C82.52
BillableDiffuse follicle center lymphoma, intrathoracic lymph nodes
HCC Category Mapping
V28HCC 21 — Breast, Prostate, Colorectal and Other Cancers and Tumors
0.545V24HCC 10 — Lymphoma and Other Cancers
0.675ESRDHCC 10 — Lymphoma and Other Cancers
0.000RxHCCHCC 21 — Hodgkin Lymphoma and Other Cancers
0.000What This Code Means
A type of cancer of the lymph system (diffuse follicle center lymphoma) located in the lymph nodes within the chest cavity.
Coding Tips
- •Intrathoracic involvement should be confirmed by chest imaging; document whether mediastinal or hilar nodes are affected
- •Chest involvement may cause respiratory symptoms; note any associated complications in documentation
Clinical Significance
Diffuse follicle center lymphoma involving intrathoracic lymph nodes may present with mediastinal or hilar lymphadenopathy that can cause compressive symptoms including superior vena cava syndrome, airway compromise, or pleural effusions. Intrathoracic disease often requires cross-sectional imaging for accurate staging and may influence the choice between systemic therapy and radiation. This presentation requires differentiation from other causes of mediastinal lymphadenopathy including sarcoidosis and other lymphoma subtypes.
Documentation Requirements
- ✓Pathology confirming diffuse follicle center lymphoma
- ✓Chest CT or PET/CT documenting intrathoracic lymph node involvement with measurements
- ✓Specification of which intrathoracic nodes are involved (mediastinal, hilar, paratracheal, etc.)
- ✓Assessment for compressive complications (airway, vascular, esophageal)
- ✓Staging documentation including assessment of other potential sites
Commonly Confused Codes
C82.62 — Cutaneous follicle center lymphoma, intrathoracic lymph nodes: Cutaneous variant originates in skin; verify the primary lymphoma typeC82.82 — Other types of follicular lymphoma, intrathoracic lymph nodes: Use C82.52 when diffuse follicle center type is confirmedC85.22 — Mediastinal (thymic) large B-cell lymphoma, intrathoracic: This is a distinct entity from diffuse follicle center lymphoma
Code Hierarchy
└C82Follicular lymphoma└C82.5Diffuse follicle center lymphoma└C82.52Diffuse follicle center lymphoma, intrathoracic lymph nodes
└C82.52Diffuse follicle center lymphoma, intrathoracic lymph nodes