C85.80
BillableOther specified types of non-Hodgkin lymphoma, unspecified site
Last updated: FY2026 ICD-10-CM (Oct 1, 2025 – Sep 30, 2026) | CMS-HCC V28 (100% phase-in, PY2026)
Is C85.80 an HCC code?
Yes. C85.80 maps to Breast, Prostate, Colorectal and Other Cancers and Tumors under the CMS-HCC V28 risk adjustment model (and Lymphoma and Other Cancers under V24).
HCC Category Mapping
RAF weights shown are the community, non-dual, aged base weights from the CMS risk adjustment model file. Actual per-patient RAF contribution depends on member segment, interactions, and the model year used by the payer. V28 is the CMS-HCC model phased in over payment years 2024–2026; V24 remains in use during the transition and for historical data.
MEAT Criteria for C85.80
For C85.80 to count as a valid HCC diagnosis in a given encounter, the provider's documentation must show MEAT: Monitor, Evaluate, Assess, or Treat. A diagnosis from a prior year does not carry forward automatically — it has to be re-documented and supported each calendar year.
- MMonitor: signs, symptoms, disease progression, or lab trending documented in the note
- EEvaluate: test results, medication response, or physical findings reviewed by the provider
- AAssess: explicit mention in the assessment or plan with acknowledgment of status
- TTreat: medication, referral, procedure, therapy, or counseling tied to the diagnosis
Only one of M/E/A/T is required to support the code, but the documentation must be specific enough to show that the provider actually addressed C85.80 during that encounter — not just copy-forwarded from a problem list.
What This Code Means
C85.80 is the ICD-10-CM diagnosis code for other specified types of non-hodgkin lymphoma, unspecified site. A rare or unusual type of non-Hodgkin lymphoma (a blood cancer) with no specific lymph node location identified. C85.80 sits in the ICD-10-CM chapter for neoplasms (c00-d49), within the section covering malignant neoplasms of lymphoid, hematopoietic and related tissue (c81-c96).
Under the CMS-HCC V28 risk adjustment model, C85.80 maps to Breast, Prostate, Colorectal and Other Cancers and Tumors (HCC 21) with a community, non-dual, aged base RAF weight of 0.545. Under the older CMS-HCC V24 model, C85.80 maps to Lymphoma and Other Cancers (HCC 10) with a community, non-dual, aged base RAF weight of 0.675. V28 is the CMS-HCC risk adjustment model that reached 100% phase-in for payment year 2026, replacing V24 which was used during the PY2024–PY2025 transition.
Use this code only when the specific site of lymph node involvement is unknown or not documented. Because C85.80 maps to a payment HCC, the provider's documentation must satisfy MEAT criteria (Monitor, Evaluate, Assess, or Treat) for the encounter to count toward the patient's Medicare Advantage risk adjustment score. When documentation is ambiguous, coders should issue a provider query rather than assume the highest-specificity variant.
HCC Buddy maintains structured V28 and V24 mapping, RAF weights, and MEAT documentation criteria for C85.80 sourced directly from the CMS-HCC risk adjustment model files and the CMS ICD-10-CM code set.
Coding Tips
- •Use this code only when the specific site of lymph node involvement is unknown or not documented
- •If site information becomes available, assign a more specific C85.8x code with the appropriate anatomical location
Clinical Significance
Other specified types of non-Hodgkin lymphoma at an unspecified site captures named NHL subtypes that do not have specific ICD-10 codes, such as intravascular large B-cell lymphoma, plasmablastic lymphoma, ALK-positive large B-cell lymphoma, or primary effusion lymphoma. These are typically rare, aggressive subtypes with unique clinical features and treatment approaches. The unspecified site should trigger a query for anatomical location.
Documentation Requirements
- ✓Pathology report identifying the specific non-Hodgkin lymphoma subtype by WHO classification name
- ✓Immunophenotyping and molecular studies confirming the specific entity
- ✓Query for anatomical site of involvement based on imaging or clinical findings
- ✓Documentation that the subtype does not have a more specific ICD-10 code (check C82, C83, C84, C86 categories first)