C92.30

HCC Category Mapping

What This Code Means

A solid tumor made of myeloid cancer cells (usually found outside the bone marrow) that has not responded to treatment.

Coding Tips

• •Myeloid sarcoma is also called granulocytic sarcoma or chloroma; document the site of the tumor
• •Confirm that remission has not been achieved in the documentation

Clinical Significance

Myeloid sarcoma (also known as granulocytic sarcoma or chloroma) is a rare extramedullary tumor composed of immature myeloid cells, typically associated with or preceding acute myeloid leukemia. It can occur in virtually any anatomic site including skin, bone, lymph nodes, gastrointestinal tract, and central nervous system. The 'not in remission' status indicates active tumor burden requiring systemic treatment, as local therapy alone is generally insufficient.

Documentation Requirements

• ✓Documentation must identify the specific anatomic site(s) of the myeloid sarcoma and confirm the myeloid lineage by immunohistochemistry (MPO, CD68, CD117, lysozyme).
• ✓Association with concurrent or prior AML should be documented.
• ✓Biopsy confirmation is essential as myeloid sarcoma can mimic other malignancies.
• ✓Staging workup including bone marrow biopsy and imaging to assess for concurrent AML must be recorded.

Commonly Confused Codes