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C83.18 ICD-10-CM Code: Mantle cell lymphoma, lymph nodes of multiple sites

C83.18 maps to CMS-HCC V28 20. A source-labeled RAF reference is available. Confirm the documented diagnosis and applicable coding requirements. MEAT criteria · RAF Calculator · HCC coding software

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Code lookupC83.18

FY 2026 Apr update / Neoplasms (C00-D49) / Malignant neoplasms of lymphoid, hematopoietic and related tissue (C81-C96)

C83.18

Billable / SpecificICD-10-CMOfficial ICD-10-CMCodebook guidance

Mantle cell lymphoma, lymph nodes of multiple sites

Mantle cell lymphoma is a type of cancer that affects white blood cells called lymphocytes and has spread to lymph nodes in multiple locations throughout the body. This is an aggressive form of non-Hodgkin lymphoma that typically affects older adults.

Buddy the Bee presenting code insight

Buddy Insight

Mantle cell lymphoma involving multiple lymph node sites indicates advanced-stage disease, which is the most common presentation for this lymphoma subtype.

CMS-HCC V28

HCC 20

Coefficient HCC 20: 1.136 (Community Non-Dual Aged (CNA))

CMS-HCC V24

Historical

Historical

Not used for CY2026 payment

ACA/HHS

HCC 010

Code-level coefficient reference

ESRD/PACE

HCC 10

Code-level coefficient reference

RXHCC

HCC 19

Code-level coefficient reference

Inclusion Terms

Official
  • Centrocytic lymphomaInherited from C83.1
  • Malignant lymphomatous polyposisInherited from C83.1

Excludes 2

Official
  • Kaposi's sarcoma of lymph nodes (C46.3)Inherited from C81-C96
  • secondary and unspecified neoplasm of lymph nodes (C77.-)Inherited from C81-C96
  • secondary neoplasm of bone marrow (C79.52)Inherited from C81-C96
  • secondary neoplasm of spleen (C78.89)Inherited from C81-C96

Includes

Official

No Includes notes are included in this display for C83.18. Check the code and parent instructions in the Code Book.

Excludes 1

Official
  • personal history of non-Hodgkin lymphoma (Z85.72)Inherited from C83

Code First

Official

No Code First sequencing instructions are included in this display for C83.18. Check the code and parent instructions in the Code Book.

Use Additional

Official

No Use Additional Code instructions are included in this display for C83.18. Check the code and parent instructions in the Code Book.

Code Also

Official

No Code Also instructions are included in this display for C83.18. Check the code and parent instructions in the Code Book.

Buddy Documentation Tip

HCC Buddy guidance
Pathology-confirmed mantle cell lymphoma
Documentation of at least two distinct lymph node regions involved
Comprehensive staging with PET/CT or CT documenting all involved sites
Ann Arbor stage (typically III or IV with multi-site involvement)

MEAT Support

HCC Buddy guidance
Pathology-confirmed mantle cell lymphoma
Documentation of at least two distinct lymph node regions involved
Comprehensive staging with PET/CT or CT documenting all involved sites
Ann Arbor stage (typically III or IV with multi-site involvement)

Audit Caution

HCC Buddy guidance
Using unspecified site code when documentation clearly shows multiple involved regions
Counting bilateral involvement of one region as multiple sites
Not coding multi-site involvement when staging shows disease in two or more distinct anatomical node groups

Common Mistakes

HCC Buddy guidance
C83.10 — Unspecified site; use C83.18 when multiple sites are documented, not when site is unknown
C83.19 — Extranodal/solid organ sites; C83.18 is for multiple nodal sites, not organ involvement
C83.38 — Diffuse large B-cell lymphoma, multiple sites; different histological subtype

Current with CMS: FY2026 ICD-10-CM Apr 1 update (effective Apr 1 – Sep 30, 2026) · CMS-HCC V28, 100% phased in for payment year 2026. FY2027 code set already staged for October 1, 2026. How HCC Buddy stays current →

Is C83.18 an HCC code?

Yes. C83.18 (Mantle cell lymphoma, lymph nodes of multiple sites) maps to HCC 20, Lung and Other Severe Cancers under the CMS-HCC V28 risk adjustment model, with a source-labeled community non-dual aged reference coefficient of 1.136. Source-labeled code-level coefficients are references, not member totals. Actual contribution depends on complete member context, hierarchy and cleanup rules, interactions, and model year. HCC Buddy's RAF Calculator supports CMS-HCC V28 PY2026 and shows no score unless every required source and calculation check passes. It is billable for payment year 2026.

Coder answer: C83.18 is billable and maps to V28 HCC 20, Lung and Other Severe Cancers. Open it in the Code Book for the tabular path, RAF, and MEAT checklist.

