C94.00

Billable

Acute erythroid leukemia, not having achieved remission

HCC Category Mapping

V28HCC 17 — Metastatic Cancer and Acute Leukemia

0.368

V24HCC 8 — Metastatic Cancer and Acute Leukemia

2.484

ESRDHCC 8 — Metastatic Cancer and Acute Leukemia

0.000

RxHCCHCC 19 — Lymphoma and Other Cancers

0.000

What This Code Means

A rare type of blood cancer where cancer cells develop from red blood cell precursors and have not responded to treatment.

Coding Tips

•Acute erythroid leukemia is a rare subtype; ensure pathology confirms this diagnosis before coding
•The fifth character '0' indicates no remission; document treatment response status

Clinical Significance

Acute erythroid leukemia not having achieved remission is an extremely rare subtype of acute myeloid leukemia where the neoplastic cells arise from erythroid (red blood cell) precursors. Under the current WHO classification, pure erythroid leukemia requires at least 80% erythroid precursors in the bone marrow, making precise pathologic diagnosis essential.

Documentation Requirements

✓Bone marrow biopsy with morphology and immunophenotyping must confirm erythroid lineage predominance.
✓Documentation should include blast percentage, erythroid precursor percentage, treatment history, and current disease status confirming remission has not been achieved.
✓Cytogenetic findings should be noted given frequent complex karyotypes.

Commonly Confused Codes

D46.20 (refractory anemia with excess of blasts, unspecified) may present with erythroid hyperplasia but is a myelodysplastic syndrome.C92.00 (acute myeloblastic leukemia) is the standard myeloid leukemia without erythroid predominance.C94.01 and C94.02 are the same disease in remission or relapse.

Code Hierarchy

└C94Other leukemias of specified cell type └C94.0Acute erythroid leukemia └C94.00Acute erythroid leukemia, not having achieved remission

└C94.00Acute erythroid leukemia, not having achieved remission