in this effective period.

Excludes 2

Official

ICD-10-CM does not list Excludes 2 notes for C95.11 in this effective period.

Related Child Codes

Official
C95.10Chronic leukemia of unspecified cell type not having achieved remission
C95.12Chronic leukemia of unspecified cell type, in relapse

Includes

Official

ICD-10-CM does not list Includes notes for C95.11 in this effective period.

Excludes 1

Official

ICD-10-CM does not list Excludes 1 notes for C95.11 in this effective period.

Code First

Official

ICD-10-CM does not list Code First sequencing instructions for C95.11 in this effective period.

Use Additional

Official

ICD-10-CM does not list Use Additional Code instructions for C95.11 in this effective period.

Code Also

Official

ICD-10-CM does not list Code Also instructions for C95.11 in this effective period.

Buddy Documentation Tip

HCC Buddy guidance
Documentation must confirm remission status with appropriate clinical evidence such as normalization of blood counts, resolution of lymphadenopathy or splenomegaly, and molecular or cytogenetic response if applicable.
The reason for unspecified cell type and attempts to classify should be noted.

MEAT Support

HCC Buddy guidance
Documentation must confirm remission status with appropriate clinical evidence such as normalization of blood counts, resolution of lymphadenopathy or splenomegaly, and molecular or cytogenetic response if applicable.
The reason for unspecified cell type and attempts to classify should be noted.

Audit Caution

HCC Buddy guidance
Remission criteria for chronic leukemias differ by subtype, making unspecified status particularly problematic for determining adequate treatment response.
Query the provider for the cell lineage to enable appropriate remission assessment.
Do not code remission without explicit provider documentation.

Common Mistakes

HCC Buddy guidance
C91.11 (chronic lymphocytic leukemia, in remission), C92.11 (chronic myeloid leukemia, in remission), and C93.11 (chronic myelomonocytic leukemia, in remission) are more specific alternatives.
C95.10 and C95.12 differ by treatment response status.
Z85.6 is premature during active surveillance.

Last updated: FY2026 ICD-10-CM Apr update, Apr 1, 2026 through Sep 30, 2026. CMS-HCC V28 is 100% phased in for payment year 2026.

Is C95.11 an HCC code?

Yes. C95.11 maps to Colorectal, Bladder, and Other Cancers under the CMS-HCC V28 risk adjustment model (and Lymphoma and Other Cancers under V24).

HCC Category Mapping

V28HCC 22, Colorectal, Bladder, and Other Cancers
0.000
V24HCC 10, Lymphoma and Other Cancers
0.675
ESRDHCC 10, Lymphoma and Other Cancers
0.000
RxHCCHCC 19, Lymphoma and Other Cancers
0.000

RAF weights shown are the community, non-dual, aged base weights from the CMS risk adjustment model file. Actual per-patient RAF contribution depends on member segment, interactions, and the model year used by the payer. V28 is the CMS-HCC model phased in over payment years 2024–2026; V24 remains in use during the transition and for historical data.

MEAT Criteria for C95.11

For C95.11to count as a valid HCC diagnosis in a given encounter, the provider's documentation must show MEAT: Monitor, Evaluate, Assess, or Treat. A diagnosis from a prior year does not carry forward automatically, it has to be re-documented and supported each calendar year.

  • MMonitor: signs, symptoms, disease progression, or lab trending documented in the note
  • EEvaluate: test results, medication response, or physical findings reviewed by the provider
  • AAssess: explicit mention in the assessment or plan with acknowledgment of status
  • TTreat: medication, referral, procedure, therapy, or counseling tied to the diagnosis

Only one of M/E/A/T is required to support the code, but the documentation must be specific enough to show that the provider actually addressed C95.11 during that encounter, not just copy-forwarded from a problem list.

What This Code Means

C95.11 is the ICD-10-CM diagnosis code for chronic leukemia of unspecified cell type, in remission. A chronic leukemia of unknown cell type where the cancer has responded to treatment and is in remission. C95.11 sits in the ICD-10-CM chapter for neoplasms (c00-d49), within the section covering malignant neoplasms of lymphoid, hematopoietic and related tissue (c81-c96).

Under the CMS-HCC V28 risk adjustment model, C95.11 maps to Colorectal, Bladder, and Other Cancers (HCC 22) with a community, non-dual, aged base RAF weight of 0.000. Under the older CMS-HCC V24 model, C95.11 maps to Lymphoma and Other Cancers (HCC 10) with a community, non-dual, aged base RAF weight of 0.675. V28 is the CMS-HCC risk adjustment model that reached 100% phase-in for payment year 2026, replacing V24 which was used during the PY2024–PY2025 transition.

Confirm remission status is documented; chronic leukemias may have longer remission periods than acute types. Because C95.11 maps to a payment HCC, the provider's documentation must satisfy MEAT criteria (Monitor, Evaluate, Assess, or Treat) for the encounter to count toward the patient's Medicare Advantage risk adjustment score. When documentation is ambiguous, coders should issue a provider query rather than assume the highest-specificity variant.

HCC Buddy maintains structured V28 and V24 mapping, RAF weights, and MEAT documentation criteria for C95.11 sourced directly from the CMS-HCC risk adjustment model files and the CMS ICD-10-CM code set.

Coding Tips

  • Confirm remission status is documented; chronic leukemias may have longer remission periods than acute types
  • If the specific cell type is identified, update to the appropriate chronic leukemia code

Clinical Significance

Chronic leukemia of unspecified cell type in remission indicates a chronic leukemia of undetermined lineage that has responded to treatment. True remission in chronic leukemias may be more difficult to define than in acute forms, and the criteria should be specified in documentation.

Documentation Requirements

  • Documentation must confirm remission status with appropriate clinical evidence such as normalization of blood counts, resolution of lymphadenopathy or splenomegaly, and molecular or cytogenetic response if applicable.
  • The reason for unspecified cell type and attempts to classify should be noted.

Commonly Confused Codes

  • C91.11 (chronic lymphocytic leukemia, in remission), C92.11 (chronic myeloid leukemia, in remission), and C93.11 (chronic myelomonocytic leukemia, in remission) are more specific alternatives.
  • C95.10 and C95.12 differ by treatment response status.
  • Z85.6 is premature during active surveillance.

Child Codes

Code Hierarchy

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