C85.98
BillableNon-Hodgkin lymphoma, unspecified, lymph nodes of multiple sites
HCC Category Mapping
V28HCC 21 — Breast, Prostate, Colorectal and Other Cancers and Tumors
0.545V24HCC 10 — Lymphoma and Other Cancers
0.675ESRDHCC 10 — Lymphoma and Other Cancers
0.000RxHCCHCC 21 — Hodgkin Lymphoma and Other Cancers
0.000What This Code Means
Non-Hodgkin lymphoma of unspecified type affecting lymph nodes in multiple different locations throughout the body.
Coding Tips
- •Use this code when lymphoma involves two or more separate lymph node regions
- •Document all involved sites to support the 'multiple sites' designation
Clinical Significance
Non-Hodgkin lymphoma of unspecified type involving lymph nodes of multiple sites indicates disseminated nodal disease across two or more distinct anatomical regions. Multi-site involvement typically corresponds to advanced stage (III or IV) disease with implications for treatment intensity and prognosis. This widespread pattern often requires systemic therapy rather than localized treatment approaches.
Documentation Requirements
- ✓Documentation must specify at least two distinct lymph node regions involved, such as cervical and axillary or mediastinal and inguinal.
- ✓Staging workup results (PET-CT or CT), pathology with immunohistochemistry attempting subtype identification, treatment plan, and current disease status must all be recorded.
Commonly Confused Codes
Code Hierarchy
└C85Other specified and unspecified types of non-Hodgkin lymphoma└C85.9Non-Hodgkin lymphoma, unspecified└C85.98Non-Hodgkin lymphoma, unspecified, lymph nodes of multiple sites
└C85.98Non-Hodgkin lymphoma, unspecified, lymph nodes of multiple sites