C82.07
BillableFollicular lymphoma grade I, spleen
HCC Category Mapping
V28HCC 21 — Breast, Prostate, Colorectal and Other Cancers and Tumors
0.545V24HCC 10 — Lymphoma and Other Cancers
0.675ESRDHCC 10 — Lymphoma and Other Cancers
0.000RxHCCHCC 21 — Hodgkin Lymphoma and Other Cancers
0.000What This Code Means
A slow-growing cancer of lymph cells (follicular lymphoma, grade I) affecting the spleen.
Coding Tips
- •When follicular lymphoma involves the spleen, document whether it's the only site or part of multifocal disease
- •The seventh character indicates spleen involvement, which may affect staging and treatment decisions
Clinical Significance
Follicular lymphoma grade I involving the spleen indicates splenic infiltration, which is classified as a lymphoid organ site. Splenic involvement is relatively common in follicular lymphoma and typically identified on imaging as splenomegaly or focal splenic lesions. Splenic disease may impact staging and raise consideration for splenectomy in select cases.
Documentation Requirements
- ✓Pathology confirming follicular lymphoma grade I
- ✓Imaging documenting splenic involvement (splenomegaly, focal lesions, diffuse infiltration)
- ✓Spleen size measurement for monitoring response
- ✓Assessment for hypersplenism (cytopenias from splenic sequestration)
- ✓Ann Arbor staging (splenic involvement = stage III)
Commonly Confused Codes
C82.03 — Intra-abdominal lymph nodes; splenic hilar nodes are abdominal nodal, but splenic parenchyma involvement is coded C82.07C82.09 — Extranodal sites; the spleen is considered a lymphoid organ with its own code, not grouped with other extranodal sitesC82.17 — Grade II, spleen; verify grade specificationC82.08 — Multiple sites; use when spleen plus other regions are involved
Code Hierarchy
└C82Follicular lymphoma└C82.0Follicular lymphoma grade I└C82.07Follicular lymphoma grade I, spleen
└C82.07Follicular lymphoma grade I, spleen