C81.19
BillableNodular sclerosis Hodgkin lymphoma, extranodal and solid organ sites
HCC Category Mapping
V28HCC 21 — Breast, Prostate, Colorectal and Other Cancers and Tumors
0.545V24HCC 10 — Lymphoma and Other Cancers
0.675ESRDHCC 10 — Lymphoma and Other Cancers
0.000RxHCCHCC 21 — Hodgkin Lymphoma and Other Cancers
0.000What This Code Means
A type of Hodgkin lymphoma with nodular sclerosis pattern affecting organs or tissues outside the lymph node system.
Coding Tips
- •Character '9' denotes extranodal and solid organ involvement; specify which organs are affected in documentation
- •Seventh character is required to complete the code
Clinical Significance
Nodular sclerosis Hodgkin lymphoma of extranodal and solid organ sites indicates disease extending into organs or tissues outside the lymph node system. Extranodal extension in Hodgkin lymphoma may involve the lungs, liver, bone, or bone marrow and typically indicates advanced Stage IV disease. This presentation requires aggressive systemic chemotherapy and may carry a less favorable prognosis compared to purely nodal disease.
Documentation Requirements
- ✓Pathology confirming nodular sclerosis subtype
- ✓Documentation of specific extranodal organ(s) involved (lung, liver, bone, bone marrow, other)
- ✓Biopsy or imaging confirming extranodal disease
- ✓Ann Arbor Stage IV designation with 'E' suffix for extranodal extension
- ✓Bone marrow biopsy results
- ✓Treatment plan for advanced-stage disease
Commonly Confused Codes
C81.17 — Nodular sclerosis, spleen: Splenic involvement has its own code; use C81.19 for other organsC81.18 — Nodular sclerosis, multiple lymph node sites: Multiple nodal sites is different from extranodal organ involvementC81.10 — Nodular sclerosis, unspecified site: Use C81.19 when extranodal disease is documentedC81.09 — NLPHL, extranodal: Different subtype
Code Hierarchy
└C81Hodgkin lymphoma└C81.1Nodular sclerosis Hodgkin lymphoma└C81.19Nodular sclerosis Hodgkin lymphoma, extranodal and solid organ sites
└C81.19Nodular sclerosis Hodgkin lymphoma, extranodal and solid organ sites