C84.17

Billable

Sézary disease, spleen

HCC Category Mapping

V28HCC 17 — Metastatic Cancer and Acute Leukemia

0.368

V24HCC 10 — Lymphoma and Other Cancers

0.675

ESRDHCC 10 — Lymphoma and Other Cancers

0.000

RxHCCHCC 19 — Lymphoma and Other Cancers

0.000

What This Code Means

A rare type of blood cancer (Sézary disease) that affects the spleen, characterized by abnormal T-cells that accumulate in the skin and lymphoid tissues.

Coding Tips

•Verify documentation confirms Sézary disease specifically involves the spleen as the primary site
•Do not use this code if the disease is in remission; use C84.1A instead

Clinical Significance

Sezary disease with splenic involvement indicates visceral organ spread in this aggressive leukemic cutaneous T-cell lymphoma. Splenic involvement may manifest as splenomegaly with cytopenias and indicates advanced systemic disease. This finding typically correlates with high tumor burden and poor prognosis, requiring intensive systemic therapy.

Documentation Requirements

✓Peripheral blood demonstrating circulating Sezary cells
✓Imaging documenting splenomegaly or splenic lesions
✓Skin biopsy confirming cutaneous T-cell lymphoma
✓Assessment for cytopenias related to splenic involvement
✓TNMB staging and treatment plan

Commonly Confused Codes

C84.07 — Mycosis fungoides, spleen: Distinct from Sezary disease; verify leukemic component C84.19 — Sezary disease, extranodal: Splenic involvement has its own specific code separate from general extranodal C84.10 — Sezary disease, unspecified site: Use C84.17 when splenic involvement is confirmed

Code Hierarchy

└C84Mature T/NK-cell lymphomas └C84.1Sézary disease └C84.17Sézary disease, spleen

└C84.17Sézary disease, spleen