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FY2027 ICD-10-CM reference

C92.01: Acute myeloblastic leukemia, in remission

By the HCC Buddy Coding Team

The official ICD-10-CM descriptor is Acute myeloblastic leukemia, in remission. The FY2027 annual edition starts October 1, 2026. Check the edition that applies to the encounter or inpatient discharge, including any April update.

Billable code. Verified against the official FY2027 order file.

CMS-HCC V28

  • HCC 17: Cancer Metastatic to Lung, Liver, Brain, and Other Organs; Acute Myeloid Leukemia Except Promyelocytic · RAF 4.209, Community Non-Dual Aged (CNA)

Payment year 2027, 2026 dates of service. HCC from the CMS 2027 Initial ICD-10-CM Mappings; RAF from the CMS-HCC V28 relative factors. For 2027 dates of service, CMS has not yet published the payment year 2028 mappings.

CMS-HCC V24

Not used for payment year 2027 Medicare Advantage payment

ESRD

  • HCC 8: Metastatic Cancer and Acute Leukemia

Coefficient pending: payment year 2027 coefficients for this model are not yet verified, so no RAF is shown. Mapping: PY2026 CMS mapping; CMS 2027 initial file unchanged.

PACE

Source verification pending

RxHCC

  • HCC 19: Leukemias and Other Hematologic Cancers

Coefficient pending: payment year 2027 coefficients for this model are not yet verified, so no RAF is shown. Mapping: PY2026 CMS mapping; CMS 2027 initial file unchanged.

HHS-HCC

  • HCC 8: Metastatic Cancer

RAF not applicable: HHS-HCC weights vary by metal level. Mapping: HHS-HCC 2026 benefit year.

FY2027 Tabular instructions

Instructions below include applicable chapter, section and parent-code notes. Each note identifies where it appears in the official source.

Instructional note

Functional activity

Source: C00-D49 (chapter, inherited).

Instructional note

All neoplasms are classified in this chapter, whether they are functionally active or not. An additional code from Chapter 4 may be used, to identify functional activity associated with any neoplasm.

Source: C00-D49 (chapter, inherited).

Instructional note

Morphology [Histology]

Source: C00-D49 (chapter, inherited).

Instructional note

Chapter 2 classifies neoplasms primarily by site (topography), with broad groupings for behavior, malignant, in situ, benign, etc. The Table of Neoplasms should be used to identify the correct topography code. In a few cases, such as for malignant melanoma and certain neuroendocrine tumors, the morphology (histologic type) is included in the category and codes.

Source: C00-D49 (chapter, inherited).

Instructional note

Primary malignant neoplasms overlapping site boundaries

Source: C00-D49 (chapter, inherited).

Instructional note

A primary malignant neoplasm that overlaps two or more contiguous (next to each other) sites should be classified to the subcategory/code .8 ('overlapping lesion'), unless the combination is specifically indexed elsewhere. For multiple neoplasms of the same site that are not contiguous, such as tumors in different quadrants of the same breast, codes for each site should be assigned.

Source: C00-D49 (chapter, inherited).

Instructional note

Malignant neoplasm of ectopic tissue

Source: C00-D49 (chapter, inherited).

Instructional note

Malignant neoplasms of ectopic tissue are to be coded to the site mentioned, e.g., ectopic pancreatic malignant neoplasms are coded to pancreas, unspecified (C25.9).

Source: C00-D49 (chapter, inherited).

Excludes2

Kaposi's sarcoma of lymph nodes (C46.3)

Source: C81-C96 (section, inherited).

Excludes2

secondary and unspecified neoplasm of lymph nodes (C77.-)

Source: C81-C96 (section, inherited).

Excludes2

secondary neoplasm of bone marrow (C79.52)

Source: C81-C96 (section, inherited).

Excludes2

secondary neoplasm of spleen (C78.89)

Source: C81-C96 (section, inherited).

Includes

granulocytic leukemia

Source: C92 (category, inherited).

Includes

myelogenous leukemia

Source: C92 (category, inherited).

Code also

, if applicable, pancytopenia (acquired) (D61.818)

Source: C92 (category, inherited).

Excludes1

personal history of leukemia (Z85.6)

Source: C92 (category, inherited).

Instructional note

Acute myeloblastic leukemia, minimal differentiation

Source: C92.0 (self, inherited).

Instructional note

Acute myeloblastic leukemia (with maturation)

Source: C92.0 (self, inherited).

Instructional note

Acute myeloblastic leukemia 1/ETO

Source: C92.0 (self, inherited).

Instructional note

Acute myeloblastic leukemia M0

Source: C92.0 (self, inherited).

Instructional note

Acute myeloblastic leukemia M1

Source: C92.0 (self, inherited).

Instructional note

Acute myeloblastic leukemia M2

Source: C92.0 (self, inherited).

Instructional note

Acute myeloblastic leukemia with t(8;21)

Source: C92.0 (self, inherited).

Instructional note

Acute myeloblastic leukemia (without a FAB classification) NOS

Source: C92.0 (self, inherited).

Instructional note

Refractory anemia with excess blasts in transformation [RAEB T]

Source: C92.0 (self, inherited).

Excludes1

acute exacerbation of chronic myeloid leukemia (C92.10)

Source: C92.0 (self, inherited).

Excludes1

refractory anemia with excess of blasts not in transformation (D46.2-)

Source: C92.0 (self, inherited).

Source: CMS FY2027 Tabular List and Alphabetic Index.

Open Tabular instructions and code details

Compare the FY2027 additions, removals and billable-status changes

What does C92.01 mean in FY2027?

The official ICD-10-CM descriptor is Acute myeloblastic leukemia, in remission. The FY2027 annual edition starts October 1, 2026. Check the edition that applies to the encounter or inpatient discharge, including any April update.

Is C92.01 billable in FY2027?

The FY2027 order file marks C92.01 as billable. Check the complete Tabular instructions and documentation before assigning it.

Does C92.01 map to an HCC?

In the CMS 2027 Initial ICD-10-CM Mappings (payment year 2027, 2026 dates of service), C92.01 maps to CMS-HCC V28 HCC 17 (Cancer Metastatic to Lung, Liver, Brain, and Other Organs; Acute Myeloid Leukemia Except Promyelocytic). For 2027 dates of service, CMS has not yet published the payment year 2028 mappings. Under the PY2026 CMS mapping; CMS 2027 initial file unchanged: ESRD HCC 8; RxHCC HCC 19. Coefficients for these models are pending verification for payment year 2027. HHS-HCC: HCC 8 under the HHS-HCC 2026 benefit year mapping (no RAF; HHS-HCC weights vary by metal level). CMS-HCC V24: not used for payment year 2027 Medicare Advantage payment (CMS CY 2027 Rate Announcement). The PACE mapping is still pending verification for FY2027.

Source: CMS FY2027 ICD-10-CM order file. Payment model: CMS CY 2027 Rate Announcement. Read the FY2027 Official Guidelines.

Review the FY2026 April edition