C82.11
BillableFollicular lymphoma grade II, lymph nodes of head, face, and neck
HCC Category Mapping
V28HCC 21 — Breast, Prostate, Colorectal and Other Cancers and Tumors
0.545V24HCC 10 — Lymphoma and Other Cancers
0.675ESRDHCC 10 — Lymphoma and Other Cancers
0.000RxHCCHCC 21 — Hodgkin Lymphoma and Other Cancers
0.000What This Code Means
This is a type of cancer that starts in the lymph nodes located in the head, neck, and face area, where the cancer cells are growing at a moderate rate (grade II). Follicular lymphoma is a slow-growing blood cancer that affects the immune system's lymph nodes.
Coding Tips
- •The fifth character '1' indicates lymph nodes of head, face, and neck are involved; verify documentation specifies this anatomical location to ensure accurate coding
- •Grade II indicates intermediate differentiation; confirm the pathology report documents the specific grade, as different grades (I, II, III) have different code assignments and prognostic implications
Clinical Significance
Follicular lymphoma grade II involving head, face, and neck lymph nodes represents intermediate-grade disease in a readily palpable location. Grade II follicular lymphoma has a marginally more aggressive course than grade I and may transform to diffuse large B-cell lymphoma over time. Cervical lymphadenopathy is often the presenting finding that leads to biopsy and diagnosis.
Documentation Requirements
- ✓Pathology report specifying grade II follicular lymphoma (6-15 centroblasts per HPF)
- ✓Documentation of specific head, face, or neck lymph node involvement (cervical, submandibular, supraclavicular, etc.)
- ✓Ann Arbor staging
- ✓Assessment for transformation risk
- ✓Current treatment approach (observation, rituximab, chemoimmunotherapy)
Commonly Confused Codes
C82.01 — Grade I of same site; verify centroblast count — grade boundary matters for prognosisC82.21 — Grade III unspecified, head/face/neck; grade III has >15 centroblasts and is treated more aggressivelyC83.31 — Diffuse large B-cell lymphoma, head/face/neck; if transformation has occurred, use the diffuse large B-cell code insteadC82.1A — Grade II in remission; use only when remission is explicitly documented
Code Hierarchy
└C82Follicular lymphoma└C82.1Follicular lymphoma grade II└C82.11Follicular lymphoma grade II, lymph nodes of head, face, and neck
└C82.11Follicular lymphoma grade II, lymph nodes of head, face, and neck