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C85.91 ICD-10-CM Code: Non-Hodgkin lymphoma, unspecified, lymph nodes of head, face, and neck

C85.91 maps to CMS-HCC V28 21. A source-labeled RAF reference is available. Confirm the documented diagnosis and applicable coding requirements. MEAT criteria · RAF Calculator · HCC coding software

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Code lookupC85.91

FY 2026 Apr update / Neoplasms (C00-D49) / Malignant neoplasms of lymphoid, hematopoietic and related tissue (C81-C96)

C85.91

Billable / SpecificICD-10-CMOfficial ICD-10-CMCodebook guidance

Non-Hodgkin lymphoma, unspecified, lymph nodes of head, face, and neck

Non-Hodgkin lymphoma of unspecified type affecting the lymph nodes in the head, face, and neck region.

Buddy the Bee presenting code insight

Buddy Insight

Non-Hodgkin lymphoma, unspecified, involving lymph nodes of the head, face, and neck provides anatomical specificity but lacks subtype classification.

CMS-HCC V28

HCC 21

Coefficient HCC 21: 0.671 (Community Non-Dual Aged (CNA))

CMS-HCC V24

Historical

Historical

Not used for CY2026 payment

ACA/HHS

HCC 010

Code-level coefficient reference

ESRD/PACE

HCC 10

Code-level coefficient reference

RXHCC

HCC 21

Code-level coefficient reference

Inclusion Terms

Official
  • Lymphoma NOSInherited from C85.9
  • Malignant lymphoma NOSInherited from C85.9
  • Non-Hodgkin lymphoma NOSInherited from C85.9

Excludes 2

Official
  • Kaposi's sarcoma of lymph nodes (C46.3)Inherited from C81-C96
  • secondary and unspecified neoplasm of lymph nodes (C77.-)Inherited from C81-C96
  • secondary neoplasm of bone marrow (C79.52)Inherited from C81-C96
  • secondary neoplasm of spleen (C78.89)Inherited from C81-C96

Includes

Official

No Includes notes are included in this display for C85.91. Check the code and parent instructions in the Code Book.

Excludes 1

Official
  • other specified types of T/NK-cell lymphoma (C86.-)Inherited from C85
  • personal history of non-Hodgkin lymphoma (Z85.72)Inherited from C85

Code First

Official

No Code First sequencing instructions are included in this display for C85.91. Check the code and parent instructions in the Code Book.

Use Additional

Official

No Use Additional Code instructions are included in this display for C85.91. Check the code and parent instructions in the Code Book.

Code Also

Official

No Code Also instructions are included in this display for C85.91. Check the code and parent instructions in the Code Book.

Buddy Documentation Tip

HCC Buddy guidance
Confirmation that the lymphoma is non-Hodgkin type (not Hodgkin or other hematologic malignancy)
Clinical or imaging documentation confirming head, face, or neck lymph node involvement (cervical, submandibular, preauricular, occipital nodes)
Query for pathology results identifying the specific lymphoma subtype
If subtype cannot be determined, document the reason and note it is non-Hodgkin in nature

MEAT Support

HCC Buddy guidance
Confirmation that the lymphoma is non-Hodgkin type (not Hodgkin or other hematologic malignancy)
Clinical or imaging documentation confirming head, face, or neck lymph node involvement (cervical, submandibular, preauricular, occipital nodes)
Query for pathology results identifying the specific lymphoma subtype
If subtype cannot be determined, document the reason and note it is non-Hodgkin in nature

Audit Caution

HCC Buddy guidance
Not querying for lymphoma subtype when pathology results are available or pending
Confusing reactive cervical lymphadenopathy with lymphomatous involvement — biopsy confirmation is needed
Using this code for Waldeyer ring (tonsillar, adenoid) involvement which may be classified as extranodal rather than nodal
Accepting the unspecified subtype when provider documentation or pathology report contains classifiable information

