C82.08
BillableFollicular lymphoma grade I, lymph nodes of multiple sites
HCC Category Mapping
V28HCC 21 — Breast, Prostate, Colorectal and Other Cancers and Tumors
0.545V24HCC 10 — Lymphoma and Other Cancers
0.675ESRDHCC 10 — Lymphoma and Other Cancers
0.000RxHCCHCC 21 — Hodgkin Lymphoma and Other Cancers
0.000What This Code Means
A slow-growing cancer of lymph cells (follicular lymphoma, grade I) affecting lymph nodes in multiple different areas of the body.
Coding Tips
- •Use this code when follicular lymphoma involves lymph nodes in three or more separate anatomical regions
- •Document all involved sites in the medical record for accurate staging and treatment planning
Clinical Significance
Follicular lymphoma grade I involving multiple lymph node sites indicates disseminated nodal disease across two or more non-contiguous anatomic regions. This is the most common presentation of follicular lymphoma, as most patients present with advanced-stage disease. Multi-site involvement typically corresponds to Ann Arbor stage III or IV disease.
Documentation Requirements
- ✓Pathology confirming follicular lymphoma grade I
- ✓Imaging (PET/CT preferred) documenting involvement of lymph nodes in two or more distinct anatomic regions
- ✓All involved sites listed in documentation
- ✓Ann Arbor staging with bulk assessment
- ✓FLIPI (Follicular Lymphoma International Prognostic Index) score if available
Commonly Confused Codes
C82.01-C82.07 — Single-site codes; use C82.08 only when two or more non-contiguous regions are involvedC82.09 — Extranodal sites; use C82.08 for purely nodal multi-site disease, C82.09 for solid organ involvementC82.18 — Grade II, multiple sites; verify pathology gradeC82.00 — Unspecified site; do not use unspecified when multiple specific sites are documented
Code Hierarchy
└C82Follicular lymphoma└C82.0Follicular lymphoma grade I└C82.08Follicular lymphoma grade I, lymph nodes of multiple sites
└C82.08Follicular lymphoma grade I, lymph nodes of multiple sites