C81.77
BillableOther Hodgkin lymphoma, spleen
HCC Category Mapping
V28HCC 21 — Breast, Prostate, Colorectal and Other Cancers and Tumors
0.545V24HCC 10 — Lymphoma and Other Cancers
0.675ESRDHCC 10 — Lymphoma and Other Cancers
0.000RxHCCHCC 21 — Hodgkin Lymphoma and Other Cancers
0.000What This Code Means
A type of Hodgkin lymphoma (blood cancer) that has spread to or originated in the spleen.
Coding Tips
- •Verify documentation confirms spleen involvement specifically, not just general abdominal involvement
- •Ensure this code is used only for 'Other Hodgkin lymphoma' subtype, not classical or nodular sclerosis variants
Clinical Significance
Other Hodgkin lymphoma with splenic involvement indicates extranodal spread to a major lymphoid organ by an uncommon histologic variant. Splenic involvement typically upstages disease to at least stage III and may present with left upper quadrant fullness, early satiety, or splenomegaly on exam. Treatment considerations include the potential for splenectomy and the implications for post-splenectomy immunization protocols.
Documentation Requirements
- ✓Pathology confirming Hodgkin lymphoma classified as 'other' subtype
- ✓Imaging or surgical confirmation of splenic involvement beyond simple splenomegaly
- ✓Ann Arbor stage III or higher designation
- ✓Documentation of splenic parenchymal involvement versus splenic hilar node disease
- ✓Active treatment or surveillance documentation
Commonly Confused Codes
C81.73 — Other Hodgkin lymphoma, intra-abdominal: abdominal lymph node disease is coded separately from splenic involvementC81.79 — Other Hodgkin lymphoma, extranodal/solid organ: use C81.77 specifically for the spleen; C81.79 covers other extranodal organsC81.97 — Hodgkin lymphoma, unspecified, spleen: use C81.77 when pathology identifies the subtype as 'other'
Code Hierarchy
└C81Hodgkin lymphoma└C81.7Other Hodgkin lymphoma└C81.77Other Hodgkin lymphoma, spleen
└C81.77Other Hodgkin lymphoma, spleen