Common Mistakes

HCC Buddy guidance
C81.x1 (Hodgkin lymphoma, lymph nodes of head, face, and neck) — Must distinguish Hodgkin from non-Hodgkin based on pathology
C85.11 (Unspecified B-cell lymphoma, head/face/neck) — If B-cell lineage is known, C85.11 is more specific
C83.31 (Diffuse large B-cell lymphoma, head/face/neck) — If DLBCL is confirmed, use the specific code
C85.90 (Non-Hodgkin lymphoma, unspecified, unspecified site) — Use C85.91 when head/face/neck nodes are documented

Current with CMS: FY2026 ICD-10-CM Apr 1 update (effective Apr 1 – Sep 30, 2026) · CMS-HCC V28, 100% phased in for payment year 2026. FY2027 code set already staged for October 1, 2026. How HCC Buddy stays current →

Is C85.91 an HCC code?

Yes. C85.91 (Non-Hodgkin lymphoma, unspecified, lymph nodes of head, face, and neck) maps to HCC 21, Lymphoma and Other Cancers under the CMS-HCC V28 risk adjustment model, with a source-labeled community non-dual aged reference coefficient of 0.671. Source-labeled code-level coefficients are references, not member totals. Actual contribution depends on complete member context, hierarchy and cleanup rules, interactions, and model year. HCC Buddy's RAF Calculator supports CMS-HCC V28 PY2026 and shows no score unless every required source and calculation check passes. It is billable for payment year 2026.

Coder answer: C85.91 is billable and maps to V28 HCC 21, Lymphoma and Other Cancers. Open it in the Code Book for the tabular path, RAF, and MEAT checklist.

Code
C85.91
Description
Non-Hodgkin lymphoma, unspecified, lymph nodes of head, face, and neck
HCC (V28)
HCC 21 — Lymphoma and Other Cancers
RAF reference coefficient
0.671
Billable
Yes
Payment year
2026

HCC Category Mapping

V28HCC 21, Lymphoma and Other Cancers
0.671
ESRDHCC 10, Lymphoma and Other Cancers
Not separately weighted
RxHCCHCC 21, Lymphomas and Other Hematologic Cancers
Not separately weighted

These are source-labeled model coefficients, not member totals. A category may still be removed by hierarchy or model cleanup rules. Weights are not directly comparable across models: CMS-HCC V28 and V24 use Community, Non-Dual, Aged; ESRD uses the dialysis continuing-enrollee model; RxHCC is the Part D continuing-enrollee, non-low-income, aged weight (a larger scale than CMS-HCC). ACA/HHS has no single weight — it varies by metal level. Actual per-patient RAF contribution depends on member context, hierarchy and cleanup rules, interactions, and the model year used by the payer. V28 is the CMS-HCC model phased in over payment years 2024–2026; V24 remains available for historical review.

Work C85.91 in the Code Book — tabular path, V28 RAF reference, and MEAT checklist →

MEAT review for C85.91

For C85.91, confirm that the documentation supports the diagnosis and meets the applicable coding, encounter, program and payer requirements. MEAT (Monitor, Evaluate, Assess, or Treat) is a review mnemonic, not a universal CMS coding rule.

  • MMonitor: signs, symptoms, disease progression, or lab trending documented in the note
  • EEvaluate: test results, medication response, or physical findings reviewed by the provider
  • AAssess: explicit mention in the assessment or plan with acknowledgment of status
  • TTreat: medication, referral, procedure, therapy, or counseling tied to the diagnosis

Coder workflow notes

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What This Code Means

C85.91 is the ICD-10-CM diagnosis code for non-hodgkin lymphoma, unspecified, lymph nodes of head, face, and neck. Non-Hodgkin lymphoma of unspecified type affecting the lymph nodes in the head, face, and neck region. C85.91 sits in the ICD-10-CM chapter for neoplasms (c00-d49), within the section covering malignant neoplasms of lymphoid, hematopoietic and related tissue (c81-c96).

