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C84.65 ICD-10-CM Code: Anaplastic large cell lymphoma, ALK-positive, lymph nodes of inguinal region and lower limb

C84.65 maps to CMS-HCC V28 20. A source-labeled RAF reference is available. Confirm the documented diagnosis and applicable coding requirements. MEAT criteria · RAF Calculator · HCC coding software

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Code lookupC84.65

FY 2026 Apr update / Neoplasms (C00-D49) / Malignant neoplasms of lymphoid, hematopoietic and related tissue (C81-C96)

C84.65

Billable / SpecificICD-10-CMOfficial ICD-10-CMCodebook guidance

Anaplastic large cell lymphoma, ALK-positive, lymph nodes of inguinal region and lower limb

This is a type of aggressive blood cancer (lymphoma) that starts in immune cells and is positive for a specific protein marker called ALK. The cancer is located in the lymph nodes in the groin area and lower leg.

Buddy the Bee presenting code insight

Buddy Insight

Anaplastic large cell lymphoma, ALK-positive, involving inguinal and lower limb lymph nodes indicates disease in the groin and lower extremity nodal basins.

CMS-HCC V28

HCC 20

Coefficient HCC 20: 1.136 (Community Non-Dual Aged (CNA))

CMS-HCC V24

Historical

Historical

Not used for CY2026 payment

ACA/HHS

HCC 010

Code-level coefficient reference

ESRD/PACE

HCC 10

Code-level coefficient reference

RXHCC

HCC 21

Code-level coefficient reference

Inclusion Terms

Official
  • Anaplastic large cell lymphoma, CD30-positiveInherited from C84.6

Excludes 2

Official
  • Kaposi's sarcoma of lymph nodes (C46.3)Inherited from C81-C96
  • secondary and unspecified neoplasm of lymph nodes (C77.-)Inherited from C81-C96
  • secondary neoplasm of bone marrow (C79.52)Inherited from C81-C96
  • secondary neoplasm of spleen (C78.89)Inherited from C81-C96

Includes

Official

No Includes notes are included in this display for C84.65. Check the code and parent instructions in the Code Book.

Excludes 1

Official
  • personal history of non-Hodgkin lymphoma (Z85.72)Inherited from C84

Code First

Official

No Code First sequencing instructions are included in this display for C84.65. Check the code and parent instructions in the Code Book.

Use Additional

Official

No Use Additional Code instructions are included in this display for C84.65. Check the code and parent instructions in the Code Book.

Code Also

Official

No Code Also instructions are included in this display for C84.65. Check the code and parent instructions in the Code Book.

Buddy Documentation Tip

HCC Buddy guidance
Pathology confirming ALCL with hallmark cells, ALK positivity, and CD30 expression
Physical exam or imaging documenting inguinal and/or lower limb lymph node enlargement
T-cell immunophenotype verified
Clinical staging

MEAT Support

HCC Buddy guidance
Pathology confirming ALCL with hallmark cells, ALK positivity, and CD30 expression
Physical exam or imaging documenting inguinal and/or lower limb lymph node enlargement
T-cell immunophenotype verified
Clinical staging

Audit Caution

HCC Buddy guidance
Confusing superficial inguinal nodes with deep intrapelvic iliac nodes — different anatomical locations and codes
Not confirming ALK status before code selection
Coding inguinal lymphadenopathy from infections or other malignancies as lymphoma without pathologic confirmation
Failing to update code when disease progresses beyond inguinal region

Common Mistakes

HCC Buddy guidance
C84.75 — ALCL, ALK-negative, inguinal/lower limb: Different ALK status with prognostic implications
C84.45 — PTCL-NOS, inguinal/lower limb: Different T-cell lymphoma subtype
C84.A5 — Cutaneous T-cell lymphoma, inguinal/lower limb: Skin-primary disease distinct from nodal ALCL
C84.66 — ALCL ALK-positive, intrapelvic: Deep pelvic nodes are distinct from superficial inguinal nodes

Current with CMS: FY2026 ICD-10-CM Apr 1 update (effective Apr 1 – Sep 30, 2026) · CMS-HCC V28, 100% phased in for payment year 2026. FY2027 code set already staged for October 1, 2026. How HCC Buddy stays current →

Is C84.65 an HCC code?

Yes. C84.65 (Anaplastic large cell lymphoma, ALK-positive, lymph nodes of inguinal region and lower limb) maps to HCC 20, Lung and Other Severe Cancers under the CMS-HCC V28 risk adjustment model, with a source-labeled community non-dual aged reference coefficient of 1.136. Source-labeled code-level coefficients are references, not member totals. Actual contribution depends on complete member context, hierarchy and cleanup rules, interactions, and model year. HCC Buddy's RAF Calculator supports CMS-HCC V28 PY2026 and shows no score unless every required source and calculation check passes. It is billable for payment year 2026.

Coder answer: C84.65 is billable and maps to V28 HCC 20, Lung and Other Severe Cancers. Open it in the Code Book for the tabular path, RAF, and MEAT checklist.

