C83.57
BillableLymphoblastic (diffuse) lymphoma, spleen
HCC Category Mapping
V28HCC 20 — Lung and Other Severe Cancers
0.000V24HCC 10 — Lymphoma and Other Cancers
0.675ESRDHCC 10 — Lymphoma and Other Cancers
0.000RxHCCHCC 21 — Hodgkin Lymphoma and Other Cancers
0.000What This Code Means
A type of blood cancer affecting immature lymphoid cells located in the spleen, an organ that filters blood and produces immune cells.
Coding Tips
- •Use this code when the spleen is the documented site of lymphoblastic lymphoma involvement
- •Splenic involvement may occur with or without lymph node involvement
Clinical Significance
Lymphoblastic lymphoma of the spleen is an uncommon extranodal site for this aggressive lymphoma. Splenic involvement may present with splenomegaly and cytopenias. Given the immature lymphoid cell origin, splenic involvement warrants bone marrow assessment to evaluate for leukemic transformation.
Documentation Requirements
- ✓Pathology confirmation from splenectomy specimen or splenic biopsy with TdT staining
- ✓Imaging documenting splenic involvement
- ✓CBC documenting cytopenias related to splenic disease
- ✓Bone marrow biopsy to exclude leukemic component
- ✓Splenectomy status if applicable
Commonly Confused Codes
C83.53 — Lymphoblastic lymphoma, intra-abdominal; spleen has its own specific codeC83.59 — Lymphoblastic lymphoma, extranodal; use C83.57 specifically for splenic involvementC83.37 — DLBCL, spleen; different lymphoma subtypeC83.07 — Small cell B-cell lymphoma, spleen; indolent vs. aggressive lymphoma
Code Hierarchy
└C83Non-follicular lymphoma└C83.5Lymphoblastic (diffuse) lymphoma└C83.57Lymphoblastic (diffuse) lymphoma, spleen
└C83.57Lymphoblastic (diffuse) lymphoma, spleen