Under the CMS-HCC V28 risk adjustment model, C85.91 maps to Lymphoma and Other Cancers (HCC 21) with a source-labeled community, non-dual, aged reference coefficient of 0.671. For CY2026 non-PACE Medicare Advantage, CMS uses 100% of the 2024 CMS-HCC model (V28). PACE uses a separate model blend. Source-labeled code-level coefficients are references, not member totals. Actual contribution depends on complete member context, hierarchy and cleanup rules, interactions, and model year. HCC Buddy's RAF Calculator supports CMS-HCC V28 PY2026 and shows no score unless every required source and calculation check passes.

Verify that the lymphoma is specifically in head, face, or neck lymph nodes rather than other sites. For C85.91, confirm that the documentation supports the diagnosis and meets the applicable coding, encounter, program and payer requirements. MEAT (Monitor, Evaluate, Assess, or Treat) is a review mnemonic, not a universal CMS coding rule. When documentation is ambiguous, coders should issue a provider query rather than assume the highest-specificity variant.

HCC Buddy maintains structured V28 and V24 mapping, source-labeled coefficient references, and MEAT documentation criteria for C85.91 sourced directly from the CMS-HCC risk adjustment model files and the CMS ICD-10-CM code set.

Coding Tips

  • Verify that the lymphoma is specifically in head, face, or neck lymph nodes rather than other sites
  • This code is appropriate when the specific NHL subtype is unknown but the location is documented

Clinical Significance

Non-Hodgkin lymphoma, unspecified, involving lymph nodes of the head, face, and neck provides anatomical specificity but lacks subtype classification. Head and neck nodal lymphoma is a common presentation for both indolent and aggressive NHL subtypes and requires pathology for proper classification. While more specific than C85.90, this code should still prompt a query for the lymphoma subtype.

Documentation Requirements

  • Confirmation that the lymphoma is non-Hodgkin type (not Hodgkin or other hematologic malignancy)
  • Clinical or imaging documentation confirming head, face, or neck lymph node involvement (cervical, submandibular, preauricular, occipital nodes)
  • Query for pathology results identifying the specific lymphoma subtype
  • If subtype cannot be determined, document the reason and note it is non-Hodgkin in nature

Commonly Confused Codes

  • C81.x1 (Hodgkin lymphoma, lymph nodes of head, face, and neck): Must distinguish Hodgkin from non-Hodgkin based on pathology
  • C85.11 (Unspecified B-cell lymphoma, head/face/neck): If B-cell lineage is known, C85.11 is more specific
  • C83.31 (Diffuse large B-cell lymphoma, head/face/neck): If DLBCL is confirmed, use the specific code
  • C85.90 (Non-Hodgkin lymphoma, unspecified, unspecified site): Use C85.91 when head/face/neck nodes are documented

Child Codes

Code Hierarchy

Also searched as

  • C85 91
  • C8591

For C85.91, confirm that the documentation supports the diagnosis and meets the applicable coding, encounter, program and payer requirements. MEAT (Monitor, Evaluate, Assess, or Treat) is a review mnemonic, not a universal CMS coding rule.

C85.91 maps to CMS-HCC V28 category 21, Lymphoma and Other Cancers. See the ICD-10 to HCC mapping hub for how the V28 crosswalk works. The mapping identifies a payment HCC category for C85.91. Review its source-labeled HCC coefficient above, check the RAF Calculator with complete member context for CMS-HCC V28 PY2026, and confirm the documentation the chart needs before the code is submitted. HCC Buddy shows no RAF score unless every required source and calculation check passes.

Work C85.91 in HCC Buddy

Open C85.91 in the Code Book for the full Index-to-Tabular path, MEAT checklist, and V28 HCC mapping, or in the Encoder to code from a keyword search. Pro includes 7 days to try everything, no card required.