Code
C84.65
Description
Anaplastic large cell lymphoma, ALK-positive, lymph nodes of inguinal region and lower limb
HCC (V28)
HCC 20 — Lung and Other Severe Cancers
RAF reference coefficient
1.136
Billable
Yes
Payment year
2026

HCC Category Mapping

V28HCC 20, Lung and Other Severe Cancers
1.136
ESRDHCC 10, Lymphoma and Other Cancers
Not separately weighted
RxHCCHCC 21, Lymphomas and Other Hematologic Cancers
Not separately weighted

These are source-labeled model coefficients, not member totals. A category may still be removed by hierarchy or model cleanup rules. Weights are not directly comparable across models: CMS-HCC V28 and V24 use Community, Non-Dual, Aged; ESRD uses the dialysis continuing-enrollee model; RxHCC is the Part D continuing-enrollee, non-low-income, aged weight (a larger scale than CMS-HCC). ACA/HHS has no single weight — it varies by metal level. Actual per-patient RAF contribution depends on member context, hierarchy and cleanup rules, interactions, and the model year used by the payer. V28 is the CMS-HCC model phased in over payment years 2024–2026; V24 remains available for historical review.

Work C84.65 in the Code Book — tabular path, V28 RAF reference, and MEAT checklist →

MEAT review for C84.65

For C84.65, confirm that the documentation supports the diagnosis and meets the applicable coding, encounter, program and payer requirements. MEAT (Monitor, Evaluate, Assess, or Treat) is a review mnemonic, not a universal CMS coding rule.

  • MMonitor: signs, symptoms, disease progression, or lab trending documented in the note
  • EEvaluate: test results, medication response, or physical findings reviewed by the provider
  • AAssess: explicit mention in the assessment or plan with acknowledgment of status
  • TTreat: medication, referral, procedure, therapy, or counseling tied to the diagnosis

Coder workflow notes

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What This Code Means

C84.65 is the ICD-10-CM diagnosis code for anaplastic large cell lymphoma, alk-positive, lymph nodes of inguinal region and lower limb. This is a type of aggressive blood cancer (lymphoma) that starts in immune cells and is positive for a specific protein marker called ALK. The cancer is located in the lymph nodes in the groin area and lower leg. C84.65 sits in the ICD-10-CM chapter for neoplasms (c00-d49), within the section covering malignant neoplasms of lymphoid, hematopoietic and related tissue (c81-c96).

Under the CMS-HCC V28 risk adjustment model, C84.65 maps to Lung and Other Severe Cancers (HCC 20) with a source-labeled community, non-dual, aged reference coefficient of 1.136. For CY2026 non-PACE Medicare Advantage, CMS uses 100% of the 2024 CMS-HCC model (V28). PACE uses a separate model blend. Source-labeled code-level coefficients are references, not member totals. Actual contribution depends on complete member context, hierarchy and cleanup rules, interactions, and model year. HCC Buddy's RAF Calculator supports CMS-HCC V28 PY2026 and shows no score unless every required source and calculation check passes.

Verify the ALK-positive status is documented in the pathology report before assigning this code, as ALK-negative anaplastic large cell lymphoma uses a different code. For C84.65, confirm that the documentation supports the diagnosis and meets the applicable coding, encounter, program and payer requirements. MEAT (Monitor, Evaluate, Assess, or Treat) is a review mnemonic, not a universal CMS coding rule. When documentation is ambiguous, coders should issue a provider query rather than assume the highest-specificity variant.

HCC Buddy maintains structured V28 and V24 mapping, source-labeled coefficient references, and MEAT documentation criteria for C84.65 sourced directly from the CMS-HCC risk adjustment model files and the CMS ICD-10-CM code set.

Coding Tips

  • Verify the ALK-positive status is documented in the pathology report before assigning this code, as ALK-negative anaplastic large cell lymphoma uses a different code
  • Confirm the specific anatomical site (inguinal region and lower limb lymph nodes) is documented; if lymph nodes in other regions are also involved, additional codes may be needed to capture all affected sites

Clinical Significance

Anaplastic large cell lymphoma, ALK-positive, involving inguinal and lower limb lymph nodes indicates disease in the groin and lower extremity nodal basins. This presentation can cause lower extremity edema and discomfort. ALK-positive ALCL in this location must be distinguished from inguinal metastases of other malignancies and from other T-cell lymphoma subtypes presenting in this region.

Documentation Requirements

  • Pathology confirming ALCL with hallmark cells, ALK positivity, and CD30 expression
  • Physical exam or imaging documenting inguinal and/or lower limb lymph node enlargement
  • T-cell immunophenotype verified
  • Clinical staging
  • Documentation of active disease status

Commonly Confused Codes

  • C84.75: ALCL, ALK-negative, inguinal/lower limb: Different ALK status with prognostic implications
  • C84.45: PTCL-NOS, inguinal/lower limb: Different T-cell lymphoma subtype
  • C84.A5: Cutaneous T-cell lymphoma, inguinal/lower limb: Skin-primary disease distinct from nodal ALCL
  • C84.66: ALCL ALK-positive, intrapelvic: Deep pelvic nodes are distinct from superficial inguinal nodes

Child Codes

Code Hierarchy

Also searched as

  • C84 65
  • C8465

For C84.65, confirm that the documentation supports the diagnosis and meets the applicable coding, encounter, program and payer requirements. MEAT (Monitor, Evaluate, Assess, or Treat) is a review mnemonic, not a universal CMS coding rule.

C84.65 maps to CMS-HCC V28 category 20, Lung and Other Severe Cancers. See the ICD-10 to HCC mapping hub for how the V28 crosswalk works. The mapping identifies a payment HCC category for C84.65. Review its source-labeled HCC coefficient above, check the RAF Calculator with complete member context for CMS-HCC V28 PY2026, and confirm the documentation the chart needs before the code is submitted. HCC Buddy shows no RAF score unless every required source and calculation check passes.

Work C84.65 in HCC Buddy

Open C84.65 in the Code Book for the full Index-to-Tabular path, MEAT checklist, and V28 HCC mapping, or in the Encoder to code from a keyword search. Pro includes 7 days to try everything, no card required.