Code
C83.18
Description
Mantle cell lymphoma, lymph nodes of multiple sites
HCC (V28)
HCC 20 — Lung and Other Severe Cancers
RAF reference coefficient
1.136
Billable
Yes
Payment year
2026

HCC Category Mapping

V28HCC 20, Lung and Other Severe Cancers
1.136
ESRDHCC 10, Lymphoma and Other Cancers
Not separately weighted
RxHCCHCC 19, Leukemias and Other Hematologic Cancers
Not separately weighted

These are source-labeled model coefficients, not member totals. A category may still be removed by hierarchy or model cleanup rules. Weights are not directly comparable across models: CMS-HCC V28 and V24 use Community, Non-Dual, Aged; ESRD uses the dialysis continuing-enrollee model; RxHCC is the Part D continuing-enrollee, non-low-income, aged weight (a larger scale than CMS-HCC). ACA/HHS has no single weight — it varies by metal level. Actual per-patient RAF contribution depends on member context, hierarchy and cleanup rules, interactions, and the model year used by the payer. V28 is the CMS-HCC model phased in over payment years 2024–2026; V24 remains available for historical review.

Work C83.18 in the Code Book — tabular path, V28 RAF reference, and MEAT checklist →

MEAT review for C83.18

For C83.18, confirm that the documentation supports the diagnosis and meets the applicable coding, encounter, program and payer requirements. MEAT (Monitor, Evaluate, Assess, or Treat) is a review mnemonic, not a universal CMS coding rule.

  • MMonitor: signs, symptoms, disease progression, or lab trending documented in the note
  • EEvaluate: test results, medication response, or physical findings reviewed by the provider
  • AAssess: explicit mention in the assessment or plan with acknowledgment of status
  • TTreat: medication, referral, procedure, therapy, or counseling tied to the diagnosis

Coder workflow notes

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What This Code Means

C83.18 is the ICD-10-CM diagnosis code for mantle cell lymphoma, lymph nodes of multiple sites. Mantle cell lymphoma is a type of cancer that affects white blood cells called lymphocytes and has spread to lymph nodes in multiple locations throughout the body. This is an aggressive form of non-Hodgkin lymphoma that typically affects older adults. C83.18 sits in the ICD-10-CM chapter for neoplasms (c00-d49), within the section covering malignant neoplasms of lymphoid, hematopoietic and related tissue (c81-c96).

Under the CMS-HCC V28 risk adjustment model, C83.18 maps to Lung and Other Severe Cancers (HCC 20) with a source-labeled community, non-dual, aged reference coefficient of 1.136. For CY2026 non-PACE Medicare Advantage, CMS uses 100% of the 2024 CMS-HCC model (V28). PACE uses a separate model blend. Source-labeled code-level coefficients are references, not member totals. Actual contribution depends on complete member context, hierarchy and cleanup rules, interactions, and model year. HCC Buddy's RAF Calculator supports CMS-HCC V28 PY2026 and shows no score unless every required source and calculation check passes.

Verify documentation specifies 'multiple sites' of lymph node involvement before assigning this code; single site involvement requires a different code. For C83.18, confirm that the documentation supports the diagnosis and meets the applicable coding, encounter, program and payer requirements. MEAT (Monitor, Evaluate, Assess, or Treat) is a review mnemonic, not a universal CMS coding rule. When documentation is ambiguous, coders should issue a provider query rather than assume the highest-specificity variant.

HCC Buddy maintains structured V28 and V24 mapping, source-labeled coefficient references, and MEAT documentation criteria for C83.18 sourced directly from the CMS-HCC risk adjustment model files and the CMS ICD-10-CM code set.

Coding Tips

  • Verify documentation specifies 'multiple sites' of lymph node involvement before assigning this code; single site involvement requires a different code
  • Ensure the histology confirms mantle cell lymphoma and document the extent of lymph node involvement to support medical necessity for treatment planning

Clinical Significance

Mantle cell lymphoma involving multiple lymph node sites indicates advanced-stage disease, which is the most common presentation for this lymphoma subtype. Approximately 70-80% of mantle cell lymphoma patients present with Stage III or IV disease. Multi-site involvement necessitates systemic therapy and carries important prognostic implications.

Documentation Requirements

  • Pathology-confirmed mantle cell lymphoma
  • Documentation of at least two distinct lymph node regions involved
  • Comprehensive staging with PET/CT or CT documenting all involved sites
  • Ann Arbor stage (typically III or IV with multi-site involvement)
  • MIPI prognostic score documentation

Commonly Confused Codes

  • C83.10: Unspecified site; use C83.18 when multiple sites are documented, not when site is unknown
  • C83.19: Extranodal/solid organ sites; C83.18 is for multiple nodal sites, not organ involvement
  • C83.38: Diffuse large B-cell lymphoma, multiple sites; different histological subtype

Child Codes

Code Hierarchy

Also searched as

  • C83 18
  • C8318

For C83.18, confirm that the documentation supports the diagnosis and meets the applicable coding, encounter, program and payer requirements. MEAT (Monitor, Evaluate, Assess, or Treat) is a review mnemonic, not a universal CMS coding rule.

C83.18 maps to CMS-HCC V28 category 20, Lung and Other Severe Cancers. See the ICD-10 to HCC mapping hub for how the V28 crosswalk works. The mapping identifies a payment HCC category for C83.18. Review its source-labeled HCC coefficient above, check the RAF Calculator with complete member context for CMS-HCC V28 PY2026, and confirm the documentation the chart needs before the code is submitted. HCC Buddy shows no RAF score unless every required source and calculation check passes.

Work C83.18 in HCC Buddy

Open C83.18 in the Code Book for the full Index-to-Tabular path, MEAT checklist, and V28 HCC mapping, or in the Encoder to code from a keyword search. Pro includes 7 days to try everything, no card required.